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Preclinical and Early Clinical: ADME II and Pharmacodynamic Preclinical and Early Clinical: ADME II and Pharmacodynamic

Preclinical and Early Clinical: ADME II and Pharmacodynamic - PowerPoint Presentation

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Uploaded On 2016-11-05

Preclinical and Early Clinical: ADME II and Pharmacodynamic - PPT Presentation

Lecture 42 1 Outline Allometry Microdosing Predicting Clearance Absorption Distribution and Metabolism Whole Body Physiological Models Predicting Pharmacodynamics Virtual Patient Populations ID: 484877

inhibition drug cyp3a4 metabolic drug inhibition metabolic cyp3a4 clint metabolism microsomes cyp3a5 vitro rate enzyme stability vivo metabolite human

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