Radioisotopes can occur naturally or be produced artificially mainly in research reactors and accelerators They are used invarious fields including nuclear medicine where radiopharmaceuticals play a m ID: 891445
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1 RADIOISOTOPES AND RADIOPHARMACEUTICALS R
RADIOISOTOPES AND RADIOPHARMACEUTICALS Radioisotopes can occur naturally or be produced artificially, mainly in research reactors and accelerators. They are used invarious fields, including nuclear medicine, where radiopharmaceuticals play a major role.Radiopharmaceuticals are substances that contain a radioisotope, and have properties that make them effective markers inmedical diagnostic or therapeutic procedures. The chemical presence of radiopharmaceuticals can relay detailed information to medical professionals that can help in diagnoses and treatments. Eighty percent of all diagnostic medical scans worldwide use 99mTc, and its availability, at present, is dependent on the production of Mo in research reactors.Globally, the number of medical procedures involving the use of radioisotopes is growing, with an increasing emphasis on radionuclide therapy using radiopharmaceuticals for the treatment of cancer. Radioisotopes are the unstable form of an element that emits radiation to become a more stable form — they have certain special attributes. These make radioisotopes useful in areas such as medicine, where they are used to develop radiopharmaceuticals, as well as many other industrial applications. THE PRODUCTION OF TECHNETIUM 99 RADIOPHARMACEUTICALS:ONE POSSIBLE ROUTE IRRADIATED U-235 TARGETS 99m TCISIDEALFORDIAGNOSTICSBECASEOFITSSHORTHALFLIFE ( 6 HORS) ANDIDEAL GAMMAEMISSION 6 HORSMAKESDISTRIBTIONDIFFICLTITSPARENTCLIDE, MOLYBDEN 99 , ISPRODCED; ITSHALFLIFE ( 66 HORS) MAKESITITABLEFORTRANSPORT 99 MO 99 TCGENERATORSAREPRODCEDANDDISTRIBTEDARONDTHEGLOBE NUCLEAR REACTOR: TARGET IRRADIATIONHOSPITAL RADIOPHARMACY 99MO PROCESSING FACILITY99 MOLKLIQID 99 MO 99 TCGENERATORSMIXINGWITHBIOLOGICALMOLECLES THATBINDATDIFFERENT LOCATIONSINTHEBODY, PPORTINGWIDERANGEOFMEDICALAPPLICATIONS 99MO/99TC GENERATOR MANUFACTURER