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Requirements for and Challenges associated with BSL4 laboratories Requirements for and Challenges associated with BSL4 laboratories

Requirements for and Challenges associated with BSL4 laboratories - PowerPoint Presentation

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Requirements for and Challenges associated with BSL4 laboratories - PPT Presentation

Dr Greg Smith Microbiological Security Manager Australian Animal Health Laboratory Geelong Victoria How many are needed Australia population of 225 million 4x BSL4 Laboratories 1 x National Animal High Containment Lab AAHL ID: 920668

greg smith 2011 istanbul smith greg istanbul 2011 july staff lab bsl3 bsl4 amp state csiro training animal health

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Presentation Transcript

Slide1

Requirements for and Challenges associated with BSL4 laboratories

Dr Greg Smith

Microbiological Security Manager

Australian Animal Health Laboratory

Geelong, Victoria

Slide2

How many are needed?

Australia – population of 22.5 million

4x BSL4 Laboratories

1 x National Animal High Containment Lab (AAHL)3x State Public Health PC4 labs (Brisbane, Sydney and Melbourne)Expansion of AAHL new PC4 lab 320 m2

CSIRO . Greg Smith Istanbul July 2011

Slide3

Australian Animal Health Lab

Opened in 1985

26 years old

$200M to build

Replace $650-700 35 hectares Building 2 Ha6 Floors 65,000 m

2 15,000m2 ‘lab’LabBSL2 = 2600 m2

BSL3 = 2900 m2BSL4 = 100 m2 (400m2)

Animal Facility BSL3 = 955 m2

BSL4 = 127m2

Slide4

Construction and Maintenance costs

60 F/T Engineering staff

10 Microbiological Security Staff

($1M annually)

$6.8M annual maintenance & running cost $15M

/yr depreciation $25M engineering upgrade just completed focused on control and monitoring

ESB CMS

1

2

3

4

5

Machine Hall

Admin

CMS

L5 Plant Room

3

5

5

Server Rm North

Server Rm South

Slide5

Construction and Maintenance costs

Changing standards will require additional & significant investment

30 autoclaves to be refurbished or replaced ($5M-$15M)

Laboratory has operated continuously since opening

Science mission requires continuous operation during refurbishment Construction costs while operating $$$$

Slide6

BiosecurityPerimeter fence, box within box, infrared cameras

Dual access controls &

Cyberlocks

Critical Infrastructure protection branch

All AAHL staff with security access are ASIO clearedCSIRO.

Greg Smith Istanbul July 2011

CWA 15793

Slide7

Environmental issuesOriginally built to provided diagnostic capacity and vaccine production facilities for FMDV

FMDV has never been introduced to the lab

Local council regulati

ons prevent residents keeping cloven hoofed animals within 5 kilometres.

Staff not permitted to live on farm7 day exclusion for all staff and visitors

Greg Smith Istanbul July 2011

Slide8

TrainingStructured competency based training

Must first complete all BSL3 training and be signed off as competent to work at BSL3/4

Dedicated training lab

All routine and emergency procedures in training labSupervisors sign off BSL4 competency

CSIRO Greg Smith Istanbul July 2011.

Slide9

Strategies to manage infected individuals

Medical Advisory Committee

State Chief Health Officer

State Chief Veterinary Officer Local General PractitionerInfectious Disease PhysicianAll incidents referred to MAC

Home quarantine or admission to ID wardCSIRO. Greg Smith Istanbul July 2011

Slide10

Community RelationsDedicated Media Officer

Active engagement of public including schools

Tours for key State and Federal politicians

Facilitate media coverage (60 minutes, Catalyst etc.)Helps to have a long record >25 yrs of safe operation within the communityCSIRO.

Greg Smith Istanbul July 2011

Slide11

Maximising the investment;

reducing the risk

$10M to convert existing facility to specialised BSL3 and BSL4 lab space

Available to scientists across Australia and globallyGovernment, academic or commercial clients

Existing & proven systems and experienced staff

CSIRO Greg Smith Istanbul July 2011.

Slide12

Thanks for your attention!

CSIRO.

Greg Smith Istanbul July 2011