PDF-CCN2 YAPs at cancer Andrew Leask CIHR Group in Skeletal Development an

In NIH 3T3 fibroblasts The CCN2 promoter is activated by the oncogenic transcriptional coactivator YAP and regulated by the YAP target TEAD Leask et al 2003 In an intriguing recent report Zhao. moreinformationhttp://www.suda.su.se/yaps Copyrightheldauthor(s).receiveonlyreview. amongadultsBergn Support: bones help support and provide shape to the body. Protection: provides protection to internal organs. Mineral storage: calcium and phosphorus make bones strong and help with oxygen. Hemopoiesis. System. No . bones about it!. 5 . Functions of the Skeletal System…. Provides shape . and supports . for . body. Allows for movement. Protects internal organs. Stores materials (calcium and lipids). Andrew Jackson. America’s First Crazy President. Overview:. America’s 7. th. President, 1829-1837. Responsible for the Trail of Tears* and Indian Removal Act*. Born in 1767 and died in 1845. Served in both the Revolutionary War and War of 1812*. The skeletal system is made up of organs called bones.. An adult human has 206 bones, but babies are born with 270 bones. Why?. The male and female skeleton have 1 major difference -what is it?. The female pelvis is wider and deeper. Why?. Sabrina Barner, Abbe Carlin, Amber Weigle. Neuromuscular Junctions. Communication link between nervous system and skeletal muscle fiber. Specialized intercellular connection. Each skeletal muscle fiber is controlled by a nerve cell. Quietly find your seat and get ready for class. Hand in skeleton projects below on chair. Fun Questions. How many bones are in the human body?. Have you ever broken a bone?. What is the largest bone in your body?. ~What are the functions of the skeletal system?. ~What are some disorders of the skeletal system?. ~How are skeletal disorders treated?. ~How does the skeletal system relate to the body’s systems of support and movement?. The Skeletal System . Skeletal System – bones of the body, shields important organs, gives your body shape. Skull protects the brain / Ribs Protect your heart and lungs / Back bone protects your spinal cord. Provides shape and support.. Enables us to move.. Protects your internal organs.. Produces blood cells.. Stores minerals such as calcium and phosphorous.. Bone Formation and Growth. As a baby, most of your skeletal system is made up of cartilage.. Warm up. What is the purpose of the skeletal system?. Week 4, Day Four. Warm up Response . Purpose:. to provide structure and support to the human body. Bones are where new blood cells are generated (in the marrow), and require the mineral . What is the process of bone formation?. What are the structures of the long bones?. What are the structures of the skeletal system? . The skeletal system. Compromises the bony framework of the body.. 559V Cartilage-hair hypoplasia is a rare, autosomal recessive skeletal dysplasia,caused by mutations in the gene. The skeletal abnormalities include CCCCCAAAAASSSSSEEEEE R R R REEEEPPPPPOOOOORRRRRTTT Degeneration Figure Legend:Figure 1Skeletal muscleDegeneration in a male Harlan SpragueDawley rat from a subchronic study. A central myofiber is swollen and hypereosinophilic(arrows), and a fragmented