PPT-NMR SPECTROSCOPY

1 NMR Console with Computer 2 RF Signal Generator Decoupler 1 H Amplifier Frequency Generator Transmitter Amplifier Frequency Generator 3 Frequency Generators and Signal Amplifiers are required for each RF channel . Outline. Types of water. Differential Scanning Calorimetry . Nuclear Magnetic Resonance Spectroscopy . Analytical determination of types of water. Summary. Purpose. Types of water are removed in different ways. 1. Diffusion Ordered Spectroscopy. Provides a way to separate different compounds in a mixture based on the differing translational diffusion coefficients (differences in the size and shape of a molecule). Freude. , Steffen . Beckert. , Frank . Stallmach. , Jörg . Kärger. , Jürgen . Haase. Universität. Leipzig. Institute . für. . Experimentelle. . Physik. Linnéstraße. . 5, 04103 . Leipzig, Germany. 1. 1. 2. Deduce the Structure. C. 4. H. 8. O. 2. 4.27 . ppm. (q, 1H); 3.91 (s, 1H); 2.22 (s, 3H); 1.39 (d, 3H). 2. 3. Deduce the Structure. 3. C. 9. H. 12. O. 6.58 (s, 1H); 6.52 (s, 2H); 3.74 (s, 3H); 2.27 (s, 6H).. Lecture . 9. Jan/Feb, 2016. Big picture. 1D. Review of how we do it. Why 2D?. What information does . 2D give?. Human Urine. Bouatra. et al:. Estimate at least 3079 compounds. NMR Implementation. http://wwwnmr.pharmazie.uni-marburg.de/www/jeol_magnet/fig6.jpg. Nuclear Magnetic Resonance. Powerful analysis. Identity. Purity. No authentic needed. Analyze nuclei. 1. H, . 13. C, . 31. P, . etc. Get information of how they are attached. Nuclear Magnetic Resonance. Intro . to NMR Spectroscopy. Nuclear . Magnetic Resonance . (NMR) spectroscopy . provides . structural information about organic . compounds and biomolecules. NMR . involves an interaction between electromagnetic radiation . 11.00 Gareth Morris . . Welcome. , introduction and history. 11.30 Peter . Kiraly. . Interferogram. . and real-time acquisition methods. 12.00 Laura . Castañar. . . Zangger. -Sterk. and band-selective methods. Introduction . to Spectroscopy. Spectroscopy involves an interaction between matter and light . (EMR). Light can be thought of as waves of energy or packets (particles) of energy called photons. Properties of light waves include wavelength and frequency. Introduction to Spectroscopy. 2. Spectroscopy. is the study of the interaction of matter with the electromagnetic spectrum. Electromagnetic radiation displays the properties of both particles and waves. For . CHEM 481 Lab. Objectives. Student should gain better understanding of NMR spectroscopy.. . Student should gain experience in the acquisition, processing, and displaying NMR data.. . Student should gain experience in interpreting NMR data in order to establish structure for unknown organic molecules.. Nuclear Magnetic Resonance Spectroscopy. Over the past fifty years nuclear magnetic resonance spectroscopy, commonly referred to as nmr, has become the preeminent technique for determining the structure of organic compounds. . Mass Spectrometry . Carbon-13 NMR. Proton NMR. Chromatography . 1. Infrared Spectroscopy. Absorption of infrared radiation causes bonds to vibrate. Different bonds absorb different wavelengths. These can be identified using the table on the data sheet. . . Endless. . Possibilities. Sjoerd J. Rijpkema. 02-03-2018. The . possibilities. of NMR. 2. Donovan. , K. J.; Griffin, R. G.; et. al J. Am. Chem. . Soc. ., 2016, 138, 9663--9674. . Chemical and 3D Structural Information of Small and Large .