PPT-OKN-007 as an Agent to Assist the Delivery of Anti-Cancer Drugs through the Blood-Brain

Barrier Rheal A Towner PhD Advanced Magnetic Resonance Center Oklahoma Medical Research Foundation What is OKN007 Small molecule Crosses bloodbrainbarrier Found to significantly decrease tumor volumes and significantly increase survival in several rodent glioma models mouse GL261 rat C6 F98 human xenograft U87 human pediatric 3752GBM PDX. Che. -An Lee. Phil . Medalie. Dan Schuster. Tom Elliot. Team Roles. Member. Role. Che. -An Lee. Industrial. Engineer/. Project Manager. Phil . Medalie. Mechanical Engineer. Dan Schuster. Mechanical. 1. 2. INTRODUCTION. Definition. : Cancer is a disease characterized by uncontrolled multiplication and spread of abnormal forms of the . body's own cells. .. The terms . cancer. , . malignant neoplasm. D.1 Pharmaceutical Products. Background In the Body Defenses . Non-specific Defense. Mechanisms. Specific Defense Mechanisms. First. Line: barriers to prevent entry. Second Line: attack pathogens. Third Line: immune system. . Adake. . MD. Associate Professor . Department of Pharmacology. Yenepoya. Medical College. MANGALORE. . Introduction. Also . called . as anti . neoplastic. . drugs . or . cytotoxic. agents.. Chairman of Pharmaceutical Technology Department, Faculty of Pharmaceutical Sciences and Pharmaceutical Industries, Future University in Egypt. New Trends in Nanotechnology-Based Targeted Drug Delivery Systems . Sympatholytics. ). Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. These . B Sahib . . Principles of Cancer Chemotherapy. Cancer chemotherapy . strives . to cause a lethal . cytotoxic. event or apoptosis in the cancer cell that can arrest a tumor's progression. . The . attack is generally directed toward DNA or against metabolic sites essential to cell replication for example, the availability of . PhD in Industrial Pharmacy and pharmaceutical formulations. Barriers to ophthalmic drug delivery: The big challenge. Advanced drug delivery . The aim of any final dosage form is to deliver the drug molecule in a therapeutic concentration to the site of action for an optimal period of time. . 8376 Int J Clin Exp Med 2015;8(6):8369-8376 [25] Dickson PV, Hamner JB, Sims TL, Fraga CH, Ng CY, Rajasekeran S, Hagedorn NL, McCarville MB, Stewart CF and Davidoff AM. Bevacizumab- induced transien MMngt. , CDE, PharmD, BCMAS (c) . WEST - HSJCC. October 17. th. , 2017 . 1. Disclosures : Mental Health Related . Expert Reviews / Presentations. Centre for Effective Practice. CPhA. McKesson Canada. Alzheimer's Disease (AD). Alzheimer's disease (AD) is the most common form of dementia and has become one of the biggest global healthcare challenges.. The pathophysiology of this disease is not fully understood.. F Abbas. Pharmacology. Malaria is a mosquito-borne infectious disease that affects humans and other animals. In . 2019 there were 229 million cases of malaria worldwide resulting in an estimated 409,000 deaths. . Rationale-. . Telangana. Rationale-. Covid-19, has been a major public health concern worldwide. India announced lockdown on 23rd March 2020, which led to halt of all the outpatient services, sample transportation and Anti TB drug delivery.. Mrs. Bharati M. Sonawane. Department of Pharmacognosy. Loknete Dr. J. D. Pawar College of Pharmacy, Manur. Kalwan.. . INTRODUCTION:. In modern era we have the option to use them over the synthetic molecules because herbal drugs have lesser side...