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A randomized trial of assessment interventions to reduce drug use and HIV/STI sexual risk A randomized trial of assessment interventions to reduce drug use and HIV/STI sexual risk

A randomized trial of assessment interventions to reduce drug use and HIV/STI sexual risk - PowerPoint Presentation

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A randomized trial of assessment interventions to reduce drug use and HIV/STI sexual risk - PPT Presentation

A randomized trial of assessment interventions to reduce drug use and HIVSTI sexual risk among young adults who use drugs in the club scene Steven P Kurtz Mance E Buttram Maria E Pagano and Hilary L Surratt ID: 762405

drug results club acasi results drug acasi club south beach study symptoms substance control capi reduce interventions data national

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A randomized trial of assessment interventions to reduce drug use and HIV/STI sexual risk among young adults who use drugs in the club scene Steven P. Kurtz, Mance E. Buttram, Maria E. Pagano, and Hilary L. Surratt Lisbon Addictions - 24 - 26 Oct. 2017

This research was supported by grant number DA0196048 from the National Institute on Drug Abuse. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute on Drug Abuse or the National Institutes of Health. There are no conflicts to report. Support

Miami is an international center of nightclub culture“Every night is like New Year’s Eve on South Beach, and drugs and sex are all part of it.”

Illicit “club drugs” include: EcstasyCocaineMethamphetamineLSDGHB“Designer” stimulants and hallucinogens Club Drugs

Background Extensive polydrug use among nightclub attendees Pervasive resistance to participation in formal interventions Efficacious interventions to reduce drug use and related consequences are not apparent.

The South Beach study RCT of behavioral interventions to reduce substance use and HIV transmission risk among young adults.

The South Beach study Study arms: 1) interviewer-administered (CAPI) and 2) self-administered (ACASI) comprehensive health and social risk assessments and 3) waitlist control

OUTCOME MEASURES Primary Outcomes (past 90 days):Club drug use frequencyRisky vaginal/anal sex frequencyMeasured at baseline and 3-, 6- and 12-months post intervention.

HypothesisParticipants randomized to the CAPI and ACASI intervention conditions will reduce their substance use and related behaviors more than those assigned to waitlist control.

The South Beach study Eligibility criteria: Ages 18-39 Past 90 day behaviors Heterosexual sex Used “club drugs” at least 3 times Misused a scheduled Rx drug Attends large EDM clubs

The South Beach study Respondent Driven Sampling N=750 Enrollment 2011-2014

MEASURESSubstance use abstinence frequency Substance dependence symptoms: DSM-IV items, including withdrawal symptoms and tolerance (range 1-7). Mental distress symptoms: DSM-IV items assessing past year anxiety, depression and somaticism (range 1-25).

Analytical approachIntent to treat basis Effect size estimates (Cohen’s d)Log-transformed measures

Results a 57 controls missing data (did not complete 12-month assessment)

Results a 57 controls missing data (did not complete 12-month assessment); b One ACASI participant missing data.

Results

results

results

results

LIMITATIONS Data are self reported Eligibility criteria limit generalizability Diagnostics not clinician-administered

Hypothesis partially confirmed – CAPI was superior to control.Substance dependence and mental distress symptoms below clinically significant levels Contrary to the hypothesis – ACASI showed lower efficacy compared to control Conclusions

Interpersonal interaction appears beneficial Demonstrates efficacy of single session intervention Acceptable to target populationNo difference between CAPI – ACASI on ‘sensitive’ measures Conclusions

Thank youSteven P. Kurtz and Mance E. Buttram arsh.nova.edu