PPT-Hypersensitivity Reaction

Dr Zahraa A Mohammed Learning objectives After reading this lecture you should be able to Distinguish between the four types of hypersensitivities and understand the immunological mechanisms behind each of them. immunology. What is hypersensitivity?. the violent reaction of the immune system leading to severe symptoms and even death in . sensitised. animal when it is re-exposed to the same antigen for the second time. It is nothing but allergy.. . . محمد فهد المسعود 431102617. عاصم فهد . الدهيش. 430106507. عوض . عبدالله. . الحربي 431102322. Introduction. the immune response uses multiple strategies to reduce damage to self by turning off responses when pathogen is cleared and avoiding reactions to self antigens. However, these checks and balances can break down, leading to immune-mediated reactions that are more detrimental than protective. . Normally immune is protective leading to only subclinical or localized response. Sometimes the response becomes exaggerated causing extensive tissue damage. Defined as - Injurious consequences in the sensitised host following subsequent contact with specific antigens.. The presence of redness, swelling and pain. .. Histologically. : . Presence of edema fluid and the infiltration of tissues by white blood cells. .. Inflammation can be triggered by may causes, physical, chemical or even biological.. Dr. Anil Kumar. Asst. professor, VCC, BVC (BASU), PATNA. Introduction. When . an animal is exposed to an antigen, it produces . a state of . increased reactivity . of the animal's tissues to . that antigen, and . Refif. . alshawk. (PhD). Lec. 2&3. Hypersensitivity – responding inappropriately to an antigen. Inflammatory response can have deleterious effects. Tissue injury. Disease. death. May develop in course of . 31. IgE based immunopatological reaction (type I, atopy).. 32. Allergens. Allergic diseases - causes, symptoms and diagnostics.. 33. Anaphylaxis (causes, symptoms and treatment).. 34. Examples of diseases based on immunopathological reaction type I. Treatment.. BY. . A.Swedha. Assistant Professor. Department of Microbiology. Jamal Mohamed College(Autonomous). . Trichy. HYPERSENSITIVITY. INTRODUCTION. . • Hypersensitivity can be defined as a state of altered immune response against an antigen characterized by hyper reactivity leading to immunopathology . -Was first termed . anaphylaxis. -can be systematic, which often leads to shock and can be fatal, or localized, which is various atopic reactions . Types of Reactions. There are four types of reactions. Definition. Injurious consequences in the sensitised host, following subsequent contact with specific antigens.. Gell. and Coombs Classification.  . Type- I. Type- II. Type- III. Type- IV. Immune response altered. Diseases of the immune system include: . hypersensitivity. reactions. , . autoimmune. disorders. , and . immunodeficiency. . states. .. Hypersensitivity. . reactions. occur as one of . four. types. Ns. Zaqqi ubaidillah, M. . Kep. ., . Sp. , . Kep. , MB. Hipersensitivitas. . . D. efinisi. . Allergic dysfunction . adanya. . gangguan. . respon. yang . dilakukan. . oleh. . pertahanan. natural . of pathology. Tuberculin. test. Submitted to- . Dr. . Sundareshan. . . Dr. P Sheela . . . Dept. of Veterinary microbiology. Tuberculin is the . dermatological test based on delayed type of hypersensitivity used for screening animals for tuberculosis. Make condition classes (hypersensitivity/allergy/. pseudoallergy. condition) primitive and assign the appropriate disease, disposition and reaction (process) classes underneath.. Redefine allergic diseases as diseases due to allergic reaction. This represents a reversion to a previous model..