PPT-Novel genetic subgroups inform on shared pathobiology within adult and pediatric Burkitt

Nicole Thomas Morin Lab SFU Burnaby BC Canada Burkitt lymphoma disproportionally affects children 2 Adult OS Pediatric OS Swerdlow et al 2016 Liu et al 2019 WGS amp RNA Sequencing. IRIA- 1192. Case Discussion. A 46 year old male with complaints of. . -. Dysphagia. x 2 weeks. . -. Epigastric. Pain x 2 weeks. . -Vomiting x 40 hours. An upper gastrointestinal endoscopy was done which revealed a gastro-duodenal junction growth invading the . Common (West), low-grade B-cell lymphoma. Affects elderly. Arises from germinal center B-cell. Lymphoma cells have specific translocation t(14:18), in which Bcl2 gene on chr18 fuses with . IgH. gene on chr14, causing . Virginia C. . Broudy. , MD. September 25, 2014. Presentation prepared by: . Presenter. Last Updated: . Date. AIDS-Defining Malignancies. Kaposi sarcoma . NHL – now has a higher incidence than Kaposi Sarcoma in the US. and their . precursor . cells. .  The name often refers to just the . cancerous. . ones . rather than all such . tumors. .. Many lymphomas are known to be due to specific genetic mutations.. 3. rd. a closer look . SEER HEMATOPOIETIC DATABASE. Understanding the disease. AMBIGUOUS TERMS. Choosing . the right . Histology & TOPO CODE . Navigation of the Hematopoietic and Lymphoid Neoplasm Database . Therapeutic Targets in CLL. Venetoclax in Patients With 17p Deletion. Venetoclax in Patients With 17p Deletion (cont). Bendamustine Plus Obinutuzumab. Ibrutinib Plus Ublituximab. Updates in Lymphoma From Recent Congresses. Mariko Yabe, MD. PhD, Guilin Tang, MD. PhD, . Ken . H. Young, MD. PhD, Sa A. Wang, MD. .. Department of Hematopathology, . UT . MD Anderson Cancer Center, . Houston. , Texas, USA. Case: 57 year-old Caucasian . Prof Ivy A E . Ekem. 16. th. September 2016. Blood. en.wikipedia.org / M. . Komorniczak. . Accessed 08.09.16. Development of blood cells. en.wikipedia.org. Site of blood formation. www.healthline.com>Ref Library. Sima Jeha, MD nhl. Presenting by . F.Malek. M.D. Assistant Professor Ped Hematologist & Oncologist . Mofid. Children’s Hospital. Introduction. The non-Hodgkin lymphomas (NHLs) occurring in children and adolescents and young adults (AYA) are characterized by various age-related differences in tumor biology and survival. . MODERATOR : DR. GANAPULE . Definition . Lymphomas are malignant . tumours. of lymphoid tissue which give rise to solid tissue masses.. Heterogenous. group of disorders.. HODGKINS LYMPHOMA. NON-HODGKINS. This is a controlled document and therefore must not be changed or photocopied L.13 High dose METHOTREXATE (high grade NHL CNS prophylaxis) Authorised by Lymphoma lead Dr. Graham Collins Date: M Helpline: 800 500 9976 | helpline@lymphoma.org Understanding LymphomaDiffuse Large B-Cell Lymphoma: Relapsed/Refractory Diffuse large B-cell lymphoma (DLBCL) is the most common form of non-Hodgkin l Ann Marie Szymanski, MD. Johns Hopkins All Children’s Hospital. FAAP, FACR. Agenda. Adult and Pediatric Rheumatology Workforce. Juvenile Idiopathic Arthritis. Childhood-Onset Systemic Lupus Erythematosus.