PPT-RESTING MEMBRANE POTENTIAL

By Dr Ayisha Qureshi Assistant Professor Physiology MBBS MPhil OBJECTIVES By the end of this lecture you should be able to Define Nernst potential Use the Nernst equation to calculate the values of Nernst potential for Na K amp Cl. . By Dr. . Vani. Gupta. 2. “Polarity” . of the . membrane. Na. +. K. +. Mg. 2+. Ca. 2+. H. +. HCO. 3. -. Cl. -. SO. 4. 2-. PO. 3. -. protein. inside. (in mM). 14. 140. 0.5. 10. -4. (pH 7.2). 10. بسم الله الرحمن الرحيم. Objectives. Define Membrane . Potential. ?. Describe the electrical potential across the cell membrane.. Explain the Resting . Membrane and its cause . (Concentration . and . Resting Membrane Potential. Part 2. . . Action potential. Action Potential . An . action potential. can be thought of as the “firing” of the neuron.. Action potentials will . propagate . down the length of a neuron’s axon. How signals are sent through the nervous system. Synapse. Synapse. = Junction between . two. connecting neurons. Synaptic cleft-between the neurons,. signal has to go across this space. Signals need to be sent . . By Dr. . Vani. Gupta. 2. “Polarity” . of the . membrane. Na. +. K. +. Mg. 2+. Ca. 2+. H. +. HCO. 3. -. Cl. -. SO. 4. 2-. PO. 3. -. protein. inside. (in mM). 14. 140. 0.5. 10. -4. (pH 7.2). 10. بسم الله الرحمن الرحيم. Objectives . Define graded potential and action potential.. Describe characteristics of graded potential. C. ompare . between the different phases of excitability during a nerve action . Pratt & . Cornely. , Ch. 9. Thermodynamics. Membrane potential—volts. For +1 ion, potential = 0.058V(log. ). If potential is negative, the inside of cell is more negative.  . Energetics of Transport. 11.4 Membrane Potentials. Like all cells, neurons have a . resting membrane potential. Unlike most other cells, neurons can rapidly change resting membrane potential. Neurons are highly excitable. © 2016 Pearson Education, Inc.. To understand what a . resting potential . is.. To understand how a . resting potential . is established in a neurone.. To understand what an . action potential . is.. Welcome to Hell… Population = You. Membrane Properties chemical and electrical properties of biological membranes Jim Huettner Lecture Overview Selective permeability Osmolarity and osmotic pressure Ionic gradients Electrical properties: resistance and capacitance logical Basis of Behavior. jp-rosenfeld@northwestern.edu. We study how the brain makes mind and behavior. METHODS (in oversimplification terms):. 1.. Lesions. (Ablation): Oldest Method; 2 ways:. a) Natural: Take them as they come (bullet holes, tumors; “Neuropsychology”.) . Advanced MRI Section, LFMI, NINDS, NIH. Outline. Background. Properties. Analysis. Noise & variability. Summary. Resting-state fMRI. +. no task or stimuli. typical instructions: keep eyes closed, or keep them open/fixation; don’t fall asleep; let your mind freely wander..... Dept of . Zoology,MRGC. , . OBJECTIVES:. TO STUDY. ............ TYPES OF NEURONS. FUNCTIONS OF NERVOUS SYSTEM. IMPORTANT TERMS. PHYSIOLOGY OF NERVE IMPULSE. 3. rd. Semester Zoology (Major)-CC IV: Controlling and Coordinating System :Nervous system: Physiology of nerve impulse conduction. Cell body —> 5 - 7 dendrites —> Long, fibrous axon —> divides into terminal branches —> each ends in a terminal knob. . Myelin sheaths - formed by Oligodendrocytes . 4 zones to a nerve fiber .