PPT-Class GWAS Odds Ratio, Increased Risk

Pvalue OR IR Lactose Intolerance rs4988235 09 27 12 Eye Color rs 7495174 0093 0 inf Asparagus rs4481887 084 235 118 Bitter Taste rs 713598 000498 022 0519 Earwax rs. Carsten Oliver Schmidt, Thomas Kohlmann Institute for Community Medicine, Methods in Community Medicine, University of Greifswald, Greifswald Submitted: 12 December 2007; Revised: 16 January 2008; Acc . of. . association. . Absolute, Relative and Attributable Risks. Hypothesis. . testing. . in. medicine. Outcomes or differences that we are interested in:. Differences in means or proportions. The Best Evidence. So far, we’ve learned that a good experiment or clinical trial is:. Randomized. Double-blind. Controlled. This is often abbreviated ‘RCT’: Randomized Controlled Trial.. Randomization. What is significant for the athlete, the statistician and team doctor?. important. Will Hopkins . will@clear.net.nz sportsci.org/will. What is a Statistic?. Simple, effect, and inferential statistics.. Statistical Significance,. Effect Size, and. Sample Size. Brief review. Causation vs. Correlation. When two variables A and B are correlated, there are four possibilities:. A causes B. B causes A. A common cause C causes both A and B. Statistical Significance,. Effect Size, and. Sample Size. Brief review. Causation vs. Correlation. When two variables A and B are correlated, there are four possibilities:. A causes B. B causes A. A common cause C causes both A and B. The Panel. Moderator. Niall Farrell, Director, Phinsys (Bermuda) Limited. The Panel. Yulia Bruskova, Lead Actuarial Director, Deloitte Bermuda. Umer Islam, Executive Director, E&Y Bermuda. Katrina E. Smith, Actuarial Consultant, Marsh Captive Solutions. ”? . (. for epidemiologists). Picture a 2x2 tables from Intro . Epi. :. (This is a collapsed table; there are no strata). Diseased. Undiseased. Total. Exposed. 13. 37. 50. Unexposed. 17. 133. 150. Total. Discussion . Week . 1. (4/1/13 – 4/5/13). Aims. Review key Stata commands. Categorical data. OR. RR. RD. Data manipulation. Stata. t. ab, . tabi. – basic tabling. cs. , . csi. – analysis of prospective/cross-sectional studies, single binary covariate. Verdict x Defendant Physical Attractiveness. Mock jurors were significantly more likely to find the defendant guilty when he was unattractive (75.7%) than when he was attractive . (65.0%), . . 2. (1, . interactions? Additive versus multiplicative interactions with dichotomous outcome variables Melanie M. Wall Departments of Psychiatry and Biostatistics New York State Psychiatric Institute and M Prof Kausik Ray, . BSc (. hons. ), . MBChB. , MRCP, MD, MPhil (. Cantab. ), FACC, FESC, FAHA. Professor of Cardiovascular Disease Prevention. St Georges University of London. Honorary Consultant Cardiologist St Georges Hospital. /class/. gene210/. files/lectures/2015/3%20GWASancestry.pptx. Height. Do “height” exercise in . Genotation. /traits/height. Fill out form.. Submit SNPs. SNPedia. The . SNPedia. website. http://www.snpedia.com/index.php/SNPedia. Exposure. (Risk Factor). Outcome. Target . Population. Study . population. Collect data. Make comparisons. Is there an association?. Are the results valid?. Chance. Bias. Confounding. Inference. Sample.