PPT-HUMAN HERPES VIRUSES -1

Dr D Kalita Associate professor Department of Microbiology AIIMS Rishikesh Date of Class 2642017 4PM to 5PM LT4 DNA Viruses Members causing disease in Humans Herpesviridae Herpes simplex 1amp2 . DNA Enveloped . Viruses. I. Objectives. In this lecture you will learn about properties, pathogenesis, clinical picture and diagnosis of: . Herpesviruses. . (HHVs 1 to 8). Poxviruses. Smallpox Virus. copyright cmassengale. 2. Are Viruses Living or Non-living?. Viruses are both and neither. They have . some properties of life but not others. For example, viruses can be killed, even crystallized like table salt. CLS 212: Medical Microbiology. History. Through the 1800s, many scientists discovered that something smaller than bacteria could cause disease and they called it . virion. (. Latin word- poison. ).. Chapter 18. Are Viruses Alive?. As a group discuss for 1 minute. Be able to defend your answer for the class!. Are . VIRUSES. alive?. Growth and Development. Reproduce. Change Over Time. Obtain and Use Energy. Antiviral agents . Viruses have one major characteristic in common: they are obligate intracellular parasites. . Virology; the study of viruses. Viruses are UNABLE to grow and reproduce outside of a living cell. No virus is able to produce its own energy (ATP) to drive macromolecular synthesis.. Pages 476 - 495. A Rhinovirus . The Flu. What is a Virus??. Non-living particles that can’t reproduce. nucleic . acids . (DNA or RNA) . enclosed . in a protein coat . Smaller than the smallest bacterium . (first animals). - EUKARYOTIC, UNICELLULAR, HETEROTROPHS. - PROTOZOA ARE CLASSIFIED BY THEIR METHOD OF MOTILITY. 1. Phylum . Sarcodina. - use pseudopods for motility. - . Naegleria. . fowleri. HHV. HERPES VIRUSES:. Enveloped ,dsDNA viruses. Similar morphologically but differ clinically and biologically. Three groups:. 1-ALPHA-HRPES VIRUSES. (. HSV. -1,. HSV-2,. AND . VZV. ). . 2-. BETA-HERPESVIRUSES. K berry. . Affect the skin or mucous membranes of face or oral cavity.. Oral tissues are a frequent site for primary infections and also when there is reactivation of latent viruses.. Most do not require specific treatment and are self limiting in otherwise healthy individuals.. By . Dr.Hesnaa. . Saeed. Al-. Mossawi. DNA VIRUS. RNA VIRUS. Transmission of viral infection. Viruses are transmitted via horizontal (common route of transmission: person to person), and vertical (mother-to-child transmission) routes or . Karposi's. sarcoma herpesvirus (HHV-8). . HUMAN HERPESVIRUSES. Virion. Structure . All herpesvirus . virions. have four structural elements. . Core. . The core consists of a single linear molecule of dsDNA in the form of a torus. . (. Persistent Human Viruses. ). 1- Large family of viruses 150–200 nm in diameter. . 2-The . nucleocapsid. is 100 nm in diameter, with . cubic symmetry . and 162 . capsomeres. , surrounded by a lipid-containing envelope. . detected by by 46]. The classification of herpes viruses according to their morphology shows a structural similarity for all herpes viruses, which are found in more than 50 different animal species. T History. Through the 1800s, many scientists discovered that something smaller than bacteria could cause disease and they called it . virion. (. Latin word- poison. ).. In the 1930s, after the invention of electron microscopes, viruses finally could be seen..