PPT-Genetics Part.1 Dr. Mohammed Hussein

MBChB MSC PhD DCH UK MRCPCH Part 1 SingleGene Disorders Part 2 Population Genetics Part 3 Cytogenetics Genetics SingleGene Disorders Basic Definitions 46 Chromosomes 22 pairs . by Ala Hazrat Imam Ahmed Raza Khan (may Allah shower mercy upon him) T ranslation by Aqib alQadri Zahe Izzat o Aetala - E Mohammed Ke Hai Arsh E Haq Zere Paa - E Mohammed ملسو ہیلع 񢜆 – MSc – PhD – MRCPCH – DCH (UK). Cutaneous Nerves . and. . Superficial Veins . of the . Upper Limb. The cutaneous nerves of the upper limb are described according to the regions they supply . M.B.Ch.B, MSC, PhD, DCH (UK), MRCPCH. Introduction . Numerical Chromosomal Abnormalities. Structural Chromosomal Abnormalities. Advances in Molecular Cytogenetics. Introduction. Chromosome abnormalities are:. M.B.Ch.B, MSC, PhD, DCH (UK), . MRCPCH. Cartilage is a specialized connective tissues possesses a firm pliable matrix that . resists mechanical . stresses. . The cartilage is . neither vascularized. M.B.Ch.B, MSC, PhD, DCH (UK), MRCPCH. Regional Anatomy. LOWER LIMB. Gateways . to . the lower . limb. There . are four major routes by which structures pass . from the . abdomen and pelvis into and out of the lower . M.B.Ch.B, MSC, PhD, DCH (UK), MRCPCH. Important principles that can characterize single-gene . diseases. Variable expression. Incomplete penetrance. Pleiotropy. Locus heterogeneity. New mutations. Delayed age of onset. Renal failure. Renal failure is defined as a significant loss of renal function in both kid. . to . the point of about 10-20% of the GFR.. Renal failure may . occure. as an acute and rapidly progressing process or may present as chronic form in which there is a progressive loss of renal function over a many yrs.. , MSC, PhD, DCH (UK), MRCPCH. Genetics. Lec.2. Mitochondrial . Inheritance. Mitochondria. Are cytoplasmic organelles involved in cellular respiration. Have their own chromosomes. This DNA encodes . 13 proteins . M.B.Ch.B, MSC, PhD, DCH (UK), MRCPCH. Definition. Population genetics is the study of genetic variation in populations. . Allow . us to understand how and why the prevalence of various genetic diseases differs among populations. Upgraded Lecture Note Series Jimma Universit y MOLECULAR BIOLOGY AND APPLIED GENETICS Lecture Note Series Democratic Republic of Ethiopia Ministry of Education and Ministry of Health The problem fa MBChB – MSc – PhD – MRCPCH – DCH (UK). The skeleton. The skeleton can be divided into 2 subgroups:. Axial skeleton: consists of bones of the . Skull (cranium). Vertebral column. Ribs and Sternum (Thoracic Cage). . Introduction. Tumor. . can be benign, pre-malignant, or malignant, whereas . cancer. is by definition malignant.. Cancer. . is a group of diseases characterized by . unregulated cell growth . and the . M.B.Ch.B, MSC, PhD, DCH (UK), . MRCPCH. Part . 1. Bone. Special type of connective . tissue. Has . a hard, . Mineralized. , extracellular . matrix. It is . Vascular. tissue . Although it . is one of the hardest substances of the body. M.B.Ch.B, MSC, PhD, DCH (UK), MRCPCH. Introduction . Regional anatomy. Connections & Gateways of the thigh. Compartments of the thigh. The Front and Medial Aspects of the Thigh. Cutaneous nerves.