Raghda Ali Mohamed Contents Introduction Classification Shape Life cycle Clinical aspect Transmission Prevention I ntroduction In 1907 the parasite found in experimental laboratory mouse ID: 911922
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Slide1
Cryptosporidium
Presented by:
Raghda Ali Mohamed
Slide2Contents
Introduction.
Classification.
Shape.
Life cycle.
Clinical aspect.
Transmission.
Prevention.
Slide3Slide4I
ntroduction
In 1907 the parasite found in experimental laboratory mouse.
In 1955 the parasite recognized as cause of morbidity and mortality in young turkeys.
In 1976 cryptosporidium has emerged as human pathogen.
More than 40 species were isolated.
Slide5Classification
Eukaryote, zoonosis
phylum
: Apicomlexa
Class
: Sporozoasida
Sub class:
Coccidiasina
Species:
C.parvum(in human), C.muris, C.meleagridis, C.baileyi(birds), C.serpentis, C.nasorum(fish), C.felis(cats), C.warairi.
Slide6Shape
The oocyte of C.parvum is spherical or sub spherical.
S
mooth walled.
M
easured 4.5-5.5 microns in diameter.
C
ontains 4 naked sporozoites.
Non motile.
Slide7Life cycle
C.parvum is an obligate intracellular parasite and is monoxenous, completing its life in a single host.
All stages occur either in epithelial cells lining to the intestine or less
frequently in
the respiratory tract, with in vacuoles in plasma membrane and cytoplasm or in lumen.
Upon ingestion exposure of oocytes to the acid in stomach and alkali in intestine causes the 4 sporozoites to initiate the endogenous stages of sexual development in the epithelium.
.
Slide8Cont..
Several cycles of asexual reproduction (
merogony , schizony
)
After fusion of the gametes to form zygote
transforms
in to a thick walled oocyte then undergoes
sporogony
and excreted in the feces as sporulated.
Slide9Slide10Slide11Slide12Slide13Clinical aspects
Diarrhea
Weight loss
Dehydration
Abdominal cramps
The incubation period, time from ingestion organisms to the manifestation of symptoms ranges from 5-10 days but can be as much as 28 days.
In AIDS patients infection lead to death.
Slide14Transmission
-From person to person
-From ingesting oocyte contaminated food
-From inhaling oocytes
-From animals to human being
-From oocyst contaminated water
Slide15Slide16Conclusion
Cryptosporidium
is a microscopic parasite that causes the diarrheal disease cryptosporidiosis. Both the parasite and the disease are commonly known as "Crypto."
There are many species of
Cryptosporidium
that infect animals, some of which also infect humans. The parasite is protected by an outer shell that allows it to survive outside the body for long periods of time and makes it very tolerant to chlorine disinfection.
While this parasite can be spread in several different ways, water (drinking water and recreational water) is the most common way to spread the parasite.
Cryptosporidium
is a leading cause of waterborne disease among humans.
Slide17References
www.cdc.gov.parasite.crypto
www.healthlinkbc.ca.crypto
https://Books.google.com
Slide18T
hanks