PDF-(BOOK)-Biodefense in the Age of Synthetic Biology

Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature Synthetic biology which collectively refers to concepts approaches and tools that enable the modification or creation of biological organisms is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution Although the contributions synthetic biology can make in these and other areas hold great promise it is also possible to imagine malicious uses that could threaten US citizens and military personnel Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology assesses the levels of concern warranted for such advances and identifies options that could help mitigate those concerns. 1 SYNBIO 5about Do-It-Yourself Biology 2 Table of ContentsIntroductionMany DIYers Work in Multiple SpacesDIYers work anonymously and solitarilyDIYers are capable of unleashing a deadly epidemicDIYers April 18, 2012. Is the Precautionary Principle Needed?. Woodrow Wilson International Center for Scholars. Eric Hoffman. Food & Technology Policy Campaigner. Friends of the Earth U.S.. Background. Synthetic Biology- Precautionary Principle. 1. “. When an activity raises threats of harm to human health or the environment, precautionary measures should be taken even if some cause and effect relationships are not fully established scientifically. In this context the proponent of an activity, rather than the public, should bear the burden of proof. The process of applying the Precautionary Principle must be open, informed and democratic and must include potentially affected parties. It must also involve an examination of the full range of alternatives, including no action. Domitilla. Del . Vecchio. Department of Mechanical Engineering. MIT. May 24. th. . 2011, . Sontagfest. 1. Molecular Systems Biology . and Eduardo. 2. CDC 2005 Tutorial Session an EJC 2005: Molecular Systems Biology and Control. Introduction to Building with Biology:. About the project. What is synthetic biology?. Conversations with visitors. Our Building with Biology Event . Hands-on activities. Logistics. Presentation Overview. Case Studies. Herbert M Sauro. www.sys-bio.org. www.sbml.org. www.sbolstandards.org. blog.analogmachine.org. Dept. of Bioengineering. University of Washington, Seattle, WA. hsauro@u.washinton.edu. 1. Arti. . Rai. and James Boyle. Presented by Pei-Ann Lin. May 11, 2011. Synthetic Biology and Intellectual Property Law. What is the best method for creating “openness” and thus, greater innovation?. . Biology. , London. 1. Jean A. Boutin. . (Institut de . Recherches. Servier, France). Use of synthetic proteins and future trends: . the example of calstabin. 20160818. 2016 . Synthetic. . Biology. Synthetic Biology:. . A Brief Survey. http://. news.mit.edu. /topic/synthetic-biology. What is Synthetic Biology?. Synthetic biology is programming biological matter.. Schwille. , P. Science 333, 1252–4 (2011).. & The Central Dogma . IGEM Presentation 1. 7. th. July 09. Dineka Khurmi. James magA Field. Synthetic Biology. . Last century & SB potential. . US leads with:. - $16m funding of SynBERC (UC Berkeley). What is synthetic biology?. The synthetic yeast project. The Scramble system. Network analysis to understand cell dynamics. Synthetic Biology?. What is. Robert H. Newman. North Carolina A&T State University. Domitilla. Del . Vecchio. Department of Mechanical Engineering. MIT. May 24. th. . 2011, . Sontagfest. 1. Molecular Systems Biology . and Eduardo. 2. CDC 2005 Tutorial Session an EJC 2005: Molecular Systems Biology and Control. Briefing webinar. January 2021. The Synthetic Biology Process. Process. Information. . Pre-sessional document (CBD/SBSTTA/24/4 ) + 4 information documents. Submissions. Online Forum. AHTEG. Other requests. modified. human proteome . Human proteins exhibit highly complex patterns of posttranslational modifications (PTMs) that govern their structure and function. These modifications are omnipresent in human health and disease. However, technical barriers have limited the study of PTMs which keeps the knowledge of our proteome in a persistent state of “physiological dark matter”. .