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New Treatments for CTEPH New Treatments for CTEPH

New Treatments for CTEPH - PowerPoint Presentation

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Uploaded On 2019-01-21

New Treatments for CTEPH - PPT Presentation

Background Pathophysiology Background CTEPH Treatment Background 3 Approaches to CTEPH Treatment CTEPH Diagnosis and Imaging Initial Management of CTEPH CTEPH Management CTEPH Is Not Just a Clot Problem ID: 747384

merit cteph endpoint background cteph merit background endpoint 6mwd primary abbreviations chest treatment study management riociguat

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Presentation Transcript

Slide1

New Treatments for CTEPHSlide2
Slide3

Background

PathophysiologySlide4

Background

CTEPH TreatmentSlide5

Background

3 Approaches to CTEPH TreatmentSlide6

CTEPH Diagnosis and ImagingSlide7

Initial Management of CTEPHSlide8

CTEPH ManagementSlide9

CTEPH Is Not Just a Clot Problem Slide10

Summarizing PEA and BPASlide11

Medical Therapy

Riociguat Mechanism of ActionSlide12

CHEST-1

Mean Change From Baseline in 6MWDSlide13

CHEST-2

Long-Term Extension Study of

Riociguat for CTEPHSlide14

MERIT-1

Study DesignSlide15

MERIT-1

Primary EndpointSlide16

MERIT-1

Primary Endpoint By SubgroupSlide17

MERIT-1

Secondary Endpoint 6MWDSlide18

MERIT-1

SafetySlide19

CTEPH Trials in ProgressSlide20

International CTEPH Association (ICA)Slide21

ConclusionSlide22

AbbreviationsSlide23

Abbreviations (cont)