PPT-Enzyme and gene therapy of enzyme defects

Author : eleanor | Published Date : 2022-02-10

Therapy of enzyme defects general considerations How many organs are affected by the enzyme defect One organ a few or all organs How severe is the defect Can the

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Enzyme and gene therapy of enzyme defects: Transcript

Therapy of enzyme defects general considerations How many organs are affected by the enzyme defect One organ a few or all organs How severe is the defect Can the defect be adequately controlled by conventional treatment. G6PD Deficiency. (Glucose 6 phosphate . dehydrogenase. Deficiency). Objectives. To review the role of G6PD enzyme, and the red cell metabolism.. To define G6PD deficiency as a hemolytic anemia.. List the lab. Findings in G6PD deficiency.. Watch the PowerPoint presentation and copy the notes.. When finished, assemble in a lab group of 2 students and begin planning your experiment.. A rough overview of your experiment is due at the end of class that includes:. from Digital Gene Expression Sequencing Data. . Marius Nicolae . and Ion M. ă. ndoiu. (University of Connecticut, USA). Outline. DGE/SAGE-. Seq. protocol. EM algorithm. Experimental results. Conclusions. Objective. Students will model the process of using restriction enzymes and plasmids to form recombinant DNA.. Background Information. major tools of recombinant DNA technology are bacterial enzymes called restriction enzymes.. Figure 17.UN01. DNA. RNA. Protein. Figure 17.3b-1. Nuclear. envelope. DNA. Pre-mRNA. (b) Eukaryotic cell. TRANSCRIPTION. Figure 17.3b-2. RNA PROCESSING. Nuclear. envelope. DNA. Pre-mRNA. (b) Eukaryotic cell. Carol Eunmi Lee University of Wisconsin Evolution 410 Protein Evolution Outline (1) Types of Mutations that could affect function Structural Changes Regulatory Changes (2) Case study of structural changes ( of . replication. Double. -. stranded . DNA molecule. Parental (template. ) . strand. Daughter . (new. ) . strand. Bubble. Replication . fork. Two daughter . DNA molecules. (. b. ) Origins . of . replication . Objectives. -Understand how Restriction Enzymes digest DNA.. -Know how to construct a . pAMP. . (plasmid) or gel.. -Given the size of fragments, gel, know how to construct a restriction map.. -Given a restriction map know how to construct a gel.. Dr. Michael L. West. Division of Nephrology. Department of Medicine. Dalhousie University. Halifax NS. Canada. mlwest@dal.ca. Fabry Disease. . OMIM #301500. Glycosphingolipid= Gb3. Most specific therapies in Fabry disease increase . 1 In this exercise we will look at the catalytic behavior of enzymes. You will use Excel to answer the questions in the exercise section. At the end of this session, you must hand in answers to all 26 April 2021 GuidelineIntravenous Enzyme Replacement Therapy (ERT) This document reflects what is currently regarded as safe practice. However, as in any clinical situation, there may be Approved by Key Area . 1c. Lac. operon. Learning . I. ntentions. Understand how the . lac. operon works as an . examp. le of gene induction. Control of pathways. Genes that are . not required . can be . induced. learning objectives. Understand what is meant by genetic engineering.. Understand the steps involved.. Understand what restriction enzymes do.. Understand why sticky ends are important.. success criteria. -. The SSERC Team. Effect of competitive and non. –. competitive inhibitors on . . ‑galactosidase. Paul Beaumont / Kate Andrews /. Margaret Louis. b. -galactosidase. b. -galactosidase. Competitive inhibition.

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