PPT-Inherited retinal dystrophies the road to therapies

John Grigg Professor and Head Discipline of Ophthalmology Save Sight Institute Faculty of Medicine and Health The University of Sydney Disclosure Consultant to Novartis Usher Syndrome pathways to therapy. Traits. and. Learned Behaviors. 4.10 Science concepts. . The student knows that organisms undergo similar life processes and have structures that help them survive within their environment. The student is expected to: .  . October 29, 2012. The J. Wayne Reitz Union at the University of Florida. 8:00 am – 6:00 pm.  . *Breakfast will be served 30 minutes prior to the beginning of the meeting. "Therapy for Inherited Retinal Disease; Quo Vadis".  . October 29, 2012. University o f Florida, . Gainesville, Florida. 8:00 am – 6:00 pm.  . *Breakfast will be served 30 minutes prior to the beginning of the meeting. "Entering the Era of Treating Retinal Degenerative Disease". THROMBOPHILIA. Defects in physiologic anticoagulant pathways. Increased production of procoagulant. Antithrombin deficiency. Protein C deficiency. Protein S deficiency. Factor V . Leiden. Prothrombin G20210A gene mutation. RETINAL ANATOMY. *Choroid. *Retina. *Optic nerve. Retinal Vasculature. Central retinal artery. Branch retinal arteries. Arterioles. Capillaries . Venules. Branch retinal veins. Central retinal vein. Reasons for physician wanting FA. Group of progressive , usually bilateral , mostly genetically determined , non inflammatory . opacifying. disorders. Classification . Epithelial. Bowman layer. Stromal. Endothelial . Epithelial dystrophies. HEREDITARY MACULAR DYSTROPHIES. HEREDITARY MACULAR DYSTROPHIES. The hereditary dystrophies of the posterior segment constitute a large and . potentially confusing . group of disorders. . CLASSIFICATIONS. . Agrawal. Additional . Professor. Department of Ophthalmology. A.I.I.M.S, . Rishikesh. Acknowledgement. Photographs in this presentation are courtesy. of . Dr.Freund. . K. Bailey (The Retinal Atlas,2. Dr. . Vincent Yau-Wing Lee. Asia-Pacific . Vitreo. -retina Society. Types of Retinal . detachment. 1. . Rhegmatogenous. . (RRD). . accumulation of . subretinal. fluid via a retinal break. Types of Retinal detachment. 10/15/2019 1 Easy to diagnose but hard to remember Dr. Mohamed Abdelmoniem Mohamed Sedik Ophthalmology resident, MIOR 1. Bilateral. 2. Symmetrical. 3. Inherited condition. 4. Little or no relationsh Van Tıp Derg 25(4) : 538 - 5 43 , 2018 DOI: 10.5505/vtd.2018.74436 * Assista nt Prof . Lokman Balyen, Department of Ophthalmology, Faculty of Medicine, Kafkas University, Kars, Turkey. E - mail: C orneal dystrophies are a group of inherited, bilateral, gradually progressing, non- inammatory conditions caused by accumulation of extraneous material in the cornea. Changes usually begin Central AreolarChoroidal Dystrophy*Initially parafoveal pigmentary RPE changes progressing to enlarged RPE atrophy and eventually confluent chorioretinalatrophyVA deteriorates at age 3050 years but ma Caron J, Rolain J, Mura F, Guillot B, Raoult D, Bessis D. Rickettsia sibirica subsp. mongolitimonae Infection and Retinal Vasculitis. Emerg Infect Dis. 2008;14(4):683-684. https://doi.org/10.3201/eid1404.070859.