PDF-Hazard ratios are commonly used when presenting results in clinical trials involving survival
Author : natalia-silvester | Published Date : 2014-12-13
They should not be considered the same as relative risk ratios When hazard ratios are used in survival analysis this may have nothing to do with dying or prolonging
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Hazard ratios are commonly used when presenting results in clinical trials involving survival: Transcript
They should not be considered the same as relative risk ratios When hazard ratios are used in survival analysis this may have nothing to do with dying or prolonging life but r eflects the analysis of time survived to an event the event may in some i. Bhanukiran . Vinzamuri. (bhanukiranv@wayne.edu). Yan Li (rockli_yan@wayne.edu). Chandan. K. Reddy(reddy@cs.wayne.edu). Index of presentation. Introduction. Problem Description. Cox Regression. Regularized Cox Regression. Saturday June 2, 10:15am-12:00pm. Kristin Rankin, PhD. Research Assistant Professor. Division of Epidemiology and Biostatistics. University of IL School of Public Health. Training Course in MCH Epidemiology. Ziad. . Taib. March . 3, 2014. I The log-rank test. INTRODUCTION TO SURVIVAL TIME DATA. ESTIMATING THE SURVIVAL FUNCTION. THE LOG RANK TEST. Survival Analysis. Elements of Survival Experiments. Event. Cynthia M. Otto, DVM, PhD DACVECC. Associate Professor of Critical Care. What is a clinical trial?. A prospective evaluation in which the factor of interest is controlled by the investigator. RANDOMIZATION. Ho - this hypothesis holds that if the data deviate from the norm in any way, that deviation is due strictly to chance.. Alternative hypothesis. Ha - the data show something important.. Doing decision = accept/reject Ho (the decision centers around null hypothesis). Susan S. . Ellenberg. , Ph.D.. University of Pennsylvania. SCT/ICTMC Joint Meeting. Liverpool, UK. May 8, 2017. CLINICAL TRIALS TIMELINE. 1948: First randomized clinical trials of modern era. 1962: Amendments to U.S. Food, Drug and Cosmetic Act requiring demonstration of efficacy as well as safety. Hypothesis Testing. A statement has been made. We must decide whether to . b. elieve it (or not). Our belief decision must ultimately stand on three legs:. What does our general background knowledge and experience tell us (for example, what is the reputation of the speaker)?. CLINICAL TRIALS IN THE TWENTY-FIRST CENTURY: ONGOING CHALLENGES AND EMERGING ISSUES Susan S. Ellenberg , Ph.D. University of Pennsylvania SCT/ICTMC Joint Meeting Liverpool, UK May 8, 2017 CLINICAL TRIALS TIMELINE Susan S. . Ellenberg. , Ph.D.. University of Pennsylvania. SCT/ICTMC Joint Meeting. Liverpool, UK. May 8, 2017. CLINICAL TRIALS TIMELINE. 1948: First randomized clinical trials of modern era. 1962: Amendments to U.S. Food, Drug and Cosmetic Act requiring demonstration of efficacy as well as safety. Christopher S. Coffey. Professor, Department of Biostatistics. Director, Clinical Trials Statistical and Data Management Center. University of Iowa. May 28, 2019. In this webinar, we will:. Discuss the importance of adequate study planning for small clinical trials. Professor Julia . Brown. Leeds Institute of Clinical Trials Research, University of Leeds. Introduction. First clinical trial in 1747, James Lind. Clinical trials are gold standard for the evaluation of new treatments/interventions in health care . Clinical trials . are required in the development of . new . medicines and improved treatments . for . patients. . The . information that clinical trials generate on the efficacy and safety of . treatments . Helen Hill. Senior Regional Advisor Clinical Trials . hhill. @liv.ac.uk. www.ctrc.org.uk. . Specialist. . units . to . design, conduct, analyse and publish clinical trials and other well-designed studies. . Tony Durkee, PhD. Coordinator for Clinical Trial Reporting. Compliance & Data Office (CDO), Research Support Office (RSO). Karolinska . Institutet. (KI). Email: tony.durkee@ki.se. . 6/17/2021. Tony Durkee.
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