PPT-A NOVEL VSV-BASED EBOLA/HIV-1 VACCINE PROVIDES PROTECTION AGAINST SHIV IN MACAQUES

R4P 2021 Eric Arts on behalf of the VSVHIV vaccine team To work with Dr Chris Parks and IAVI to develop new VSVbased HIV vaccines that would propagate independent of VSV G andor HIV1 Env To design new HIV1 gp140 chimeras containing transmembrane and cytoplasmic tails from different viruses for optimal expression and antigen presentation on VSV particles. 573845744257452574555745557444573885737657462574555745357449574605738857376574565744557445573885737657456574555745557456573885737657459574635744557441574605738857376 VHPHQ5735957347VSLW5735957347RWKHU5734757536XLGV57356 Objects contaminated with the By: Calen Dehen. “Ebola is a hemorrhagic fever of the . filovirus. family with a 50-90% fatality rate. There is no effective treatment for Ebola except for the euphemistically labeled “supportive therapy.” The virus is spread through contact with infected fluids, typically blood, and once it has infected a new patient, it rapidly attacks the internal organs and connective tissue, causes severe bleeding, vomiting, aches, mental impairments and dementia, and in severe cases, grand mal seizures. The typical cause of death is multi-organ system failure” (Jones, 2011). . Endocytosis: the Dynamic Nature of the Endomembrane System. Notes to Instructors are italicized on slides and in notes. Context. 1 class session in Introductory Biology for majors. Taught in a large lecture hall. Compiled By: Dr. Shiv Mohan Verma. Stock is a liquid containing the juices of meat, bones or vegetables that have been extracted by long, slow cooking. Stocks are the foundation for many soup recipes, and are a wonderful way to use leftover meats and vegetables.. Virus . Disease: treatment, gaps and options. Ellis Owusu-Dabo . (BSc, MB ChB. , MSc, PhD, MWACP, FGCP) . Director, . KCCR/KNUST, Kumasi. , . Ghana . www.kccr-ghana.org. . Established in . October 1997. Intrarectal. Challenge with SHIV109CP3. Martin Markowitz MD. Aaron Diamond AIDS Research Center. An affiliate of the Rockefeller University. New York, New York. USA. Conflict of Interest. Research grants. Where did they get it?. How do you get the virus? . The EBOLA Health Commissioner. The EBOLA Health Commissioner . Understand science of disease and its transmission. Interrupt the transmission of the virus. Nithya Srinivas. 1. , John Fallon. 1. , Craig Sykes. 1. , Nicole White. 1. , Amanda Schauer. 1. , Lou Adamson. 2. , Michelle Matthews. 1. , Paul Luciw. 2. , Phil Smith. 1. , Angela DM Kashuba. 1. 1. University of North Carolina at Chapel Hill, Chapel Hill, United States, . Larry Corey, MD. Principal Investigator, NIAID supported HIV Vaccine Trials Network (HVTN). Past President and Director, Fred Hutchinson Cancer Research Center . Professor. , Laboratory Medicine and . phase . 1 clinical trial in HIV-1 infected . patients. Escaich Sonia, . COO . BIOSANTECH . SA.. Tat is a virulence factor of HIV. Transactivator. of transcription (Tat) of HIV-1 is essential for the viral . Archana Vidya Boopathy,. 1. Anurag Nekkalapudi,. 1. Bhawna Sharma,. 1. Sophie Schulha,. 2. . Raphaela. Wimmer,. 2. Debi Jin,. 1. Janette Sung,. 1. Jeffrey Murry,. 1. Mark Nagel,. 1. Brian Carr,. Engel GA, Pizarro M, Shaw E, Cortes J, Fuentes A, Barry PA, et al. Unique Pattern of Enzootic Primate Viruses in Gibraltar Macaques. Emerg Infect Dis. 2008;14(7):1112-1115. https://doi.org/10.3201/eid1407.071643. Richard A. . Koup. , MD. Acting Director. Vaccine Research Center. National Institute of Allergy and Infectious Diseases. National Institutes of Health. Bethesda, Maryland. Financial Relationships With Ineligible Companies (Formerly Described as Commercial Interests by the ACCME) Within the Last 2 Years:. A case study of ‘best practices’ in community engagement. Ms . Maureen . Njue . Dr Patricia . Njuguna. KEMRI . Wellcome. Trust Research Programme, Kenya.. . Outline . KEMRI-Wellcome Trust, Kilifi .