PPT-Identification and design of optimal diets for human health and longevity

Michaela Murphy 123 Dudley Lamming 123 While calorie restriction CR is the gold standard for interventions that prolongs mammalian lifespan and healthspan adhering to reduced calorie diets is difficult for humans Recent findings by our lab and others have shown that protein restriction PR promotes health and longevity in mice and that lower consumption of dietary protein is associated with longevity and health in humans Our lab has found that the branchedchain amino acids BCAAs are key mediators of metabolic health and longevity with restriction of all three or specific BCAAs promoting metabolic health fitness and lifespan in mice We and others have also determined that dietary BCAAs are negatively associated with metabolic health in humans. F.I.T Tech VI Webinar . Don’t Be Fooled By Fad Diets!. When it comes to nutrition and fitness advice, a barrage of information comes at you every day. Its easy to get fooled by the quick-fix promise of a fad diet. . Leonid A. Gavrilov. Natalia S. Gavrilova. . Center on Aging . NORC and The University of Chicago . Chicago, USA. Approach . To study “success stories” in long-term avoidance of fatal diseases (survival to 100 years) and factors correlated with this remarkable survival success. World’s Oldest Human. Jeanne Calment . of Arles, France. 1875-1997. 122 . yrs. Longevity. is Heritable. From Gross L., 2006. Helen Reichert and siblings, as children and centenarians. Mollye. Marcus, 111 years old, and family. Longevity Risk Transfer: Where Does the Market Turn When All the Cheap Capacity is Gone. Longevity 12. September 2016. Laura Hardy. A Balancing Act. Servicing demand at a price that works. Is reinsurer longevity capacity running out?. Leonid A. Gavrilov. Natalia S. Gavrilova. . Center on Aging . NORC and The University of Chicago . Chicago, USA. Approach . To study “success stories” in long-term avoidance of fatal diseases (survival to 100 years) and factors correlated with this remarkable survival success. What are “Stochastic, Robust, and Adaptive” Controllers?. Stochastic Optimal. Control. Deterministic . versus. Stochastic . Optimization. Linear-Quadratic Gaussian (LQG). Optimal Control Law. Linear-Quadratic-Gaussian Control of a Dynamic Process. Longevity 12. September 2016. Laura Hardy. A Balancing Act. Servicing demand at a price that works. Is reinsurer longevity capacity running out?. Global exposure currently supports local appetite . US mortality exposure $12trn Sum Assured**. Objectives. Discuss the Standard American Diet and associated health outcomes. Define a Plant-Based diet. Outline the scientific evidence for the health benefits of Plant Based nutrition. Discuss the mechanisms by which Plant Based Nutrition promotes health. Michael Birt, PhD, Senior Advisor. Diana Nyad. Swam from Cuba to USA. 180 kilometers, without a shark cage. She was 64 years old. Others at 64. …. .. “Because . the rate of ageing varies immensely among . Don’t Be Fooled By Fad Diets!. When it comes to nutrition and fitness advice, a barrage of information comes at you every day. Its easy to get fooled by the quick-fix promise of a fad diet. . What is a Fad Diet?. Kimberly Kontson. , Biomedical Engineer, CDRH, FDA . Yarmela. Pavlovic. , Partner, Hogan Lovells US LLP. Kimberly Snyder. , Senior Partner, Validant. Moderated by. . Karen . Corallo. , Of Counsel, Skadden, Arps, Slate, Meagher & . Demetrios Kouretas. Professor, Animal Physiology - Toxicology. Is There a Way to Bridge the Gap Between Lifespan and . Healthspan. ?. Lifespan. Healthspan. Is Your Lifespan (and/or . Healthspan. ) “Programmed” in Your Genes?. University of Wisconsin Integrative Healthwww.fammed.wisc.edu/integrative Choosing Diet If you have formed the habit of checking on every new diet that comes along, you will find that, mercifully, th Table of Contents04 Introduction08 The 2 Targets 20 The 5 Strategies2627 Glossary 28 The EAT About EAT Photo credit: Shutterstock (page 8, 20, 22, 24, 25), iStock (page 6), Mollie Katzen (page 1