PPT-DISEASES OF MUSCLE myopathy

is a muscle disease unrelated to any disorder of innervation or neuromuscular junction These conditions have widely varying etiologies including congenital or inherited idiopathic infectious metabolic inflammatory endocrine and druginduced or . Cataracts . clouding of the normally clear lens of your eye. looking through a frosty or fogged-up . window. difficult to read, drive a car (especially at night) or see the expression on a friend's face. . Rachel Garvin, MD. Assistant Professor, . Neurocritical. Care. Department of Neurosurgery. Objectives. Describe critical care myopathy and neuropathy, causes, diagnosis and management. Describe CNS infections, diagnosis and management. A Biological Love Story Gone Wrong. Corey Cannon, MS3. Russell Romano-Kelly, MS3. Corbin Shawn, MS3. Presentation given by 3rd year medical students. at Pediatric Neurology Grand Rounds,. Valentines Day (2/14/2014). Who are our Neuromuscular Great . Great. grandfathers ?. Shy, Engel, Brooke, & the NIH connection. Richard J. Barohn, M.D.. Gertrude and Dewey Ziegler Professor of Neurology. The University of Kansas Medical Center. Robert Murphy, MD. Clinical Neurophysiology Fellow. Disclosures. none. Outline. Definitions of Idiopathic Inflammatory Myopathies. Therapeuti. c Options. Polymyositis. Dermatomyositis. Necrotizing Myopathy. James J. Lehman, DC, MBA, FACO. Associate Professor of Clinical Sciences. School of Chiropractic. Director. Community Health Clinical Education. University of Bridgeport. Learning Objectives. . Organize a clinical thought process while performing a neuromusculoskeletal evaluation of a patient with statin myopathy and piriformis syndrome.. Contractile. Made of contractile proteins. Cells are called fibers. Skeletal Muscle. 40% of body weight. Under voluntary control; attached to skeleton. Striated, or banded, appear. ance. Cells have multiple nuclei. Muscles and Muscle Fiber. Structure.     . Muscles are composed of many fibers that are arranged in bundles called FASCICLES. Individual muscles are separated by FASCIA, which also forms tendons. Deltoid. The muscle on the front of your upper arm. Biceps. Your chest muscles. Pectoralis. Major. Your stomach muscles (Abs). Rectus . Abdominus. The muscles on the side of your “core” – or “next to your abs”. A. Traditional Bergstrom Needle B. UCH Needle (modified Bergstrom) Bergstrom and UCH needles: Dixons, a surgical instrument manufacturer in the http://www.dixons-uk.com/index.asp Bergstrom needles on Safetyfactortime (ms)membrane potential (mV)40200-20-40-60-80-90020406080100120140Safety factortime (ms)membrane potential (mV)NormalMyasthenia gravisNo contractionThe decrease in the number of availa ProteinShift slow-twitch �bers towards fast-twitch MYH1, MYH2, Shift slow-twitch �bers towards fast-twitch Calcium-transporting ATPaseIncrease Ca storage in SRIncrease ATP consum 1 South African Rheumatism & Arthritis Association SARAA Patient Education Resources; by Dr Mpoti Seboka updated May 2020 2 Gottron’s sign or Gottron’s papules – Gottron’s sign is a 昀 Skeletal Muscle Structure . Muscle = group of fascicles. Muscle fibers extend length of muscle from tendon to tendon. Components of a muscle fiber. Motor units. Motor unit: Composed of one motor neuron and all the muscle fibers that it innervates.