PPT-Glomerular diseases- 2 1

Glomerular diseases 2 Diseases leading to Nephritic syndrome 2 3 The Nephritic Syndrome Pathogenesis proliferation of the cells within the glomeruli accompanied by a leukocytic infiltrate . Dr Rebecca Martin F2. Learning objectives. Appreciate the fact that glomerular diseases fall onto a wide spectrum. Be able to define the nephritic and nephrotic syndromes. Understand the pathology of 4 key glomerular diseases which serve as archetypal examples of nephritic and nephrotic syndrome. Nephrotic. and Nephritic Syndromes. John Higgins. Learning Objectives. M. orphology of renal injury. Mechanisms of glomerular injury and . clinicopathologic. correlations of prototype disease with a typical clinical presentation. Dr. . Rida. . Shabbir. DPT KMU. Functions of kidney:. Excretion of metabolic waste products and foreign chemicals.. Regulation of water and electrolyte balance.. Regulation of body fluid osmolality and electrolyte concentration.. Learning objectives. Appreciate the fact that glomerular diseases fall onto a wide spectrum. Be able to define the nephritic and nephrotic syndromes. Understand the pathology of 4 key glomerular diseases which serve as archetypal examples of nephritic and nephrotic syndrome. 2. CLINICAL MANIFESTATIONS OF RENAL DISEASES. . 1-Azotemia. . refers to an elevation of blood urea nitrogen(BUN) and creatinine levels. It is largely related to a decreased glomerular filtration rate (GFR).. Obeidat. , MD. Histopathologist. /. Neuropathologist. I. . Glomerular. diseases. 1.Clinical Manifestations of Renal Diseases. - . The clinical manifestations of renal disease can be grouped into well-defined syndromes. . Hayam. . Hebah. Associate professor . of Internal . M. edicine. AL . Maarefa. college. GN means “ inflammation of glomeruli”.. The term is used to describe all types of glomerular diseases even those . Hazem.K.Al-Khafaji. FICMS. Department of internal medicine. College of medicine. Al-Qadissyia University. Glomerular diseases. Lecture-5-. Acute Nephritic . Syndromes. Clinical types, associations & causes. ecreased complement factor HDecreased complement factor IDecreased complement factor Becreased surface expression of membrane cofactor protein (MCP) in peripheral blood leukocytes by FACSerum antiCFHI J Stewart Cameron. São Paulo. Nephrology Division - University of São Paulo. 22. nd. October 2013. Renal Unit, Guy’s Campus, . King’s College, London UK. What can we learn from the story of glomerulonephritis about how knowledge is acquired and applied in medicine?. Columbia University Medical Center. Clinical Chief, Nephrology Division. New York, New York. Jai Radhakrishnan, MD. Professor of Medicine. Division of Nephrology. Medical Director. Clinical Trials Administration Office. Dr. Marwan Majeed Ibrahim. Glomerular diseases. Glomerular diseases account for a significant proportion of acute and chronic kidney disease. Most patients with glomerular disease do not present acutely and are asymptomatic until abnormalities are detected on routine screening of blood or urine samples. There are many causes of glomerular damage, including immunological injury, inherited diseases such as Alport’s syndrome, metabolic diseases such as diabetes mellitus, and deposition of abnormal proteins such as amyloid in the glomeruli. . TEXT read by the doctor is . coloured. RED. Extra notes are . coloured. maroon. Some pictures have extra information in the “notes” section so do not forget to read them. The doctor said she will mainly ask about what she reads, the skipped slides should be . and Nephritic Syndromes. John Higgins. Learning Objectives. M. orphology of renal injury. Mechanisms of glomerular injury and . clinicopathologic. correlations of prototype disease with a typical clinical presentation.