PPT-Migraine Regulation of pain – the ascending pathway

Detection of an initial noxious stimulus is transmitted to the dorsal horn of the spinal cord via afferent sensory neurons 12 The majority of afferent inputs to the dorsal horn synapse with interneurons in the spinal cord allowing modulation of the signal. Know the Difference to Loosen the Vise. Program Goals. What Is a Migraine?. How Does Migraine Affect Quality of Life?. Episodic vs Chronic Migraine. Profiles of Episodic vs Chronic Migraine. Abbreviations. Care. Duren Michael Ready, MD FAHS ADAAPM. Director, Headache Clinic. Baylor Scott & White central division. DMReady@tamhsc.edu. Disclosures. Family Physician. Certified in Headache Medicine. Advanced . David Watson, MD. Director, WVU Headache Center. EPIDEMIOLOGY . AND IMPACT. Resolving barriers to care requires several interventions. Migraine is . a common, often disabling disease of the nervous system. David Lee Gordon, M.D., FAAN, FANA, FAHA. Professor and Chair. Department of Neurology. The University of Oklahoma Health Sciences Center. DLG DISCLOSURES. FINANCIAL DISCLOSURE. I have . nothing to disclose. Jafari. Headache Department, Iranian Center of Neurological Research, . Tehran . University of Medical Sciences, Tehran, Iran.. . Migraine is . 3 times more . prevalent in women than in . men by the age . CLINICAL CONDITIONS . IN WHICH 5-HT . PLAYS A ROLE . (. carcinoid syndrome and pulmonary . hypertension. .). The . most common types of headaches . are: . migraine, tension-type, . and cluster . headaches.. A64 Aura: A Study in a Ter�ary Care Centre Leelaba� Toppo 1 , bitya Chandra 2 1 Associate Professor, Department of General Medicine, Mallareddy Medical College for Women, Hyderab 1 4 Vulnerability to migraineTriggering migraine Migraine aura The frequency with which migraine attacks occur may vary from once in a lifetime to almost daily, an indication that the degree of migrai 1. Migraine. Migraine epidemiology. An estimated 1.3 billion individuals across the globe were estimated to have migraine in 2017. 1. In the WHO Global Burden of Disease study, ‘headache disorders’ has consistently been the 2. Stress, anxiety, excitement, and tension may all lead to a migraine attack. 1. Moreover, some people report reduction or relief of stress as a trigger – so-called ‘weekend’, or ‘let-down’ headaches. Migraine. Migraine through history. Migraine comes from the Greek word ‘. hemicrania. ’, which referred to pain occurring on one side of the head (‘half skull’). 1. The earliest descriptions of migraine are said to be from 3,000 BC. AMPP=American Migraine Prevalence and Prevention; COPD=chronic obstructive pulmonary disease; MHD=monthly headache day. 1. Buse et al. Headache 2020;60(10):2340–2356. Prevalence of various comorbidities among people with migraine based on headache frequency . An electronic diary study followed 62 people with migraine over 3 months. 1. The most the frequent trigger factors on headache days were . stress. , . fatigue. , and . sleep deprivation. 1. Headaches with trigger factors were more severe than those without trigger factors. 1. Turner et al. Headache 2019;59(4):495–508; 2. . Wöber. et al. J Headache Pain 2006;7(4):188–195; 3. . Pavlovic et al. Headache 2014;54(10):1670–1679; 4. . Sarchielli. . J Headache Pain 2006;7:172–173; .