PPT-Section C Pathophysiology of diabetic nephropathy & risk factors for the development

Objectives and background for this learning resource Introduction This learning resource has been developed as part of a medical education initiative supported by Janssen The content of this slide kit has been developed by an advisory board of renal physicians GPs and specialist nurses The panel of experts . Patel University. Efficacy of Urinary N-Acetyl β- D- Glucosaminidase in Detecting Renal Tubular Damage: A Early Consequence in Type 2 Diabetes Mellitus leading to Diabetic Nephropathy. Kiran. . Sierra Nevada Nephrology Consultants. Outline. Define the illness. Recent state of Affairs. Pathology. Risk factors. Medication. Treatments. Diabetic nephropathy is a clinical . syndrome. Persistent . Learning Objectives. Utilize appropriate screening tools, such as GFR and ACR, in order to diagnose and monitor CKD patients.. Classify CKD, based on GFR and albuminuria categories, in order to guide appropriate treatment. . Data Source: National Health and Nutrition Examination Survey (NHANES), 1988–1994, 1999-2004 & 2007–2012 participants aged 20 & older. Whisker lines indicate 95% confidence intervals. Abbreviations: CKD, chronic kidney disease. This graphic also appears as Figure 1.2. Chapter 1: CKD in the General Population 2017 Annual Data Report Volume 1: Chronic Kidney Disease 2 Table A Kidney Disease Outcomes and Quality Improvement (KDOQI) CKD Staging Guidelines CKD Stage Description kidney disease . in . diabetes :. In . either . type 1 or . type 2 diabetes : . 25 – 40. % . → diabetic . nephropathy in a 25 . y. Diabetes . → leading cause for ESRD. diabetic . nephropathy :. Hyperkalemia, Metabolic Acidosis, Malnutrition, Depression & Acute Kidney Injury. Andrew . Narva. , MD, FASN & . Amy Barton . Pai. , PharmD, MHI, FASN, FCCP, FNKF. Andrew . Narva. , MD, FASN. In CKD and HD patients dysfunction of . immu. ne . sy. stem . a. lterations. . belonge. to . . involv. ing. . i. nnate. and . a. daptive. . i. mmunity. in T and B lymphocytes (. Reduced . T regulatory cells and memory cells and increased innate cells). . Pathology Of Gouty Nephropathy. Uric acid crystals and . urates. are deposited in the kidney.. This leads to irritation and acute . inflammation,more. time, more deposition.. This deposits act as . ABSTRACTGreat advances have been made in the pathophysiologic and therapeutic areas of membranous nephropathy in the last years. The description of autoantibodies directed against phospholipase A2 rec 5 5 DOI: 10.7860/JCDR/2018/36574.12203 Original Article Miscellaneous Postgraduate Education Letter to Editor Short Communication Images in Medicine Experimental Research Clinician’s corner Revie P. Risk factors in the progression of dia-betic nephropathies. Ugeskr Laeger 2000; 162:P, NARVINGNatural course of kidney function in type 2 diabet-ic patients with diabetic nephropathy. Diabet Med199 P. Belton, M. Carmody, J. Doino:hue and W. F. O'Dwyer of Nephrology, Jervis Street Hospital, Dublin 1. I gA nephropathy is a newly described glomerulonephritis. It is a relatively common nephritis o .. สุดารัตน์ . ศุภ. กิจเจริญ. หน่วยงานวิสัญญี โรงพยาบาลกำแพงเพชร. Etiology of CKD. In UK , most common causes are;.