4to 18yold patient identified with signs or symptoms suggesting ADHD Symptoms can come from parents direct concerns or the mental health screen recommended by the TFOMHSee TFOMH Algorithms Manypare ID: 899431
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1 ImplementingtheKeyActionStatements:AnAlg
ImplementingtheKeyActionStatements:AnAlgorithmandExplanationforProcessofCarefortheEvaluation,Diagnosis,Treatment,andMonitoringofADHDinChildrenandAdolescentsPracticeguidelinesprovideabroadoutlineoftherequirementsforhigh-qualityevidence-basedcare.Insup-portofconsistentandcomprehensivecareforchildrenandadolescentswithsymptomsofattentionandhyperactiv-itydisorderswithinatypical,busype-diatricpractice,theAAPhasdevelopedthefollowingsuggestedprocess-of-carealgorithm(seeSupplementalFig 4-to 18-y-old patient identified with signs or symptoms suggesting ADHD. Symptoms can come from parents direct concerns or the mental health screen recommended by the TFOMHSee TFOMH Algorithms Manyparentsbringtheirchild/adoles-centtotheprimarycareclinicianwithspecicconcernsaboutthechilds/ad-olescentsabilitytosustainattention,curbactivitylevel,and/orinhibitim-pulsivity.Inthesecases,itisclearthattheclinicianshouldinitiateanevalua-tionforADHD.However,inmanyin-stances,thechiefconcernmightin-cludebehaviorsandcharacteristicsassociatedwithADHDwithoutmentionofthecoreADHDsymptoms.Forexam-ple,children/adolescentsmighthavedifcultyremainingorganized,plan-ningactivities,orinhibitingtheirinitial Assess impact on treatment planFurther evaluation/referral as needed Exit this guideline.Evaluate or refer, as appropriate.Idenfy the child as CYSHCN if appropriate. Inattention and/or hyperactivity/impulsivity problems not rising to DSM-IV diagnosisProvide educaon of family and child re: concerns (eg, triggers for inaenon or hyperacvity) and behavior management strategies or school-based strategies Enhanced Coexisting disorders preclude primary care management? Follow-up and establish co-management planSee TFOMH Algorithms 4-to 18-y-old patient identified with signs or symptoms suggesting ADHD. Symptoms can come from parents direct concerns or the mental health screen recommended by the TFOMHSee TFOMH Algorithms See action statement 1Yes 24675Overview of the A See action statement 3 Provide educaon to family and child re: concerns (eg, triggers for inaenon or hyperacvity) and behavior-management strategies or school-based strategies Provide educaon addressing concern (eg, expectaons for aenon as a funcon of age)Enhanced SurveillanceYes diagnosis of Legend = Start= Continued care= Decision= Action/process Opon: Medicaon(ADHD only and past medical or family history of cardiovascular disease considered) Iniate treatment Titrate to maximum benet, minimum adverse eects Monitor target outcomes Opon: Behavior management (developmental variaon, problem or ADHD) Idenfy service or approach Monitor target outcomes Opon: Collaborate with school to enhance supports and services (developmental variaon, problem, or ADHD) Idenfy changes Monitor target outcomesSee action statement 5See action statement 6BEGIN TREATMENT Coexisting conditions? symptoms improve? Reevaluate to confirm diagnosis and/or provide education to improve adherence.Reconsider treatment plan including changing of the medication or dose, adding a medication approved for adjuvant therapy, and/or changing behavioral therapy.Yes chronic care management at least 2x/year for ADHD issues 3 Perform Diagnostic Evaluation for ADHD and Evaluate or Screen for Other/Coexisting Conditions: Family(parents, guardian, other frequent caregivers): Chief concerns History of symptoms (eg, age of onset and course over me) Family history Past medical history Psychosocial history Review of systems Validated ADHD instrument Evaluaon of coexisng condions Report of funcon, both strengths and weaknesses School (and important community informants): Concerns Validated ADHD instrument Evaluaon of coexisng condions Report on how well paents funcon in academic, work, and social interacons Academic records (eg, report cards, standardized tesng, psychoeducaonal evaluaons) Administrave reports (eg, disciplinary acons) Child/adolescent (as appropriate for childs age and developmental status): Interview, including concerns regarding behavior,
2 family relaonships, peers, school For a
family relaonships, peers, school For adolescents: validated self-report instrument of ADHD and coexisng condions Report of childs self-idened impression of funcon, both strengths and weaknesses Clinicians observaons of childs behavior Physical and neurologic examinaonSee action statements 23 Yes Apparently typical or developmental Yes ESTABLISH MANAGEMENT TEAM Identify child as CYSHCN Establish team including coordination plan Collaborate with family, school, and child to goals.See action statement 4 SUPPLEMENTALAPPENDIXFIGURE2ADHDprocess-of-carealgorithm.TFOMHindicatesTaskForceonMentalHealth;CYSHCN,child/youthwithspecialhealthcareneeds.FROMTHEAMERICANACADEMYOFPEDIATRICS initiatingthediagnosticevaluationmightbeappropriate.PerformDiagnosticEvaluationforADHDandEvaluateorScreenforCoexistingDisordersIdeally,theprimarycareofcestaffcanasktheassistanceoftheparent(s)inobtaininginformationonthepur-poseofavisitatthetimeofscheduling.Ifpossible,anextendedvisitisoftendesirablefortheevaluationofADHD.Asageneralapproachtotheinitialevaluation,dataonthechilds/adoles-centssymptomsandfunctioning(eg,homeorschoolquestionnaires)shouldbegatheredfromparents,schoolpersonnel,andothersources,preferablybeforethevisit.Thisstrat-egyallowstheprimarycarepediatri-ciantofocusonpertinentissuesforthatchild/adolescentandfamilyatthetimeofthevisit.Parentalconsenttoauthorizethereleaseofschooldatatopediatricprovidersisimportanttoob-tain.Theprocessmightbefacilitatedifthefamilyisgiventheresponsibilitytoprovideotherinformantswiththequestionnairesordata-collectionformstobeusedandtorequestotherrecordsandreports.TomakeadiagnosisofADHD,theclini-cianneedstoestablishthatatleast6ormorecoresymptomsperdimen-sionpresentedinSupplementalTablearepresentineitherorbothofthedimensionsofinattentionand/orDiagnosticcriteriaforADHDinschool-agedchildrenandadolescentsincludedocumentationofthefollowingcrite-Atleast6ofthe9behaviorsde-scribedintheinattentivedomainandtoadegreeincon-sistentwiththechildsdevelopmen-talage,and/orAtleast6ofthe9behaviorsde-scribedinthehyperactive/impul-sivedomainoccurandtoade-greeinconsistentwiththechildsdevelopmentalage.Presenceofsomeimpairmentin2ormoremajorsettings(eg,homeandschool)foratleast6months.PresenceofsomesymptomsofADHDthatcausedimpairment(ac-cordingtothehistory)before7yearsofage.Symptomshavepersistedforatleast6months.Evidenceofsignicantclinicalim-pairmentinsocial,academic,oroc-cupationalfunctioningbecauseofthebehaviors.Symptomsarenotattributabletoanotherphysical,situational,ormentalhealthcondition.criteriadene3subtypesofADHD:ADHDprimarilyoftheinattentivetype(ADHD/I,havingtheinappropri-atelyoftenoccurrenceofatleast6of9inattentionbehaviorsandhyperactive-impulsivebehaviors);ADHDprimarilyofthehyperactive-impulsivetype(ADHD/HI,havingtheinappropriatelyoftenoccurrenceofatleast6of9hyperactive-impulsivebehaviorsand6inattentionbe-haviors);andADHDcombinedtype(ADHD/C,hav- Perform Diagnostic Evaluation for ADHD and Evaluate or Screen for Other/Coexisting Conditions: Family(parents, guardian, other frequent caregivers): Chief concerns History of symptoms (eg, age of onset and course over me) Family history Past medical history Psychosocial history Review of systems Validated ADHD instrument Evaluaon of coexisng condions Report of funcon, both strengths and weaknesses (and important community informants): Concerns Validated ADHD instrument Evaluaon of coexisng condions Report on how well paents funcon in academic, work, and social interacons Academic records (eg, report cards, standardized tesng, psychoeducaonal evaluaons) Administrave reports (eg, disciplinary acons) Child/adolescent (as appropriate for childs age and developmental status): Interview, including concerns regarding behavior, family relaonships, peers, school For adolescents: validated self-report instrument of ADHD and coexisng condions Report of childs self-idened impression of funcon, both strengths and weaknesses Clinicians observaons of childs behavior Physical and neurologic examinaonSee acti
3 on statements 23 SUPPLEMENTALTABLE2Core
on statements 23 SUPPLEMENTALTABLE2CoreSymptomsofADHD(AdaptedFromtheDSM-IV-TR) InattentionDimensionHyperactivity-ImpulsivityDimensionHyperactivityImpulsivityCarelessmistakesFidgetyBlurtsanswersbeforequestionsarecompletedDifcultysustainingattentionUnabletostayseatedDifcultyawaitingturnSeemsnottolistenMovesexcessively(restless)Interrupts/intrudesonothersFailstonishtasksDifcultyengaginginleisureactivitiesquietlyDifcultyorganizingOnthegoTalksexcessivelyAvoidstasksthatrequiresustainedattentionLosesthingsEasilydistractedSupplementalAppendixPEDIATRICSVolume,Number, ingtheinappropriatelyoftenoccur-renceofatleast6of9behaviorsinboththeinattentionandhyperactive-impulsivedimensions).Thereisalsoevidencethatthecriteriaareappropriateforpreschool-agedandadolescents.TheuseofspecicDSM-IV-TRcriteriadecreasesvariationamongcliniciansinhowthediagnosisismadeandwillfacilitatecommunicationamongprofessionalsandpatients.DSM-IV-TRcriteriarequireevidenceofimpairingsymptomsbefore7yearsofage.Insomecases,thesymptomsofADHDmightnotberecognizedbypar-entsorteachersuntilthechildisolderthan7years,whenschooltasksbe-comemorechallenging.Inchildrenforwhomtheproblemsareidentiedaf-ter7yearsofage,historycanoftenidentifyanearlierageofonsetofsomeofthesymptoms.Delayedrecognitionmightbeseenmoreoftenintheinat-tentivesubtypeofADHD.Ifsymptomsarisesuddenly,withoutprevioushistory,primarycareclini-ciansshouldconsiderothercondi-tionsincludingheadtrauma,physicalorsexualabuse,neurodegenerativedisorders,moodoranxietydisorders,substanceabuse,oramajorpsycho-logicalstressinthefamilyorschool.Therequirementsthatachildmusthavesignicantimpairmentinfunc-tionandsomeimpairmentinatleast2settingsarethemostchallengingas-pectsoftheDSM-IV-TRcriteriaforthecliniciantoobtainaccurateinforma-tion.Thepresenceoffunctionalim-pairmentsisoftenthemosttroublingissueforchildren,families,andteach-ersandisacentralrequirementinmakingthediagnosisofADHDseeBehaviorManagement).Aswasdeterminedinthepreviousguideline,parentandteacherratingscalesthatuseDSM-IV-TRcriteriaforADHDarehelpfulinobtainingtheinfor-mationrequiredtomakeadiagnosisonthebasisoftheDSM-IV-TRcriteria.Broad-bandratingscalesthatassessmentalhealthfunctioningingeneraldonotprovidereliableandvalidindi-cationsofADHDdiagnosesbutmighthelpinscreeningforco-occurringbe-havioralconditions.Nocurrentinstrumentsroutinelyusedinprimarycarepracticereliablyas-sessthenatureordegreeoffunctionalimpairmentinchildrenwithADHD,al-thoughparent-reportinstrumentsmighthelp.Somemeasuresthatareavailablearelimited,becausetheymostlyprovideonlyaglobalrating(eg,theStrengthsandDifcultiesQues-tionnaire[SDQ]ImpactScaleandtheChildrensGlobalAssessmentScaleScale9)orhavemorelimitedvalida-tion(eg,theperformancecomponentoftheVanderbiltScales).Reviewofdocuments,suchasreportcardsandresultsofstandardizedtesting,andev-idenceofdetention,suspensions,orexpulsionsfromschoolcanalsoserveasevidenceoffunctionalimpairment.Withinformationobtainedfromtheparentandschool,theclinicianwillneedtomakeaclinicaljudgmentabouttheeffectofthecoreandasso-ciatedsymptomsofADHDonacademicachievement,classroomperformance,familyandsocialrelationships,inde-pendentfunctioningandsafety/acci-dentalinjuries,self-perception,leisureactivities,andself-care(suchasbath-ing,toileting,dressing,andeating).Ad-ditionalguidanceregardingfunctionalassessmentisavailablethroughtheAAPADHDtoolkitandtheTaskForceonMentalHealth.Intheabsenceofotherconcernsandndingsonmedicalhistory,familyandsocialhistory,andphysicalexamina-tionofthechild,nofurtherdiagnostictestingwillhelptoreachthediagnosis.Comparedwithclinicalinterviews,standardizedpsychologicaltests,suchascomputerizedtestsofattention,havenotbeenfoundtoreliablydiffer-entiatebetweenyouthwithandwith-outADHD.Appropriatefurtheras-sessmentisindicatedifanunderlyingetiologyissuspected.Assessmentssuchasscreeningforhighleadlevels,lowironorferritinlevelsorabnormalthyroidhormonelevelsorimagingstudiesshouldbepursuedonlyifotherhistoricorphysicalinformationsug-geststheirpresence.Conditionssuchassleepdisorders,suchasapnea,ab-senceseizures,hyperthyr
4 oidism,ormoodoranxietydisordersmightpres
oidism,ormoodoranxietydisordersmightpres-entwithADHDsymptomsandmightberelievedwhentheprimaryconditionisCurrentcriteriadonotdescribegen-derordevelopmentaldifferences,al-thoughnumerousstudieshavefoundthatthefrequencyofsymptomaticbe-haviorsvariessignicantlyacrossgenderandagegroups(forareview,seeBarkley).Comparedwithothergirls,girlswithADHDexperiencemoredepression,anxiety,distress,poorteacherrelationships,stress,externallocusofcontrol,andimpairedaca-demics.ComparedwithboyswithADHD,girlswithADHDexperiencemoreimpairmentinself-reportedanx-iety,distress,depression,andexternallocusofcontrol.Furthermore,thebe-havioralcharacteristicsspeciedintheDSM-IV-TR,despiteeffortstostan-dardizethem,remainsubjective,toagreatextent,andmaybeinterpreteddifferentlybydifferentobservers.Cul-turalnormsandexpectationsofpar-entsorteachersmayinuencetheperspectivesofvariousinformants.TheratesofADHDanditstreatmenthavebeenfoundtobedifferentfordifferentracial/ethnicgroups.clinicianmustremainsensitivetocul-turaldifferencesintheappropriate-nessofbehaviorsandperceptionsofmentalhealthconditions.Otherfac-tors,suchaspovertyandaccesstocare,likelycontributetotheculturalFROMTHEAMERICANACADEMYOFPEDIATRICS differences.ThesecomplexitiesinthediagnosismeanthatclinicianswhouseDSM-IV-TRcriteriamustapplytheminthecontextofsoundclinicalTheDSM-IV-TRdoesincludeacategoryofADHDnototherwisespecied.ThiscategoryismeantforchildrenwhomeetmanybutnotthefullcriteriaforADHD,suchaschildrenwhomeetallthesymptomandimpairmentcriteriabutwhoseageofonsetislaterthan7yearsorchildrenwhohaveclinicallysignicantimpairmentbutdonotmeetallthesymptomrequirements.Clinicallysignicantimpairmentisre-quiredindiagnosingachildwithADHD.Childrenwithinattentiveorhyperac-tive/impulsivesymptomsbutlessthansignicantimpairmentarecharacter-izedashavingproblems.Acomprehensivediagnosticevalua-tiontypicallybeginswithidentifyingfamilyschiefconcerns.Theclini-cianalsoneedstohavethefamilymemberscompleteavalidatedADHD.Familymembersshouldbeaskedtoprovideahistoryofsignsandsymptoms.Thishistoryincludesdeterminingtheonset,frequency,anddurationofproblembehaviors,situa-tionsinwhichtheyincreaseorde-crease,previoustreatmentsandtheirresults,andthefamilysunderstand-ingoftheissues.Thefamilyhistoryshouldincludeanymedicalsyn-dromes,developmentaldelays,cogni-tivelimitations,learningdisorders,ormentalillnessinfamilymembers,in-cludingADHDandmood,anxiety,andbipolardisorders.Inaddition,parentaltobaccoandsubstanceuseisrelevanttoriskfactorsforADHD.Familymem-bersmightnothavebeenformallydi-agnosedwithADHD;askingaboutfam-ilymembersschoolexperienceandproblemssimilartothoseofthepa-tientmightsuggestundiagnosedcasesofADHD.Updatingthemedicalhistorycanfo-cusonfactorsassociatedwithADHD,suchaspretermdelivery,neonatalproblems,congenitalinfections,andheadtrauma.Thepsychosocialhis-shouldincludeenvironmentalfac-tors,suchasfamilystressandprob-lematicrelationshipsthatmightcontributetothechilds/adolescentsoverallfunctioning.Itisimportanttoobtainhistoryofcon-ditionsthatmightmimicADHDsymp-tomsormightco-occurwiththecondi-tion.Co-occurringconditionsarediscussedlaterintheprocessalgo-rithm.Severalavailablequestion-nairesalsoprovideascreenforcoex-istingconditionsandareportof.Itisimportanttoobtainahistorythatwouldsuggestleadexpo-sure,absenceseizures,orothermen-talillnessessuchasanxietyormooddisordersandTourettedisorder.Afullreviewofsystemsmightalsorevealothersymptoms,suchassleepdistur-bances,thatmayassistinformulatingadifferentialdiagnosisand/ormaybeconsideredinthedevelopmentofman-agementplans.Thepatientshouldalsobescreenedforhearingand/orvisualPrimarysleepdisorders,suchasob-structivesleepapneasyndromeandrestless-legsyndrome/periodiclimb-movementdisorder,mightpresentwithsymptomsofinattention,hyper-activity,andimpulsivityorarefre-quentlyassociatedwithADHD.childrenbeingevaluatedforADHDshouldbesystematicallyscreenedforsymptomsof(ie,frequentsnoring,ob-servedbreathingpauses;restlesssleep,urgetomovetheirlegsatnight;daytimesleepiness)andriskfactorsfor(ie,adenotonsillarhypertrophy,asthma/allergies,obesity;familyh
5 is-toryofrestless-legsyndrome/periodicli
is-toryofrestless-legsyndrome/periodiclimb-movementdisorder,ironde-ciency)primarysleepdisorders.Sleep-assessmentmeasuresthathavebeenshowntobeusefulinthepediat-ricprimarycarepracticesettingin-cludebriefscreeningtoolsparent-reportsurveys.polysomnographyshouldbestronglyconsideredforchildrenwithsymp-tomssuggestiveofand/orriskfactorsforobstructivesleepapneasyndromeandrestless-legsyndrome/periodiclimb-movementdisorder.Inaddition,evenintheabsenceofpri-marysleepdisorders,modestreduc-tionsinsleepduration,suchasthoseassociatedwithenvironmentallyre-latedinsufcientsleep,mightbeasso-ciatedwithdetectabledeteriorationinvigilanceandattentioninchildrenwithADHDandshouldbeevaluatedandad-Commonclinicalpresenta-tionsofinsomniainchildrenwithADHDincludebedtimeresistance,de-layedsleeponset,nightwakings,andearly-morningawakening.Bothabase-lineassessment(ie,beforeinitiatingtreatment)andongoingperiodicscreeningforsleepproblemsshouldbeincludedinthemanagementofallchildrenwithADHD.Sleepdiariesareusefuladjunctsinquantifyingsleep-onsetlatencyandnightwakingsandassessingvariabilityinsleeppat-Thedifferentialdiagnosisofin-somniainchildrenwithADHDincludes:ADHDmedication(stimulantandnonstimulant)effects:Directeffectsonsleeparchitec-ture(ie,prolongedsleep-onsetla-tencyanddecreasedsleepdura-tion,increasednightwakings);andIndirecteffectssuchasinade-quatecontrolofADHDsymptomsintheeveningandmedicationwithdrawalorreboundSleepproblemsassociatedwithco-existingpsychiatricconditions(ie,SupplementalAppendixPEDIATRICSVolume,Number, anxietyandmooddisorders,disrup-tivebehaviordisorders).Circadian-basedphasedelayinsleep-wakepatterns,whichhavebeenshowntooccurinsomechil-drenwithADHD,whichresultsinbothprolongedsleeponsetanddif-cultywakinginthemorning.Inadequatesleephygiene(ie,incon-sistentbedtimesandwaketimes,absenceofabedtimeroutine,elec-tronicsinthebedroom,caffeineIntrinsicdecitassociatedwithADHD.NumerousstudieshavefoundthatnonmedicatedchildrenwithADHDandnocomorbidmoodoranx-ietydisordershavesignicantlygreaterbedtimeresistance,moresleep-onsetdifculties,andmorefrequentnightawakeningswhencomparedwithtypicallydevelopingcontrolchildren.Inaddition,somechildrenwithADHDseemtohaveev-idenceofincreaseddaytimesleepi-nessevenintheabsenceofapri-marysleepdisorder.Asoundassessmentoffunctioninginmajorareascanthenbeusedtocon-structaneducationalandbehavioralproleincludingnotonlyconcernsbutalsostrengthsortalents.ThemostcommonareasoffunctioningaffectedbyADHDincludeacademicachieve-ment;peer,parent,sibling,andadultauthority-gurerelationships;partici-pationinrecreationsuchassports;andbehaviorandemotionalregula-tion,includingriskybehavior.Onesys-tematicapproachtotheassessmentoffunctioncanusetheframeworkoftheInternationalClassicationofFunc-tioning,Disability,andHealth.SuggestionsandrecommendationsforscalessuchasthemodiedPatientHealthQuestionnaire-9ModiedforAdolescents(PHQ-A)andScreenforChildAnxietyRelatedEmotionalDisor-ders(SCARED)havebeendevelopedbytheAAPTaskForceonMentalThesituationmightbemorecomplicatedwhenparentsdisagree,particularlyindivorcesituationswhenparentswithsharedcustodyperceivethechildsproblemsandstrengthsdif-ferently.Undersuchcircumstances,theclinicianmustusecommunicationskillstondaconsensusonthediag-nosisandplan.Elicitinginformationfromextendedfamilymembersmighthelpclarifysomeofthedifferences.SCHOOLAND/OROTHERCOMMUNITYINFORMANTSMultipleinformantsarerequiredforclinicianstodeterminethenatureandseverityofsymptoms,impactofthesymptomsonfunctionin2ormoresettings,andwhetherthechild/adolescentmeetsDSM-IV-TRcriteriaforthediagnosisofADHD.Inmostcases,theteacherprovidesthosereports.ThereportsofparentsandteachersareoftensufcientfortheADHDdiagnosis,butinformationfromthepatientisessentialforiden-tifyingtheinternalizingconditionsofmoodandanxietydisorders.RatingscalesrecommendedbytheTaskForceonMentalHealthmaybehelp-ful.Insomecircumstances,itmightbedesirabletosolicitinformationfromadditionalsources.Schoolre-ports,forexample,mightbemoredifculttoobtainorlesscompre-hensiveincasesthatinvolvepreschool-agedchildrenandadoles-cents.Othe
6 radultswhoareactiveinthelifeofanadolesce
radultswhoareactiveinthelifeofanadolescent,suchascoaches,pastors,orscoutleaders,canbeaskedtocompleteratingscalestodevelopafullproleoftheadolescent,althoughtheaccuracyoftheirreportinghasnotbeenstudiedTeachersmightindicatetheirmajorbyusingquestionnairesorverbalinputbytelephoneorthroughdirectconversation.Anap-propriateschoolrepresentativeshouldbeaskedtocompleteadatedADHDinstrumentorbehav-iorscalebasedonDSM-IV-TRcriteriaforADHDandprovideobservationsthatmightsuggestcoexistingoral-ternativeconditions,includingdis-ruptivebehaviordisorders,depres-sionandanxietydisorders,tics,orlearningdisabilities.Reportof,bothstrengthsandweak-nesses,mightbegleanedbyques-tionnairesoracademicrecordsthatcanincludereportcards;stan-dardizedtestinginreading,mathe-matics,andwrittenexpression;vali-datedfunctionalassessmenttoolsmentionedpreviously;andprevi-ouspsychoeducationalevaluations.Theserecordscanhelpestablishachilds/adolescentsproleofaca-demicandbehavioralperformanceinschool,thepresenceofalearningdisability,difcultyinfollowingschoolrules,thequalityofpeerin-teractions,andtheextentofschoolIftherecordsindicatethatthechildishavingdifcultylearningaca-demicskills,thephysicianshouldde-termineifthechildhasbeenas-sessedforapotentiallearningproblembytheschool,becausethereisahighcomorbiditybetweenlearningdisabilitiesandADHD.Theschoolassessmentmightusearesponse-to-interventionmodelaspartofthediagnosticprocessinwhichlearningproblemsareevalu-atedonthebasisofthechildsre-sponsetoevidence-basedacademicinterventions,oramultidisciplinaryteamevaluationmightbeconductedbytheschool.IfthechildhasanIndi-vidualizedEducationProgram,thisdocumentshouldbereviewedbytheIfthechildcontinuestostrugglede-spitetheschoolsinterventionsandtreatmentforADHD,furtherpsychoe-ducationalorneuropsychologicalas-FROMTHEAMERICANACADEMYOFPEDIATRICS sessmentisnecessary.Theclinicianmightwanttorecommendthattheevaluationsbeperformedbyaninde-pendentpsychologistorneuropsy-chologist.Despitetheimportanceofthepsychologicalassessments,in-surancecoverageisquitevariable,andfamiliesshouldbeencouragedtoinvestigatetheircoveragewhenpursuingindependentpsychologicalevaluations.Financingcommunity-basedevaluationshasbeenad-dressedinapreviousAAPstate-ChildrenwithintellectualorotherdevelopmentaldisabilitiesmightalsohaveADHD,buttheas-sessmentinthesecasesismorecomplicated,becauseonemusten-surethattheacademicexpectationsarematchedtothechildsacademicabilitiesandthelevelofADHDsymp-tomsexceedswhatwouldbeex-pectedforachildsdevelopmentallevel.Primarycarephysiciansin-volvedinassessingADHDinchildrenwithintellectualdisabilitieswillneedtocollaboratecloselywithaschoolpsychologistorindependentInadditiontotheacademicinforma-tion,informationshouldbere-questedthatcharacterizesthechilds/adolescentsleveloffunc-tioningwithregardstopeer,teacher,andotherauthoritygurerelationships;abilitytofollowdirec-tions;organizationalskills;historyofclassroomdisruption;andassign-mentcompletion.ofdisciplinaryaction,suchassuspensionsandexpulsions,anddescriptionsofbehavioratschoolreectsocialfunctionandbehav-ioralregulationandsuggestthepos-sibilityofcoexistingconditions.Foradolescentswhohavemultipleteachers,itisdesirabletoobtainbe-haviorandimpairmentratingsfromatleast2teachersinacademicsubjects(eg,mathandEnglishteachersor,forchildren/adolescentswithlearningdisabilities,ateacherintheareaofstrongfunctionandateacherintheareaofweakfunction).TheADHDtool-providesmaterialsrelevanttothisschooldatacollection.Teacherandparentreportsfrequentlyandtherealsomightbedis-agreementbetweenparents.Theseob-servationsmightnotbeinaccurate,becauseparentsandteachersob-servethechildrenunderdifferentcir-cumstances.Whenthereisdisagree-ment,itishelpfultoobtainmoreinformationsuchasthecircumstanceunderwhichtheindividualsobservedthechild,thedemandsonthechildduringthoseobservations,theobserv-ersunderstandingofthebehaviorsandhowtodealwiththem,andtheob-serversunderstandingofADHDandhowitistreatedaswellastheroletheyplaywiththechild.Asnotedpre-viously,obtaininginformationfromad-ditionalsources,suchasgrandpar-ents,coaches,or
7 Sundayschoolteachers,canbehelpful.Thecli
Sundayschoolteachers,canbehelpful.Theclini-ciansdecisionaboutthediagnosisisaclinicaljudgmentmadeonthebasisofalltheinformationthatisavailable.Theclinicianshouldconductanage-,includingthechilds/adolescentsconcernregardinghisorherownbehavior,andregardingfamilyrelationships,peers,andschool.Itisimportanttoincludeadiscussionofhisorherstrengths,goals,anddifcul-ties.Alongwiththeinterview,theuseofanappropriatevalidatedself-reportinstrumentofADHDandco-existing,primarilyforadolescents,canaidintheassessmentofriskofADHDandanxietyandmooddisorders.Itisalsoimportanttoaskaboutdelusionalthinkingandsuicidalthoughtsorac-tions.Thisevaluationshouldalsopro-videabaselineofthechilds/adoles-centsself-identiedreportoffunctionathome,inschool,atwork,andamongpeersaswellasvalidatedfunctionalas-sessmenttools.Wheneverpossible,theindividualchildsoryouthsownviewofwhatheorshewouldliketoseechangedshouldbeconsideredprimarytargetsforintervention,becausethesegoalsmightattimesdifferwidelyfromparentorschoolconcerns.Theclinicianmustkeepinmindthetendencyofmanychildren/adoles-centstounderreporttheirADHDandotherdisruptivebehaviorsymptoms.However,thebaselineimpressionsofthechild/adolescentcanthenbeusedasthebasisforshapingthepatientsunderstandingofADHDandcoexistingsymptomsaswellasmonitoringfunc-tioninsocial,behavioral,andaca-demicdomains.Activeinvolvementofthechildren/adolescentsmightbeusefultoempowerthemtounder-standandparticipateintheirowndi-agnosticformulationand,later,toob-tainbuyintotheirtreatmentplanandimproveadherencetotreatment.RecommendationsoftheAAPTaskForceonMentalHealthandtheGuide-linesforAdolescentDepressioninPri-maryCare(GLAD-PC)includeusingvalidateddiagnosticratingscalesforadolescentmoodandanxietydisor-dersforclinicianswhowishtousethisformat.Inaddition,theCRAFFT(car,re-lax,alone,forget,friends,trouble)isanavailablescreenforsubstanceofthepatientshouldberecordedandincludehisorherlevelofattention,activity,andim-pulsivityduringtheencounter.Anim-portantcaveatisthatthendingsseeninothersettings,includingcoresymp-toms,areoftennotobservedduringofcevisits.Specialattentionshouldbepaidtolan-guageskillsinpreschool-agedandyoungschool-agedchildren,becausedifcultieswithlanguagecanbeasymptomofalanguagedisorderandSupplementalAppendixPEDIATRICSVolume,Number, predictorofsubsequentreadingprob-lems;suchlanguagedisordersmightpresentasproblemswithattentionandimpulsivity.Likewise,socialinter-actionsshouldbenotedduringtheex-amination,becausetheyareanotherpossibleareaofdeciency.physicalandneurologicexami-mustbecomprehensive.Aphysicalandneurologicexaminationshouldbeconductedtodetermineiffurthermedicalordevelopmentalas-sessmentsareindicated.Baselineheight,weight,bloodpressure,andpulsemeasurementsshouldbetaken.Amongthesignstonotearehearingandvisualacuityandcardiovascularstatus.Dysmorphicfeaturesshouldalsobenoted,becauseADHDmightbeassociatedwithgeneticsyndromes(eg,fetalalcoholsyndromeandfragileX).Theneurologicevaluationshouldincludedevelopmentalandmentalsta-tusobservationsincludingaffect;com-municationskills,includingspeechandlanguage;tics;andgrossandnemotorcoordination.ManychildrenwithADHDwillhavepoorcoordination,whichmightbesevereenoughtowar-rantadiagnosisofdevelopmentalco-ordinationdisorder.Thendingscanaffecthowwellthechildcanperformincompetitivesportsandcanalsoad-verselyaffecthisorherwritingskills.Throughhistoryandexaminationofthechildsneandgrossmotorskills,thecliniciancanidentifythesedecitsandaddresstheminthemanagement diagnosis of Asaresultofthediagnosticevalua-tion,aprimarycareclinicianshouldbeabletoanswerthefollowingques-Howmanyinattentiveandhyperac-tive/impulsivebehaviorcriteriaforADHDdoesthechild/adolescentmeetacrossthemajorsettingsofhisorherlife?Havethesecriteriabeenpresentfor6monthsorlonger?Wastheonsetoftheseorsimilarbehaviorspresentbeforetheageof7years?Whatfunctionalimpairments,ifany,arecausedbythesebehaviors?Couldanyotherconditionbeabet-terexplanationforthebehaviors?Isthereevidenceofcoexistingprob-lemsordisorders?Onthebasisofthisinformation,theclinicianshouldbeabletoarriveatapreliminarydiagno
8 sis.OTHERDISORDERSIfsymptomsarisesuddenl
sis.OTHERDISORDERSIfsymptomsarisesuddenly,with-outanyprevioushistory,primarycarecliniciansshouldconsiderotherconditions,includingheadtrauma,physicalorsexualabuse,neurodegenerativedisorders,moodandanxietydisorders,sub-stanceabuse,oramajorpsycho-logicalstressinthefamilyorinschool,suchasbullying. Exit this guideline.Evaluate or refer, as appropriate.appropriate.Idenfy the child as CYSHCN if Yes Iftheevaluationidentiesorsug-geststhatanotherdisorderisthecauseoftheconcerningsignsandsymptoms,thenitisappropriatetoexitthisalgorithm.Theapproachinthatcaseisdictatedbytheresultsoftheevaluation.Ifareferralismade,theprimarycareclinicianshouldframethereferralquestionsclearlyandexpectthesereferralquestionstobeansweredinamannerthatwillensurethatacomanagementplanthataddressesthefamiliesandchilds/adolescentsongoingneedsforeducationandgeneralandspe-cialtyhealthcareisestablished.Re-sourcesfromtheAAPTaskForceonMentalHealthmightbehelpful.TYPICALORDEVELOPMENTAL Provide educaon addressing concern (eg, expectaons for aenon as a funcon of age)Enhanced Surveillance Apparently typical or developmental variation?Yes Evaluationmightrevealthatthechilds/adolescentsinattention,ac-tivitylevel,andimpulsivityarewithinthenormalrangeofdevelopment;mildlyorinconsistentlyelevatedincomparisontopeers;ornotassoci-atedwithanyfunctionalimpairmentinbehavior,academics,socialskills,orotherdomains.Itisimportantforthecliniciantoprobefurthertode-termineiftheparentalconcernsre-gardingthechild/adolescentareat-tributabletootherissuesinthefamily,suchasparentaltensionordrugabuseinanotherfamilymem-ber;whethertheyarecausedbyotherissuesinschool,suchassocialpressuresorbullying;orwhethertheyarewithinthespectrumoftypi-caldevelopment.Parenteducationaboutcontributionstotheircon-cernsandtothespectrumofdevel-opmentalvariationmightbehelpful.Educationabouttherangeoftypicaldevelopmentandstrategiesforim-provingachilds/adolescentsbe-haviorswhentheyareproblematicmightbehelpful.Ascheduleofen-hancedsurveillanceabsolvesthefamilyoftheneedtoreinitiatecon-tactifthesituationdeteriorates.Ifarecommendationforcontinuedrou-tinesystematicsurveillanceismade,thenassurancethatongoingcon-FROMTHEAMERICANACADEMYOFPEDIATRICS cernscanberevisitedinfuturepri-marycarevisitswouldbeimportant.INATTENTION,HYPERACTIVITY,AND/ORIMPULSIVITY(PROBLEMLEVEL):Children/adolescentswhosesymptomsdonotmeetthecriteriafordiagnosisofADHDmightstillencounterdifcultiesorimpairmentinsomesettings,asde-scribedintheDSM-PCChildandAdoles-centVersion.Professionalconsensusisthatmedica-tionisnotanappropriatetreatmentforchildren/adolescentswithinattention,hyperactivity,and/orimpulsivityprob-lemsthatdonotmeettheDSM-IV-TRcri-teriaforADHD.Children/adolescentswiththeseproblemsandtheirfamiliesmightbenetfromeducation,includingidentifyingandeliminatingtriggersthatpromptinattention,hyperactivity,orim-pulsivity;behavior-managementoptions,includingabehavior-therapyorparent-ingprogram;strategiesforimprovingschoolperformanceorbehavior;andtherecommendationsprovidedintheinat-tentionandhyperactivity/impulsivityclusterguidanceintheTaskForceonMentalHealthADHDtoolkit.Ifthechild/adolescentisfoundtomeettheDSM-IV-TRcriteriaforADHD,includ-ingcommensuratefunctionaldisabili-ties,suchdiagnosisshouldbemade,andprogressthroughtheprocess-of-careal-gorithmcontinuesasshown.ProvideEducationtotheFamilyandEducationforthefamilyandchild/adolescentaboutADHDisanimpor-tantelementinthecareplanwhenADHDisdiagnosedorinattention,hy-peractivity,and/orimpulsivity(prob-lemlevel)isidentied.Familyeduca-tioncontinuesthroughoutthecourseoftreatment.Itincludesan-ticipatoryguidanceinsuchareasastransitions(eg,fromelementarytomiddleandmiddletohighschoolsandfromhighschooltocollegeoremployment)andworkingwithschoolsanddevelopmentalchal-lengesthatmightbeaffectedbyADHD,includingdriving,gender,andFamilyeducationincludesallmem-bersofthefamily,includingdevelop-mentallyage-appropriateinformationfortheaffectedchild/adolescentandanysiblings.Topicsincludethedisor-der;thesymptoms;theassessmentprocess;commonlycoexistingdisor-ders;treatmentchoice
9 sandtheirap-plication,likelyeffects,ando
sandtheirap-plication,likelyeffects,andoutcomes;long-termimplications;impactonschoolperformance;andsocialAcriticalpieceofthetreatmentplanistoempowerchildren/adolescentstounderstandtheirconditionandthedegreeofimpairmentthatithasontheirdailylife,includingstrate-giesforaddressingsymptomsandimpairments.Ateverystage,thised-ucationmustcontinueinamannerconsistentwiththechilds/adoles-centsownlevelofunderstanding.Inaddition,itishelpfulforachild/ado-lescentwithADHDtoknowthenameofanymedicationthatheorshewillbeusingaswellascommonadverseTheissueofhowthepatientthinksofhimselforherselfisanotherareatoaddress;itshouldbeclariedthattheconditiondoesnotmeanthathe Inattention and/or hyperactivity/impulsivity problems not rising to DSM-IV DiagnosisProvide educaon of family and child re: concerns (eg, triggers for inaenon or hyperacvity) and behavior management strategies or schoolbased strategies Enhanced Apparently typical or developmental variation? Provide educaon to family and child re: concerns (eg, triggers for inaenon or hyperacvity) and behavior-management strategies or diagnosis of Coexisting conditions?Yes SupplementalAppendixPEDIATRICSVolume,Number, orsheislesssmartthanotherchil-dren/adolescents.Itcanalsobehelpfultoidentifyandsupportareasofstrengthandhelpthechild/ado-lescentwithADHDtolearnhowtoidentifywhenheorsheneedshelpandhowtoprocureit.Educationforparentsshouldincludeproactivestrategiesthatcanhelpmakethehomeenvironmentmorefacilitativefortheirchild/adolescentwithADHD.Forexample,makingad-aptationsandprovidingstructurethatenablesthechild/adolescenttobestusehisorherstrengthsandcompensatefordecitscanbehelp-fultoparents.Suchstrategiesin-cludeprovidinggreaterconsistencyintheparentsbehaviortowardtheirchild/adolescentwithADHD,formingdailyroutinesandschedules,anddisplayinghouserulesinprominentplacesasvisualreminders.Itmayhelpparentstocommunicateabouttheirchilds/adolescentsbehaviorandeachparentsresponseaswellastheparentaldivisionoflabor.Itisalsoimportanttocheckonthepar-entswell-being,becauseparentsofchildren/adolescentswithADHDfre-quentlyareunderstressandmightnottakeintoconsiderationtheirownwell-beingorthatofotherfamilymembers.Theseconcernsarepar-ticularlyrelevantwhenaparentalsohasADHDorassociatedconditions.Parentswilllikelybenetiftheylearnaboutoptimalwaystopartnerwithschoolssuchthatteacherscanbe-comepartoftheeducationalandinter-ventionteams.Parentswillbenetfrombeinginformedaboutschoolser-vicesthatareavailabletoaddresstheirchilds/adolescentsneeds,in-cludingtheIndividualsWithDisabili-tiesEducationAct(IDEA)andtheReha-bilitationAct(504)servicesprovidedbytheirstate,andtheeligibilityre-quirementsforthem.Withaparentspermission,thecliniciancanprovidetheschoolwithinformationfromtheevaluationthatwillhelptheschoolde-termineeligibilityforspecialeduca-tionservicesanddevelopappropriateadaptations.AdvocacyandsupportgroupssuchasCHADD(ChildrenandAdultsWithAttention-Decit/Hyperac-tivityDisorder)canalsoprovideinfor-mationandsupporttofamilies.TheADHDtoolkitprovideslistsofed-ucationalresourcesincludingWeb-basedresources,organizations,andbooksthatmightbeusefultoparentsandstudents.COEXISTINGCONDITIONS:Ifotherdisordersaresuspectedorde-tectedduringthediagnosticevalua-tion,anassessmentoftheurgencyoftheseconditionsandtheirimpactontheADHDtreatmentplanneedstobeUrgentconditions,suchassuicidalthoughtsoractsorotherbehaviorswiththepotentialtoseverelyinjurethechild/adolescentorotherpeo-ple,suchasseveretemperout-burstsorchildabuse,shouldbead-dressedimmediatelywithservicescapableofhandlingcrisisTheevidenceshowsthatcoexistingconditions,suchasoppositionalityandanxiety,mightimprovewithtreatmentofADHD.Forexample,childrenwithADHDandcoexistinganxietydisordersmightndthatADHDmedicationsde-creaseanxietysymptomsaswellasADHDbehaviors.Inthecasesofseverelearningdisordersoroppositionalde-antdisorder,atrialoftreatmentforADHDmightindicatewhethertheap-parentcoexistingconditioncanbemodulatedwithtreatmentoftheADHD.Otherpatientsmightrequireaddi-tionaltherapeutictreatments,suchascognitivebehavioraltherapyoradif-
10 ferentoradditionalmedication,toad-equate
ferentoradditionalmedication,toad-equatelytreattheADHDandcoexistingUntreatedsubstanceusedisorderneedstobeaddressedrstbeforefullyaddressingthepatientsADHDIftheprimarycareclinicianrequirestheadviceofanothersubspecialist,thentheclinicianshouldconsidercarefullywhentoinitiatetreatmentforADHD.Insomecases,itmightbeadvis-abletodelaythestartofmedicationuntiltheroleofeachmemberofthetreatmentteamisestablished.Forex-ample,withsomecoexistingpsychiat-ricdisorders,suchassevereanxiety,depression,andbipolardisorder,aco-managingdevelopmentalbehavioralpediatricianorpsychiatristmighttake Assess impact on treatment planFurther evaluation/referral as needed Coexisting disorders preclude primary care Follow-up and establish co-management planSee TFOMH AlgorithmsYes Provide educaon to family and child re: concerns (eg, triggers for inaenon or hyperacvity) and behavior-management strategies or Yes diagnosis of ADHD? Coexisting conditions? Yes FROMTHEAMERICANACADEMYOFPEDIATRICS responsibilityfortreatmentofboththeADHDandthecoexistingillness.Atothertimes,suchasinthecaseofachildoradolescentwithcoexistingmilddepressionorobsessive-compulsivedisorder,amentalhealthclinician,developmental-behavioralpediatrician,neurodevelopmentaldis-abilityclinician,orchildneurologistmaytreatthecoexistingconditionwhiletheprimarycareclinicianover-seesthetreatmentforADHD,ortheconsultingphysicianmayadvisetheprimarycarephysicianaboutthetreatmentofthecoexistingconditiontotheextentthattheprimarycarephy-sicianiscomfortabletreatingboththeADHDandcoexistingproblems. ESTABLISH MANAGEMENT TEAM Identify child as CYSHCN Establish team including coordination plan Collaborate with family, school, and child to identify target goals. IDENTIFYASACHILD/YOUTHWITHSPECIALHEALTHCARENEEDS:AnychildwhomeetsthecriteriaforADHDshouldbeconsideredachild/youthwithspecialhealthcareneeds.TheAAPencouragesclinicianstode-velopsystemsthatensurethatthemedicalhomeneedsofallchildren/youthwithchronicillnessesaremet.Theseneedsandstrategiesformeetingthemarediscussedinfur-therdetailelsewhereinthisguidelineandinotherAAPresourcessuchasTheBuildingYourMedicalHomeTool-AddressingMentalHealthCon-cernsinPrimaryCare:ACliniciansManagementIssuesQuestionsthatareimportanttocon-siderindevelopingamanagementplanincludethefollowing:Doesthefamilyneedfurtherassis-tanceinunderstandingthecoresymptomsofADHDandtheirchilds/adolescentstargetsymptomsandcoexistingconditions?Doesthefamilyneedsupportinlearninghowtoestablish,measure,andmonitortargetgoals?Havethefamilysgoalsbeenidenti-edandaddressedinthecareplan?Doesthefamilyhaveanunderstand-ingofeffectivebehavior-managementtechniquesforre-spondingtotantrums,oppositionalbehavior,orpoorcompliancetore-questsandcommands?Ishelpneededfornormalizingpeerandfamilyrelationships?Doesthechild/adolescentneedhelpinacademicareas?Ifso,hasafor-malevaluationbeenperformedandreviewedtodistinguishworkpro-ductionproblemssecondarytoADHDfromcoexistinglearningorlanguagedisabilities?Doesthechild/adolescentneedhelpinachievingindependenceinself-helporschoolworkproduction?Doesthechild/adolescentorfamilyrequirehelpwithoptimizing,orga-nizing,planning,ormanagingschoolworkow?Doesthefamilyneedhelpinrecog-nition,understanding,ormanage-mentofcoexistingconditions?Isthereaplaninplacetosystemat-icallyeducatethechild/adolescentaboutADHDanditstreatmentaswellasthechilds/adolescentsownstrengthsandweaknesses?Isthereaplaninplacetoempowerthechild/adolescentwiththeknowl-edgeandunderstandingthatwillin-creasehisorheradherencetotreatments,andhasthatbegunasearlyaspossibleandbeenad-dressedatthechilds/adolescentsdevelopmentallevel?Doesthefamilyhaveacopyofacareplanthatsummarizesndingsandtreatmentrecommendationsthatcanbeupdatedandusedinschoolsettingsandotherprofessionalset-tingssothatthehistoryandtreat-mentplandoesnotneedtobecon-stantlyreinvented?Isthefollow-upplansufcienttoprovidecomprehensive,coordi-nated,family-centered,culturallycompetent,ongoingcare?COLLABORATEWITHTHEFAMILY,SCHOOL,ANDCHILD/ADOLESCENTTOIDENTIFYTARGETGOALS:Whereasaninitialstimulantmedica-tiontrialmightf
11 ocusonnormalizingcoresymptomsofADHD,alon
ocusonnormalizingcoresymptomsofADHD,alonger-termcomprehensiveplanshouldfocusonidentifyingandaddressingindividual-izedandspecicbehavioral,academic,andsocialtargetgoalsandtreat-ments.Theclinicianshouldassistpar-ents,teachers,otherinformants,andthechild/adolescentindevelopingtar-getgoalsintheareasoffunctionmostcommonlyaffectedbyADHD:academ-ics;peer,parent,orsiblingrelation-ships;andsafetyinthecommunity.Othergoalsmightbeidentiedbyus-ingtheInternationalClassicationofFunction(ICF)analysisconductedinthediagnosticphaseoftheclinicalItisnotnecessarytodevelopgoalsineveryareaallatonce.Familiesmightbeencouragedtoidentifyupto3ofthemostimpairingareasonwhichtheywillinitiallywork;parentsandthechild/adolescentcanthenaddothertargetsasindicatedbytheirrelativeimportance.Suchanexercisewillfacil-itategreaterunderstandingoftheef-fectsofthedisorderoneachmemberofthefamilyandmightleadtoanim-provedcollaborationinthedevelop-mentofafewspecicandmeasurableoutcomes.Itishelpfultoincorporatethechilds/adolescentsstrengthsandresilientfactorsinconsideringtargetgoalsandingeneratingatreatmentplan.Goalsfortheschoolrequireinputfromtheteachersintermsofbothidenticationandmeasurement.SupplementalAppendixPEDIATRICSVolume,Number, Establishingmeasurablegoalsinin-terpersonaldomainsandbehaviorinunstructuredsettingsmightbepartic-ularlyimportant.Wheneverpossible,itisimportanttomakeprogresscount-able.Forbehaviorssuchasfre-quencyofyellingorfrequencyofmissingassignments,chartsmaybesuggestedasstrategiesforrecordingtheeventsothatparents,teachers,thechild/adolescent,andclinicianscanallagreeonhowmuchprogresshasbeenmade.Inthisway,successescanbebuiltoninasystematicway.Suchstrategiescanhelpafamilyaccuratelyassessandseeprogressofbehaviorchanges.Adailysingle-pagereportcardcanbeusedtoidentifyandmoni-tor4or5behaviorsthataffectfunctionatschool,andthesereportscanbesharedwiththeparents.Otherstrate-giesandtoolsareavailabletoclini-ciansintheAAPADHDtoolkitandtoparentsinthebookADHD:WhatEveryParentNeedstoKnowAstreatmentproceeds,inadditiontousingaDSM-IV-TR basedADHDratingscaletomonitorcoresymptomchanges,formalandinformalqueriescanbemadeintheareasoffunctionmostcommonlyaffectedbyADHD(eg,academicachievement;peer,parent,orsiblingrelationships;andsafetyinthecommunity).Progresscanalsobemonitoredbydeterminingprogressonthetargetgoals.Ateveryvisit,itishelpfultograduallyempowerchil-dren/adolescentstobecomefullpart-nersintheirtreatmentplanbyadoles-cence.Informationfromtheschool,includingADHDsymptoms(ratingscalecompletedbytheteacher),grades,andanyotherformaltestingresults,arealsohelpfulatthesevisits.ESTABLISHTEAMANDCOORDINATIONPLAN:Itisbestforthetreatmentteamtoin-cludeeveryoneinvolvedinthecareofthechild/adolescent:thechild/adoles-cent,parents,teachers,theprimarycareclinician,therapists,subspecial-ists,andotheradults(suchascoachesorreligiousleaders)whowillbeac-tivelyengagedinsupportingandmon-itoringthetreatmentofADHD.Itishelpfulfortheprimarycareclinicianoranassignedcarecoordinatortoensurethateachteammemberisawareofhisorherroleandthatbothroutineandas-neededcommunicationstrategiesandexpectationsforre-ports(frequency,scope)areclear.Col-laborationwiththeschoolgoesbe-yondtheinitialreportofdiagnosisandisbestfacilitatedbyagreementonastandardized,reliablesystemforex-changingcommunications.Thistreatmentoptionisrestrictedtochildren/adolescentswhomeetthedi-agnosticcriteriaforADHD.Althoughitisarareoccurrenceandmoreevidenceisrequiredtoidentifywhetheritisanincreasedrisk,itisimportanttoobtainacarefulhistoryofcardiacsymp-toms;acardiacfamilyhistory,par-ticularlyofarrhythmias,suddendeath,anddeathatayoungagefromcardiacconditions;andvitalsigns,cardiacphysicalexamina-tion,andfurtherevaluationonthebasisofclinicaljudgment.Stimulantmedicationsandseveralnonstimulantmedicationsarenowavailable,asoutlinedinTable3.ThepresenceofaticdisordermightaffectthedecisionaboutwhichmedicationtoinitiateforADHDther-apy.WiththegreateravailabilityofmedicationsapprovedbytheFDAforchildren/adolescentswithADHD,ithasbecomeincreasinglyunlikelythatclini-ciansneedtoconsidertheoff-labeluseof
12 othermedications.Thechoiceoffor-mulation
othermedications.Thechoiceoffor-mulationdependsonfactorssuchastheefcacyofeachagentforagivenchild/adolescent,thepreferredlengthofcoveragetime,whetherachildcanswallowpillsorcapsules,andex-pense.Theextended-releaseformula-tionsaregenerallymoreexpensivethantheimmediate-releaseformula-tionsbutmightbepreferredbymanyfamiliesandchildren/adolescents,be-causetheyprovidethebenetsofcon-sistentandsustainedcoveragewithfeweradministrationsperday.Long-actingformulationsusuallyprecludetheneedforschool-basedadministra-tionofADHDmedication.Bettercover-agewithfeweradministrationsleadstogreaterconvenienceforthefamilyand,therefore,mightalsoleadtobet-teradherencetothemedicationman-agementplan.Somepatients,particu-larlysomeadolescents,mightrequiremorethan12hoursofcoveragetoen-sureadequatefocusandconcentra-tionduringeveningstudytimeanddriving;inthesecases,ashort-actingpreparationmightbeusedinadditiontoalong-actingpreparation.Theeasewithwhichpreparationscanbeadministeredandtheminimizationofadverseeffectsareimportantforthequality-of-lifeconcernsthatchil-dren,youth,andparentsexpressaroundthedecisiontousemedication. Opon: Medicaon(ADHD only and past medical or family history of cardiovascular disease considered) Iniate treatment Titrate to maximum benet, minimum adverse eects Monitor target outcomes Opon: Behavior management (developmental variaon, problem or ADHD) Idenfy service or approach Monitor target outcomes Opon: Collaborate with school to enhance supports and services (developmental variaon, problem, or ADHD) Idenfy changes Monitor target outcomesSee action statement 5See action statement 6BEGIN TREATMENT FROMTHEAMERICANACADEMYOFPEDIATRICS Othercontextissuesthatshouldalsobeconsideredindecidingwhichmed-icationtorecommendincludethetimeofdaywhenthetargetedsymptomsoccur,whenhomeworkisusuallydone,whethermedicationremainsac-tivewhenteenagersaredriving,whethermedicationalterssleepinitia-tion,andriskstatusfordruguse.Allapprovedstimulantmedicationsaremethylphenidateoramphetaminecompounds,whichhavesimilareffectsandadverseeffects.Giventheexten-siveevidenceofefcacyandsafety,theyremaintherstchoiceofmedica-tiontreatment.Thus,thedecisionre-gardingwhichcompoundaclinicianrstprescribesshouldbemadeonthebasisofindividualpreferencesoftheclinicianandfamily.Somechildren/ad-olescentswillrespondbettertoordis-playmoreadverseeffectswith1com-poundgrouportheother.Becausetheseeffectscannotbedeterminedinadvance,ifatrialwith1groupisun-successful(poorefcacyoradverseeffects),atrialonamedicationfromtheothergroupshouldbeundertaken.Forcasesinwhichthereisconcernaboutpossibleabuseordiversionofthemedicationorthereisastrongfamilypreferenceagainststimulantmedication,anFDA-approvednon-stimulantmedicationmaybeconsid-eredastherstchoiceofmedication.Themedicationsthatuseamicrobeadtechnologycanbeopenedandsprin-kledonfoodforpatientswhohavedif-cultyswallowingtabletsorcapsules.Immediate-releasemethylphenidate,whichcomesinliquidandchewableforms,andamethylphenidatetrans-dermalpatcharealsoavailableasal-ternativestotabletsorcapsules.Itishelpfultopreparefamiliesfortheinitialmedication(titration)process,includingwhatitwillentailandhowlongitmighttake.Theusualprocedureistobeginwithalowdoseofmedica-tionandtothedosethatpro-videsmaximumbenetandminimaladverseeffects.Initially,coresymp-tomreductionismorelikelytoindicatemedicationeffects;theeffectsofim-SUPPLEMENTALTABLE3FDA-ApprovedMedications:DosingandPharmacokinetics MedicationBrandInitialTitrationDoseFrequencyTimetoInitialEffectDuration,hMaximumDoseAvailableDosesMixedamphetamine2.5 5.0mgQD BID20 60min640mg5.0-,7.5-,10.0-,12.5-,15.0-,20.0-,and30.0-mgtabletsAdderallXR5mgQD20 60min1040mg5-,10-,15-,20-,25-,and30-mgDextroamphetamineDexedrine2.5mgBID TID20 60min4 640mg5-and10-mg(Dextrostatonly)5mgQD BID60min640mg5-,10-,and15-mgcapsulesLisdexamfetamineVyvanse20mgQD60min10 1270mg20-,30-,40-,50-,60-,and70-mgcapsulesMethylphenidateConcerta18mgQD20 60min1254mg(13y);72mg(13y)18-,27-,36-,and54-mgMethylER10mgQD20 60min860mg10-and20-mgtabletsMethylin5mgBID TID20 60min3 560mg5-,10-,and20-m
13 gtabletsandliquidandchewableformsDaytran
gtabletsandliquidandchewableformsDaytrana10mgApplyfor9h60min11 1230mg10-,15-,20-,and30-mg5mgBID TID20 60min3 560mg5-,10-,and20-mgtabletsRitalinLA20mgQD20 60min6 860mg20-,30-,and40-mgcapsulesRitalinSR20mgQD BID1 3h2 660mg20-mgcapsulesMetadateCD20mgQD20 60min6 860mg10-,20-,30-,40-,50-,and60-mgcapsulesDexmethylphenidateFocalin2.5mgBID20 60min3 520mg2.5-,5.0-,and10.0-mgtabletsFocalinXR5mgQD20 60min8 1230mg5-,10-,15-,and20-mgAtomoxetineStrattera0.5mg/kgperd,thenincreaseto1.2mg/kgperd;40mg/dforadultsandchildrenat154lb,upto100mg/dQD BID1 2wkAtleast10 12h1.4mg/kg10-,18-,25-,40-,60-,80-,and100-mgcapsulesIntuniv1mg/dQD1 2wkAtleast10 12h4mg/d1-,2-,3-,and4-mgtabletsKapvay0.1mg/dQD BID1 2wkAtleast10 12h0.4mg/d0.1-and0.2-mgtabletsQDindicatesdaily;BID,twicedaily;TID,threetimesdaily.Availableinagenericform.Dosagesforthedermalpatcharenotequivalenttothoseoftheoralpreparations.SupplementalAppendixPEDIATRICSVolume,Number, provementinfunctionrequireamoreextendedtimeperiod.Stimulantmedi-cationscanbeeffectivelytitratedona3-to7-daybasis.Duringtherstmonthoftreatment,medicationdosemaybetitratedwithaweeklyorbiweeklytele-phonecalltothefamily.Theincreasingdosescanbeprovidedeitherbypre-scriptionsthatallowdoseadjust-mentsupwardor,forsomeofthemed-ications,by1prescriptionoftablets/capsulesofthesamestrengthwithinstructionstoadministerprogres-sivelyhigheramountsbydoublingortriplingtheinitialdose.Anotherap-proachsimilartothatusedintheMTAisforparentstobedirectedtoadministerdifferentdosesofthesamepreparation,eachfor1weekatatime(eg,SaturdaythroughFriday).Attheendofeachweek,teacherandparentfeedbackand/orDSM-IV-TR basedADHDratingscalescanbecompletedthroughatelephoneinterview,fax,orsecureelectronicsystem.InadditiontotheADHDratingscale,parentsandteachersshouldbeaskedtoreviewad-verseeffectsandtargetgoals.Aface-tofacefollow-upvisitisrecom-mendedbythefourthweekofmedica-tion,duringwhichcliniciansreviewtheresponsestothevaryingdosesandmonitoradverseeffects,pulse,bloodpressure,andweight.Toensurethatprogressinsymptomcontrolisbeingmaintained,cliniciansshouldcontinuetomonitorlevelsofcoresymptomsandimprovementinspeciedtargetgoals.Ageneralguideforvisitstotheprimarycareclinicianisforthefacetofacevisitstooccurinitiallyonamonthlybasis,untilthereisaconsis-tentoptimalresponse,andthenevery3monthsintherstyearoftreatment.Subsequentvisitswilldependontheresponsebutshouldoccuratleast2timesperyear,untilitisclearthattar-getgoalsareprogressingandstable,andthenperiodicallyasdeterminedbythefamilyandtheclinician.Recentre-sultsfromtheMTAstudyindicatethatthereareanumberofchildren/adoles-centswho,by3yearsafterstartingmedication,continuetoimproveevenifthemedicationhasbeendiscontin-Thendingssuggestthatchil-dren/adolescentswhoarestableintheirimprovementofADHDsymptomsmaybegivenatrialoffmedicationaf-terseveralyearstodetermineifmed-icationisstillneeded.Thisprocessisbestundertakenwithclosemonitoringofthechilds/adolescentscoresymp-tomsandfunctionathome,inschool,andinthecommunity.Wheneverpossible,improvementsincoresymptomsandtargetgoalsshouldbemonitoredinanobjectiveway(eg,goingfrom60%to20%miss-ingassignmentsperweek[seetheADHDtoolkit]),andthecoresymp-tomscanbemonitoredbyuseofoneoftheDSM-IV-TR basedADHDratingscalessuchastheVanderbiltADHDfollow-upscales.Cliniciansareen-couragedtoeducateparentsthatal-thoughmedicationcanbeeffectiveinfacilitatingschoolworkproduc-tion,ithasnotbeenshowntobeef-fectiveinaddressinglearningdis-abilities.Achild/adolescentwhocontinuestoexperienceacademicunderachievementafterattainingsomecontrolofADHDbehavioralsymptomsshouldbeassessedforacoexistingcondition,includinglearn-ingandlanguagedisabilities,othermentalhealthdisorders,orotherpsychosocialstressors.Noncompli-ancewiththetreatmentplanshouldalsobeassessed.Ifthemaximumdoseofastimulantpreparationisreachedandless-than-satisfactoryresultshavebeenachievedorintolerableadverseef-fectsoccurbeforeadequateefcacywithamedicationfromoneofthestimulantgroups(methylphenidateoramphetamine),amedicationfromtheotherstimulantgroupshouldberecommendedwithasimilartitra-tionplan.Atleasthalfofth
14 echil-dren/adolescentswhosesymptomsfailt
echil-dren/adolescentswhosesymptomsfailtorespondto1stimulantmedi-cationmayhaveapositiveresponsetothealternativemedication.Familiesconcernedabouttheuseofstimulantsorwithconcernsaboutabuseordiversionmaychoosetostartwithatomoxetineorextended-releaseguanfacineorextended-releaseclonidine.Inaddition,thosewhosesymptomsdonotrespondtoeitherstimulantgroupmightstillre-spondtoatomoxetineorextended-releaseguanfacineorextended-releaseclonidine.Extendedreleaseguanfacineorextendedreleaseclo-nidinealsomaybeaddedasanad-junctivetherapyinchildrenwhopar-tiallyrespondtostimulantThereisablock-boxwarningonatomoxetineofthepossibilityofsuicidalideationwheninitiatingmedicationmanagement.Earlysymptomsofsuicidalideationmightincludethinkingaboutself-harmandincreasingagitation.Ifthereareanyconcernsaboutsui-cidalideationinchildrenpre-scribedatomoxetine,furtherevalu-ation,reconsiderationabouttheuseofatomoxetine,andmorefre-quentmonitoringshouldbeconsid-ered,andifnecessary,referraltoamentalhealthclinicianshouldbeAtomoxetineisaselectivenorepinephrine-reuptakeinhibitorandmightresultinmaximumre-sponseonlyafterapproximately4to6weeks.Extended-releaseguanfacineandextended-releaseclonidineareA-adrenergicagonistsandmightresultinmaximumresponseinapproxi-mately2to4weeks.Parentsmaybeencouragedtocompleteweeklysymp-tomandadverse-effectmonitoring,asFROMTHEAMERICANACADEMYOFPEDIATRICS describedpreviously,asanobjectivemeasuretomonitorefcacy.BecausesymptomchangeismoregradualwithatomoxetineandA-adrenergicagoniststhanwithstimulantmedications,familieswhohavehadpreviousexpe-riencewithstimulantsshouldbemadeawareofthisfact.Insomepatients,amodesteffectofatomoxetinemightbeseenin1week.Atomoxetinemightcausegastrointestinaltractsymptomsandsedationearlyintreatment,soitisrecommendedtoprescribehalfthetreatmentdose(0.5mg/kg)fortherstweek.Appetitesuppressioncanalsooccur.BothAagonistscancausetheadverseeffectofsomno-lence.Inaddition,itisrecommendedthatthemedicationsbetaperedwhendiscontinuedtopreventapossiblere-boundinbloodpressure.SpecialCircumstances:Preschool-AgedChildrenCliniciansshouldinitiateADHDtreat-mentofpreschool-agedchildren(4 5yearsofage)withbehaviortherapyandshouldalsoassessforotherdevelopmentalproblems,es-peciallywithlanguage.Ifchildrendonotexperienceadequatesymptomandfunctionalimprovementwithbe-haviortherapy(mostprogramsare10 14weekslong,buttheclinicianshouldcheckwiththetherapistsabouttheirusuallengthofinterven-tion),theclinicianshouldrstevalu-atetheadequacyandparentalac-ceptanceofthetherapy.Ifthesymptomsand/orfunctioninghavenotimprovedandthechildisatsig-nicantbehavioralordevelopmentalriskbecauseofADHD,medicationcanbeprescribed,asdescribedpre-viously.Itmustbenotedthat,cur-rently,theFDAhasonlyapproveddextroamphetamineforADHDinchil-dreninthisagegroup,althoughthereislittleevidencetosupportitssafetyandefcacy.Thereis,how-ever,evidencethatmethylphenidateissafeandefcaciousforchildreninthisagegroup.thattherateofmetabolizingmethyl-phenidateisslowerinchildren4and5yearsofage,sotheyshouldbestartedatalowerdosethatisin-creasedinsmallerincrements.Inad-dition,thepreschool-agedchildrenstudiedinthemultisitestudymoreseveredysfunction,whichshouldbeconsideredinthedecisiontotrytreatmentwithmethylpheni-date.Theadditionalcriteriaforde-ningmoderate-to-severeimpair-mentincludesymptomspresentforatleast9monthsandclearimpair-mentinboththehomeanddaycare/preschoolsettingsthathasnotre-spondedtoanappropriatebehavioralintervention.Limitedevi-andnoFDAapprovalforchil-dreninthisagegroupareavailableforatomoxetine,andnoevidenceorapprovalforextended-releaseguan-facineorextended-releaseclonidineareavailable.SpecialCircumstances:AdolescentsCliniciansshouldassessadolescentpatientswithADHDforsymptomsofsubstanceuseorabusebeforebegin-ningmedicationtreatment.Ifsub-stanceabuseisrevealed,theyshouldhavethepatientstoptheuse,andtheyshouldprovidetreatmentorreferfortreatmentforsubstanceabusebeforebeginningtreatmentforADHD.Clini-ciansarealsoencouragedtomonitorsymptomsandprescriptionrellsforsignsofmisuseordiversionofADHDSpecialconcernshouldbetakentoprovidemedicationco
15 verageforADHDsymptomcontrolwhiledriving.
verageforADHDsymptomcontrolwhiledriving.Longer-actingorlate-afternoon/short-actingmedicationsmightbehelpfulinthisregard.Counselingforadolescentsaroundmedicationis-suesshouldincludedealingwithre-sistancetotreatmentandempower-ingchildren/adolescentstotakechargeofandowntheirmedicationmanagementasmuchaspossible.Techniquesofmotivationalinter-viewingmightbeusefulinimprovingSpecialCircumstances:FamiliesandChildren/AdolescentsWhoDeclineThedecisionaboutwhatisthemostacceptabletreatmentfortheirchild/adolescentrestswiththefamily,andtheclinicianmustrespectthatdeci-sion.Theclinicianshould,however,ad-dressanymisinformationorconcernsaboutmedicationsharedbythefamily,encourageallotherdimensionsoftreatment,andprovideappropriateSpecialCircumstances:InattentionorHyperactivity/Impulsivity(ProblemMedicationisappropriateforchil-dren/adolescentswhosesymptomsdonotmeetDSM-IV-TRcriteriafordiagno-sisofADHD.BehaviorManagementEvidence-basedparenttrainingtypi-callybeginswith7to12weeklygroupsessionswithatrainedtherapistorcertiedinstructor.ThefocusisonparenteducationaboutADHD,thechilds/adolescentsbehaviorprob-lems,anddifcultiesinfamilyrelation-ships.Atypicalprogramaimstoim-provetheparents/caregiversunderstandingofthechilds/adoles-centsbehaviorandtoteachthemskillstohelpthechild/adolescenttoreducethebehavioraldifcultiesposedbyADHD.Programsofferspecictechniquesforreinforcingadaptiveandpositivebe-haviorsanddecreasingoreliminatinginappropriatebehaviors,bothofwhichalterthemotivationofthechild/adolescenttocontrolattention,activ-ity,andimpulsivity.TheseprogramsSupplementalAppendixPEDIATRICSVolume,Number, emphasizeestablishingpositiveinter-actionsbetweenparentsandchildren;learninghowtoshapechildrensbe-haviorsthroughcombinationsofpraisingandignoring;howtogivesuc-cessfulcommands;howtoreinforcepositivebehaviors;howtoextinguishinappropriatebehaviorsthroughig-noring;howtoidentifywhichbehav-iorsarehandledmostappropriatelythroughpunishment;anddetermininghowtocarrypunishmentsoutinare-sponsibleway.Theseprogramsallem-phasizeteachingself-controlandbuildingpositivefamilyrelationships.Ifparentsstronglydisagreeaboutbe-haviormanagementorhaveconten-tiousrelationships,parentingpro-gramswilllikelybeunsuccessful.Otherstrategies,suchaschangingthephysicalenvironmenttoreducestim-ulitooveractivity,arealsoeffectivebychangingthestimulithattriggerprob-lembehaviors.Dependingonthese-verityofthechilds/adolescentsbe-haviorsandthecapabilitiesoftheparents,grouporindividualtrainingprogramswillberequired.Programstypicallyincludesupportformainte-nanceandrelapseprevention.Behaviortherapyshouldbedifferenti-atedfrompsychologicalinterventionsdirectedtothechild/adolescentanddesignedtochangethechilds/adoles-centsemotionalstatus(eg,playther-apy)orthoughtpatterns(eg,interper-sonaltalktherapy).ThesepsychologicalinterventionsdonothaveademonstratedefcacyfortheADHDcoresymptoms,andgainsachievedinthetreatmentsettingusu-allydonottransferintotheclassroomorhome.Bycontrast,parenttraininginbehaviortherapyandclassroombe-haviorinterventionshavesuccessfullychangedthebehaviorofchildren/ado-lescentswithADHD.Behaviortherapyisalsoapplicableforchildren/adoles-centswhohaveproblemsinthedo-mainsofinattentionorhypersensitivi-ty/impulsivitybutdonotmeettheDSM-IV-TRcriteriaandforthosechildren/adolescentswithadevelopmentalUnlessprimarycarecliniciansarespecicallytrained,havetrainedstafforacolocatedtherapist,ordedicatemanyvisitstoprovidingtheongoingtreatment,theymightnotbeeffectiveinprovidingbehaviortherapy.ciansmightalsohavedifcultiesde-terminingtheskillsofbehaviorthera-pistslistedinthebehavioralhealthinsuranceplan.Thisdeterminationisimportant,becausemanytherapistsfocusonaplayorinterpersonal-talktherapythathasnotbeenshowntobeeffectiveintreatingthecoresymp-tomsofADHD.Telephoneinquiriesoftherapists,agencies,andmentalhealthcliniciansregardingtheirap-proachtobehaviortherapymightal-lowclinicianstodeveloparesourcelistforparents.Cliniciansmightalsorequestreferencesfromotherpar-entsofchildren/adolescentswithADHD,professionalorganizations(eg,AssociationforBehaviorandC
16 ognitiveTherapies),andADHDadvo-cacyorgan
ognitiveTherapies),andADHDadvo-cacyorganizations(eg,CHADD).Par-entswhohavereadauthoritativelywrittenbooksaboutbehaviorthera-py/behaviorparenttrainingmightbeinabetterpositiontoknowwhattheyarelookingforinatherapistandaskthesalientquestionswhenseekingappropriatetherapists.Someoftheseresourcesareavail-ableintheADHDtoolkitandtheADHD:WhatEveryParentNeedstoKnowClassroombehaviormanagementalsofocusesonshapingthechilds/adoles-centsbehaviorsandmaybeinte-gratedintoclassroomroutinesforallstudentsortargetedforaselectedchild/adolescentintheclassroom.Classroommanagementoftenbeginswithincreasingthestructureofactivi-ties.Tokeneconomyreferstousingpointsortokensthataregivenforpos-itivebehaviors,andresponsecostre-ferstopointsortokenssubtractedforinappropriatebehaviors.Thetokensorpointscanthenbecashedinafteradenedperiodforrewardsorprivi-leges.Systematicrewards(eg,useofatokeneconomy)areincludedtoin-creaseappropriatebehaviorandelim-inateinappropriatebehavior.Aperi-odic(oftendaily)behaviorreportcardcanrecordthechilds/adolescentsprogressorperformancewithregardtogoalsandcommunicatethechilds/adolescentsprogresstotheparents,whothenprovidereinforcersorcon-sequencesbasedonthatdaysperfor-mance.Suchprogramsarealsousefulforthepurposeofmonitoringmedica-tioneffects.COLLABORATEWITHTHESCHOOLTOENHANCESUPPORTSANDSERVICESManyteachersandschoolshaveeffec-tivestrategiesforsupportingandservingchildren/adolescentswithADHD.Schoolscanimplementbehavior-managementprogramsthatdirectlytargetADHDsymptomsaswellasinterventionstoenhanceacademicandsocialfunctioning.Schoolsmayalsousestrategies(eg,dailybehaviorreportcards)toenhancecommunica-tionwithfamilies.Allschoolsshouldhavespecialists(eg,schoolpsycholo-gists,counselors,specialeducators)whoobservethechild/adolescent,identifytriggersandreinforcers,andsupportteachersinchangingthecir-cumstancesoftheclassroomandmakingaccommodationstoaddressADHDsymptoms,suchaswritten-outputbypassstrategies,untimedtesting,testinginlessdistractingenvi-ronments,preferentialseating,androutinereminders.Cliniciansshouldbeawareoftheeligi-bilitycriteriaforthe504RehabilitationActandtheIndividualsWithDisabilitiesEducationActsupportsintheirstateFROMTHEAMERICANACADEMYOFPEDIATRICS andlocalschooldistrict(s)shouldunderstandtheprocessforre-ferralaswellastheindividualswithwhomthephysicianorparentshouldmakecontact.Thisinformationcanbeprovidedtoparentstosupporttheireffortstorequestclassroomadapta-tionsfortheirchild/adolescentwithADHD,includingtheuseofempiricallysupportedacademicinterventionstoaddressachievementdifcultiesasso-ciatedwithADHDsymptoms. symptoms improve? Inprovidingamedicalhome,primarycarecliniciansshouldregularlymoni-aspectsofADHDtreatment,tosystematicreassessmentofsymptomsandfunctionregularreassessmentofassurancethatthefamilyisedwiththecaretheyarereceiv-ingfromothercliniciansandthera-pists,ifapplicable;provisionofanticipatoryguid-,furtherandfamilyeducation,andtransi-tionplanningasneededandassurancethatcarecoordinationisoccurringandmeetingtheneedsofthechild/adolescentandfamily;conrmationoftoanyprescribedmedicationregimen,withadjustmentsmadeasneeded;heartrate,bloodpressure,height,andweightmonitoring;andcontinuingtoformatherapeuticre-lationshipwiththechild/adolescentandempowerfamiliesandchil-dren/adolescentstobestrong,in-formedadvocates.Sometreatmentmonitoringcanoccurduringgeneralhealthcarevisitsiftheclinicianinquiresaboutprogressto-wardtargetgoals,adherencetomedi-cationandbehaviortherapy,con-cerns,orchanges.Monitoringofchildren/adolescentswithinattentionorhyperactivity/im-pulsivityproblemscanhelptoensureprompttreatment,shouldtheirsymp-tomsworsentotheextentthatadiag-nosisofADHDiswarranted. Reevaluate to confirm diagnosis and/or provide education to improve adherence.Reconsider treatment plan including changing of the medication or dose, adding a medication approved for adjuvant therapy, and/or changing behavioral therapy. ADHDtreatmentfailuremightbeasignofincorrectorincompletediagnosis.Cliniciansareadvisedtorepeatthefulldiagnosticevaluationandpayin-creasedattentiontothepossibilityofcoexis
17 tingconditionsthatmimicorareassociatedwi
tingconditionsthatmimicorareassociatedwithADHD,suchassleepdisorders,Aspergersyndrome,orepilepsy(eg,absenceepilepsyorpartialseizures).Acoexistinglearningdisordermightalsocauseanapparenttreatmentfailure.Inthecaseofachild/adolescentpreviouslydiagnosedwithproblem-levelinattentionorhy-peractivity,repeatingthediagnosticevaluationmightresultinadiagnosisofADHD,whichwouldallowforin-creasedschoolsupportsandtheinclu-sionofmedicationinthetreatmentTreatmentfailurecouldalsosignalpooradherencetothetreatmentplan.Increasedmonitoringandeducation,especiallybyincludingthepatientearlyinhisorhertreatment,mightin-creasetreatmentadherence.Itishelp-fultotrytoidentifytheissuesthatre-strictadherence. Yes chronic care management at least 2x/year for ADHD issues Intheearlystagesoftreatment,afterasuccessfultitrationperiod,thefre-quencyoffollow-upvisitswilldependonadherence,coexistingconditions,andpersistenceofsymptoms.Asnotedpreviously,ageneralguideforvisitstotheprimarycareclinicianisforthesevisitstooccurinitiallyonamonthlybasis,thenevery3monthsintherstyearoftreatment.Morefre-quentvisitsmightbenecessaryifco-morbidconditionsarepresent.Visitsshouldthenbeheldatleasttwiceeachyearwithadditionaltelephonemoni-toringatthetimeofmedication-rellrequests.Ongoingcommunicationwiththeschoolregardingmedicationandservicesisalsoneeded.Itshouldbenotedthatatthispoint,thereislittleevidencetoestablishtheoptimal,yetpractical,follow-upregi-men.Itislikelythattheregimenwillneedtobetailoredtotheindividualchild/adolescentandfamilyneedsonthebasisofclinicaljudgment.PREPARINGTHEPRACTICESpecicofcepracticeproceduresthatfacilitatetheoptimalandefcientdiagnosisandtreatmentprocessarecriticalforsuccessfulmanagementofchildren/adolescentswithADHD.MoredetailcanalsobefoundinthereportoftheAAPTaskForceonMentalHealth.Theofceprocesscaninclude:developingapacketofADHDques-tionnairesandratingscalesforpar-entsandteacherstocompletebe-foreascheduledvisit;allottingadequatetimeforADHD-relatedvisits;determiningappropriatebilling,documentation,andmonitoringofinsurancepaymentstoensurethattheyadequatelycovertheservicesimplementingmethodstotrackandSupplementalAppendixPEDIATRICSVolume,Number, follow-uppatients(refertomedicalhomeproceduresformoredetail);askingquestionsduringallclinicalencountersandplacingbrochuresandpostersintheofcetoalertpar-entsandchildren/adolescentsthatbehaviorandschoolproblemsandADHDareappropriateissuestodis-cusswiththeclinician;developinganofcesystemformonitoringandtitratingmedication(afollow-upsystemshouldincludethecliniciansassessmentoffamilyorganization,telephoneaccess,andparent-teachercommunicationef-fectiveness);andcollaboratingwithschoolsandotherinvolvedcommunityprovidersandresourcesthatcanenhancetheprocessforADHDdiagnosisandmanagement,whichcanbeachievedonacase-by-casebasisthroughcoordinationofthediagno-sisandtreatmentplanamongschoolstaff,theclinician,parents,andotherinvolvedprofessionals(notethatthisless-systematicap-proachcarriessignicantchal-lenges,includingensuringconsis-tentcareforallchildren/adolescentswithADHD).Acommunity-levelsystemthatreectsconsensusamongdistrictschoolstaffandlocalprimarycarecliniciansforkeyelementsofdiagnosis,interven-tions,andongoingcommunicationcanhelptoensureconsistent,well-coordinated,andcost-effectivecare.Acommunity-basedsystemwithschoolsrelievestheindividualprimarycareclinicianfromnegotiatingwitheachschoolaboutcareandcommunicationregardingeachpatient.Ofcesthathaveincorporatedmedicalhomeprin-ciplesareidealforestablishingthiskindofcommunity-levelsystem.Thekeyelementsforacommunity-basedcollaborativesystemincludeconsen-suson:aclearandorganizedprocessbywhichanevaluationcanbeinitiatedwhenconcernsareidentiedbyei-therparentsorschoolpersonnel;apacketofinformationcompletedbyparentsandateacherabouteachchild/adolescentreferredtotheprimarycareclinician;acontactpersonatthepracticetoreceiveinformationfromparentsandteachersatthetimeofevalua-tionandduringfollow-up;anassessmentprocesstoinvesti-gatecoexistingconditions;adirectoryofevidence-basedinter-ventionsavailableintheanongoingprocessforfollow-u
18 pvisits,telephonecalls,teacherre-ports,a
pvisits,telephonecalls,teacherre-ports,andmedicationrells;availabilityofformsforcollectingandexchanginginformation;andaplanforkeepingschoolstaffandprimarycarecliniciansup-to-dateontheprocess.Theclinicianmightfacechallengestodevelopingsuchacollaborativepro-cess.Asexamples,theprimarycareprovidermightbecaringforchildren/adolescentsfrommorethan1schoolsystem;aschoolsystemmightbequitelargeandnoteasilyaccessed;schoolsmighthavelimitedstaffandresourcestocompleteassessments;oritmightbedifcultforthephysicianandteacherorotherschoolpersonneltocommunicatebytelephonebecausetheirschedulesdiffer.Therearework-ablestrategiesforaddressingeachofthesechallenges.Inthecaseofmultipleorlargeschoolsystemsinacommunity,theprimarycareclinicianmightwanttobeginwith1schoolpsychologistorprincipal,orseveralpracticescaninitiatecontactcollectivelywithacommunityschoolsystem.Agreementamongtheclini-ciansonthecomponentsofagoodevaluationprocessfacilitatescooper-ationandcommunicationwiththeschooltowardcommongoals.Forex-ample,agreementonthebehaviorrat-ingscalesusedcanfacilitatecomple-tionbyschoolpersonnel.StandardcommunicationformsthatmonitorprogressandspecicinterventionscanbefaxedbetweentheschoolandthepediatricofcetoshareCollaborativesystemsalsoextendtootherproviderswhomaycomanagecarewiththeprimarycareclinician.Providersmayincludeamentalhealthprofessionalwhoseesthechild/ado-lescentforpsychosocialinterventionsoraspecialistwhoaddressesdifcultcases,suchasadevelopmental-behavioralpediatrician,childpsychia-trist,childneurologist,neurodevelop-mentaldisabilityphysician,orpsychologist.Agreed-onprocessesforroutinecommunicationcanalsobeusedintheserelationships.TheAAPTaskForceonMentalHealthprovidesafulldiscussionofcollaborativerela-tionshipswithmentalhealthprofes-sionals,includingcolocationandinte-gratedmodels,initsChapterActionandPedialinkModule.Itisimportanttonotethatgoodcarefrequentlyrequiresactivitiesthatcur-rentlyarenotreimbursed.Theseactiv-itiesincludecontactswithteachersandmentalhealthconsultantsandnon face-to-facecontactwithparentsandpatients.Itwouldbehelpfulforcli-nicianstodocumentthenonreim-bursedeffortsandforthenationalAAP,statechapters,andclinicianstocontinuetotrytomakethird-partypay-ersunderstandtheneedfortheseef-fortsandprovidecompensationforthisappropriatecare.COMPLEMENTARYANDUNPROVENFamiliesofchildren/adolescentswithADHDincreasinglyaskaboutcomple-FROMTHEAMERICANACADEMYOFPEDIATRICS mentaryandalternativetherapiesforADHD.Suchtherapiesmightincludelargedosesofvitamins,essentialfattyacids,andotherdietaryalterations;chelation;andelectroencephalo-graphic(EEG)biofeedback.Todate,thereisinsufcientevidencetodeter-minewhetherthesetherapiesleadtochangesincoresymptomsofADHDorfunction,andformanyofthem,thereislimitedinformationabouttheirsafety.Forthesereasons,thesethera-piescannotberecommended.Sometherapies,chelation,andmegavita-minshavebeenproventocausesomeadverseeffectsandarePhysicianscanplayaconstructiveroleinhelpingfamiliesmakethoughtfultreatmentchoicesbyreviewingthestatedgoalsoreffectsclaimedforagiventreatment;thestateofevidencetosupportordiscourageuseofthetreatment;andknownorpotentialad-verseeffects.Physiciansshoulden-couragefamiliesthatwishtopursuethesetreatmentstotry1interventionatatime,choosetargetgoalstheywilluse,monitorcoresymptomstomea-sureefcacy,andchooseatimeframeinwhichtheyanticipatethechangestooccur.Familiesshouldalsobestronglyencouragedtocontinuetousethemoreevidence-basedinterventionsatthesametimethattheyareexploringcomplementaryandalternativeCliniciansshouldrespectfamiliesin-terestsandpreferenceswhiletheyad-dressandanswerquestionsaboutcomplementaryandunproventhera-piestopreserveandenhancetheclini-cian/familyrelationship.Inaddition,primarycarecliniciansshouldknowaboutadditionaltherapiesthatfami-liesmightbeadministeringtoade-quatelymonitorfordruginteractions.Parentsandchildren/adolescentswhodonotfeelthattheirchoicesinhealthcarearerespectedbytheirprimarycareclinicianmightbelesslikelytocommunicateaboutcomplementaryoralternativetherapies.Furtherinformationaboutcomple-mentaryandothertherapiespro-mot
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