RISK ASSESSMENT THROUGH PASSIVE SMOKING GROUP MEMBERS PRAGYA AGRAWAL2013AST2050 PRIYA 2013CEW2212 SANDEEP SARNA 2013CEW2214 Assistant Professor Department of Civil Engineering ID: 218691
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Slide1
INHALATION
RISK ASSESSMENT THROUGH PASSIVE SMOKING
GROUP MEMBERS
: -
PRAGYA AGRAWAL(2013AST2050),
PRIYA (2013CEW2212),
SANDEEP SARNA (2013CEW2214
)
Assistant Professor
Department of Civil Engineering
Indian Institute of Technology-Delhi, New Delhi-110016 (INDIA)
Email:
arunku@civil.iitd.ac.in
Contact No.:
011-26591166Slide2
Data Collection:142 Persons are surveyedThey are divided according to Brand of Cigarette and Age.Nicotine content of each Brand and Bidis was found and Risk Analysis was doneGroups
Most Exposed : 6 % Nicotine IntakeLeast Exposed : 1 % Nicotine Intake
Group A
: Children under 15
yrs.
Group B
: Pregnant women &Group C : Adults
Sr. No.EventSeverityProbability1Children Most Exposed to ETSCatastrophic Frequent2Children Averagely Exposed to ETS MarginalProbable3Pergenant Lady Most Exposed to ETSCriticalFrequent4Pergenant Lady Averagely Exposed to ETSMarginalProbable5Adults Most Exposed to ETSCriticalFrequent6Adults Averagely Exposed to ETSNegligibleProbable
Probability and Severity TableSlide3
Inhalation of ETS (Nicotine) by
subject at public places
Subject passing
nearby and inhales cigarette smoke
Presence of ETS (Nicotine) in
the
public
environmentPresence of Nicotine in Cigarette of SmokerSmoker smokes At Public place Inhalation of ETS (Nicotine) by subject at office premiseSubject passing nearby and inhales cigarette smokePresence of ETS (Nicotine) in the office premisePresence of Nicotine in Cigarette of SmokerSmoker smokes Inside office premiseInhalation of ETS (Nicotine) by subject at HomeSubject passing nearby and inhales cigarette smokePresence of ETS (Nicotine) in HomePresence of Nicotine in Cigarette of SmokerSmoker smokes At Home
Non-Carcinogen effect of ETS (Nicotine) to a passive smoker
and
and
and
and
and
and
or
Fault TreeSlide4
Parameter
Distribution of Parameter
Base Hazard Quotient (low value, high value)
Children
Pregnant Lady
Adults
Most Exposed
Avg. Exposed Most Exposed Avg. Exposed Most ExposedAvg. ExposedCigerrette Intake (no. of Cig./day)8 (3, 17)85.84 (32.19,182.41)3.57 (1.34, 7.6)28.6 (10.73,60.8)1.2(0.44, 2.53)15.32 (5.74,32.5)0.64(0.24, 1.35)Nicotine Content (mg/cigerette) (In most exposed group)0.6438 (0.5973, 0.9402)85.84(79.64, 125.36)28.6 (26.54, 41.7)15.32 (14.22, 22.38)
Nicotine Content (mg/cigerette) (In avg. exposed group)
0.1073 (0.0995, 0.1567)
3.57 (3.31, 5.22)
1.2 (1.1,1.74)
0.64 (0.59, 0.93)
Sensitivity Index (Cig. Intake)
85.84
3.57
28.6
1.2
15.32
0.64
Sensitivity Index (Nicotine Content))
85.84
3.57
28.6
1.2
15.32
0.64
Risk Characterization: Hazard Quotient
Assumptions Involved:
Exposure Duration for Most Exposed Group = 4 Hr per Day
Exposure Duration for Avg. Exposed Group
=
1 Hr per Day
Parameter
Children
Pergenant Lady
Adults
Body Weight (Kg)
20
50
70
RfD
of Nicotine (mg/(
Kg.day
)
0.0005
0.0006
0.0008Slide5
CONCLUSIONS AND RESULTS:-
Avoided
zone:
Chidren
, Pregnant Lady and Adults (most exposed)
Accepted
by Waiver : Chidren, Pregnant Lady (average exposed) Routingly Accepted zone : Adults (average exposed)Effect on Children:-Most Exposed85.84High Risk (Must be Avoided)Average Exposed3.57Low Risk Effect on Pregnant LadyMost Exposed28.6High Risk (Must be Avoided)Average Exposed1.2Low Risk Effect on Pregnant LadyMost Exposed15.32High Risk (Must be Avoided)Average Exposed0.64Acceptable Risk