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Navarra(2013) Infective Versus Libman Sacks Endocarditis In Systemic Lupus Erythematosus. progressively improved.Penicillin and gentamycin were continued suggestive of cardiac valvular disease also conrmed by ultrasonographic within the past year and history of fever in the immediate past, the echocardiographic nding, she fullled 1 major criteria for infective as minor criteria making the diagnosis of possible infective endocarditis endocarditis e dilemma then was whether to treat for infective endocarditis or not. Libman Sacks endocarditis was rst described by Emanuel Libman and Benjamin Sacks in 1924 [4]. It is also known as verrucous, marantic, or non-bacterial thrombotic endocarditis. e lesions primarily consists of accumulations of immune complexes and mononuclear cells.ese subendothelial deposits may eventually lead valve followed by the aortic valve.Libman Sack lesions are associated antiphospholipid syndrome [5]. Cerebral thromboembolism remains remains Characteristic valvular pathology can also distinguish infective endocarditis vegetations from Libman Sacks endocarditis but this may irregular masses on the valve cusps that can extend onto the cords.cords. e vegetations seen on the patient’s echocardiogram were on the anterior and posterior mitral valve leaets but the exact size and extent of involvement on the leaets could not be distinguished.   Laboratory parameters can also be useful in distinguishing infective emphasized 3 laboratory tests namely, white blood cell (WBC) count, cell (WBC) count, WBC is expected to be low in SLE are and elevated in infection. CRP is usually signicantly elevated in infection, although some elevation may also be seen in SLE disease activity.Elevated antiphospholipid antibody laboratory work-up showed markedly elevated CRP, slightly elevated Ruiz-Irastorza, G. Khamashta M (2012) Cardiopulmonary Disease in SLE. Farzaneh-Far A, Roman MJ, Lockshin MD, Devereux RB, Paget SA, et al. (2006) Relationship of antiphospholipid antibodies to cardiovascular manifestations of Habib G, Hoen B, Tornos P, Thuny F, Prendergast B, et al. (2009) Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Cranial MRI showing enhancing foci in the anterior aspect of the Figure 2: 2D-Echo showing mitral valve thickening. Figure 3: TEE showing mitral valve vegetation. Salvador MTE, Navarra SV (2013) Infective Versus Libman Sacks Endocarditis In Systemic Lupus Erythematosus. Rheumatol Curr Res Libman-Sacks endocarditis in systemic lupus erythematosus: prevalence, MT, Gerdts E (2008) Libman-Sacks endocarditis and cerebral G (2003) Valvular and Endocardial Diseases of the Heart. UIC GE (2008) Establishing the diagnosis of Libman-Sacks endocarditis in Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection Undescribed Form of Valvular and Mural I, Tektonidou MG, Vasilliou VA, Samarkos M, Votteas V, et al. (2007) This article was originally published in a Orthopedics and Rheumatology: Case Reports Luke’s Medical Center and College of Medicine Manila, Philippines Rheumatol Curr Res Rheumatology, an open access journal Rheumatology and Clinical Immunology, University of Santo Tomas Hospital, Manila Philippines, USALibman Sacks endocarditis is a rare cardiac manifestation of Systemic Lupus Erythematosus (SLE). Cardiac valve vegetations may also be due to infective endocarditis especially in patients with risk We report a case of stroke in an SLE patient with positive anti-phospholipid antibodies and echocardiography A 33-year old female with stable SLE for 5 years on hydroxychloroquine and prednisone 5 mg/day presented with diplopia and intermittent fever of 2 weeks duration. She has had recurrent throat and gingival infections in the past year treated with antibiotics. Physical exam disclosed right lateral rectus and left medial rectus palsy, grade 3/6 holosystolic apical murmur, and livedo reticularis. Hemoglobin was 9.2 g/dl, and erythrocyte sedimentation rate (ESR) Michael Thomas E Salvador, Rheumatology and ClinicalImmunology, University of Santo Tomas Hospital, Manila, Philippines, USA, E-mail: Salvador Navarra SV (2013) Infective Versus Libman Sacks Endocarditis In Systemic Lupus Erythematosus. Rheumatol Curr Res S16: 003. 10.4172/2161-1149.S16-003, et al. This is an open-access article distributed unrestricted use, distribution, and reproduction in any medium, provided the Libman Sacks endocarditis, are present in 1 on every 10 SLE patients [1]. e diagnosis of Libman Sacks endocarditis becomes challenging, Rheumatology: Cu Current Research Salvador and Navarra, Rheumatol Curr Res 2013, S16 Case Report Rheumatol Curr Res ISSN: 2161-1149 Rheumatology, an open access journalOrthopedics and Rheumatology: Case Reports