PPT-Developing a Vaccine against Pneumonia,

T he Captain of Death Osler History 1881 Louis P asteur discovers the pneumococcus bacterium 1886 Gold mining begins in South Africa 1895 Pneumococcus identified as the cause of epidemic pneumonia that kills 35 of miners who are infected. It is . not possible . to distinguish between bacterial and viral pneumonia on clinical grounds alone!. Suggestive of bacteria:. Rapid . onset (. tachypnea. , cough, retractions). Likely to appear very sick. Daniel Urschel, MD, Charles Pace, MD, Sherman Alter, MD. Department of Pediatrics, . Boonshoft. School of Medicine, Wright State University, The Children’s Medical Center of Dayton. Clin Infect Dis 2011; 53 (7): 617-630. bacterial pneumonia. . Lessons learned—and yet to be learned. William Hausdorff, PhD. Vaccine Development Leader, Pneumococcal Vaccines. GlaxoSmithKline . Biologicals, . Wavre. , Belgium. Pneumonia is the major manifestation of . Sally Crane . Respiratory Nurse Consultant . The Facts 2015/16 . There are . approx. 3.2 . million people . with Chronic Obstructive Pulmonary Disease. (. 1:10 people over 40). . Approx. 8 million people including children have asthma and use inhalers.. Bonnie L. Hinds. June 2012. June 2012. “An ounce of PREVENTION. i. s worth a pound of. c. ure.”. Henry de Bracton. 1210-1268. Average life expectancy. in 1200s –. 43. 2. Vaccines are considered to be . Healthy People 2020 goal:. Increase immunization rates and reduce preventable infectious diseases.. 1. 2. Why We immunize. Health promotion: prevent a disease if it is preventable.. Morbidity vs Mortality. (CAP) . Objectives. Discuss the epidemiology and pathophysiology of pneumonia and CAP. Explain the different classifications of pneumonia. Recognize clinical presentations associated with CAP. Discuss the diagnosis and treatment of CAP. By:. Lecturer Dr. . Thanaa. . Rasheed. Outline. Haemophilus. . influenzae. ,. . Bordetella. . pertussis. ,. . Legionella. . pneumophila. .. Important Properties. Diseases and Pathogenesis, . Laboratory Diagnosis. 2. J. Matthew Velkey, PhD. Department of Cell Biology. Duke University School of Medicine. Andrew Alspaugh, MD. Department of Internal Medicine. Infectious Disease Division. Duke University School of Medicine. 1. J. Matthew Velkey, PhD. Department of Cell Biology. Duke University School of Medicine. Andrew Alspaugh, MD. Department of Medicine. Infectious Disease Division. Duke University School of Medicine. Advancing technologies to improve vaccine performance and delivery.. Darin Zehrung. Developing Countries Vaccine . Manufacturers’ Network Meeting. Hyderabad, India. 16 September, 2010. Presentation Overview. Print and display the pages as is or customize them with additional information or your facility’s logo (space allotted in the top right corner of each slide).. The content can be used on bulletin boards, in staff common areas, visitor reception areas, at staff or family council meetings and in mailings.. Pneumonia is an acute infection of lung parenchyma characterized by (accumulation of secretions and inflammatory cells in alveoli). . Clinical classification. Community-acquired . pneumonia (CAP):. Joshi . MD (. kaumarbhritya. ). Assistant professor . HAMCH. . Definition-. Pneumonia is defined as an inflammatory . condition . . involving lung parenchyma usually due to microorganism..