PPT-Hypersensitivity Reaction

Dr Zahraa A Mohammed Learning objectives After reading this lecture you should be able to Distinguish between the four types of hypersensitivities and understand the immunological mechanisms behind each of them. Introduction. A. There are three types of immunological disorders. 1. Hypersensitivity. 2. Autoimmune disease. 3. Immunodeficiency. B. Hypersensitivity reactions to usually harmless substances are often called allergies or allergic reactions. . (Allergy and Anaphylaxis. Type I Hypersensitivity. . (Allergy and Anaphylaxis. ). IgE. -mediated hypersensitivity. Time: 2-30 . mins. Mechanism: . results from . IgE. antibodies bound to mast cells, when these . www.dentalelle.com. Pharmacology . ADVERSE REACTIONS. CHAPTER THREE. OBJECTIVES. Define and explain . the adverse reactions to drugs.. Explain the different types of adverse reactions that can occur such as . . Localized and Systemic Anaphylaxis. Updated: November . 29, . 2016. Folder Title: . IgEAllerNoTP. Chapter 15, 7. th. Edition,. . Kuby. Immunology, pp 485 to 516. Immunology and Medicine. (See Presentation Called “. Excessive immune response in a . sensitized . individual leading to tissue damage.. Types of Hypersensitivity:. Types I,II,III------>Immediate, Abs.. Type IV ------>Delayed, T cells.. Cooms. Normally immune is protective leading to only subclinical or localized response. Sometimes the response becomes exaggerated causing extensive tissue damage. Defined as - Injurious consequences in the sensitised host following subsequent contact with specific antigens.. Sravani Penumarty, MD. Linh-An Tuong, MD. Reena Khianey, MD . John Oppenheimer, MD. Ann Allergy Asthma Immunol. . June 2020;124(6):546-547. Prearthroplasty. Algorithm for the Evaluation of Metal Allergy in Patients with a History of Metal Hypersensitivity to Previous Orthopedic Implants. The presence of redness, swelling and pain. .. Histologically. : . Presence of edema fluid and the infiltration of tissues by white blood cells. .. Inflammation can be triggered by may causes, physical, chemical or even biological.. Aung. . Oo. DEN . 1114 . D218. What is dentin hypersensitivity?. A transient, sharp pain arising from exposed dentin in response to a . stimulus. Pain . – short in duration, very mild to very intense.. Dr. Anil Kumar. Asst. professor, VCC, BVC (BASU), PATNA. Introduction. When . an animal is exposed to an antigen, it produces . a state of . increased reactivity . of the animal's tissues to . that antigen, and . Refif. . alshawk. (PhD). Lec. 2&3. Hypersensitivity – responding inappropriately to an antigen. Inflammatory response can have deleterious effects. Tissue injury. Disease. death. May develop in course of . 31. IgE based immunopatological reaction (type I, atopy).. 32. Allergens. Allergic diseases - causes, symptoms and diagnostics.. 33. Anaphylaxis (causes, symptoms and treatment).. 34. Examples of diseases based on immunopathological reaction type I. Treatment.. Contact dermatitis – current model. Contact dermatitis – proposed revision. Is contact dermatitis always due to a topical exposure (i.e. contact with skin) to substance?. SYSTEMIC CONTACT DERMATITIS. Definition. Injurious consequences in the sensitised host, following subsequent contact with specific antigens.. Gell. and Coombs Classification.  . Type- I. Type- II. Type- III. Type- IV. Immune response altered.