PPT-Substitution and Elimination

Competing Reactions Alkyl halides can react with Lewis bases by nucleophilic substitution andor elimination C C H X Y C C Y H X C C H Y X . Structures and Properties. Halogen is connected to a tetrahedral carbon. The carbon-halogen bond is polarized with the carbon having a partial positive charge and the halogen having a partial negative charge. In addition to substitution, alkyl halides can also undergo elimination reactions, which lead to the formation of alkenes.. As with substitution reactions, elimination reactions come in two mechanistic types:. 7-7. Strong bases effect bimolecular elimination.. At higher concentrations of strong base, the rate of alkene formation becomes proportional to both the starting halide and the base.. Under these conditions the second order kinetics are called bimolecular elimination or E2.. Eraser Game. !. A boat traveled 210 miles downstream and back. The trip downstream took 10 hours. The trip back took 70 hours. What is the speed of the boat in still water? What is the speed of the current?. Substitution and Elimination at C(sp. 3. )-X . σ. bonds. Addition of . Nuclephiles. to Electrophilic . π. bonds. Substitution . at . C(sp. 2. )-. X . σ. . bonds. Base-promoted Rearrangements. Chapter . Advanced Algebra. Write a System of Equations and Solve. . You buy 5 pairs of socks for $19. The wool socks cost $5 per pair and the cotton socks cost $3 per pair. How many of each kind of sock did you purchase?. Each team during a game of football is able to make up to three substitutions. In association football a substitute is a player brought onto the field for an existing player, generally because they are tired, fatigued or under performing. A player may only be substituted when the play stops and the referee gives the signal to notify they are allowing this to happen. The player must only enter the field at the half way line and wait for their team-mate to leave the football pitch. The player who has left the field is not allowed to return to the pitch for the duration of the match. . Lecturer: . Jomar. . Fajardo. . Rabajante. 2. nd. . Sem. AY . 2012-2013. IMSP, UPLB. Numerical Methods for Linear Systems. Review . (Naïve) Gaussian Elimination. Given . n. equations in . n. variables.. Generic Equation: Swap. R-X + Nu: .  R-Nu + :X. -. The problem lies in the mechanism.. Importance of Alkyl Halides. Precursor to many others. NUCLEOPHILIC SUBSTITUTION. Theory. . - nucleophile means ‘liking positive’. A boat traveled 210 miles downstream and back. The trip downstream took 10 hours. The trip back took 70 hours. What is the speed of the boat in still water? What is the speed of the current?. Solve by substitution. Unific. ation. . and . Resolution. ). Dr Youcef Djenouri. djenouri@imada.sdu.dk. D. M552: Part . 2 . Programing. . Logic. 2017-2018. Substitution: . Definition. (1/2). Substitution. . θ . is . an operation allowing . Halogen is connected to a tetrahedral carbon. The carbon-halogen bond is polarized with the carbon having a partial positive charge and the halogen having a partial negative charge. The size of the halogen increases as you move down the group. Objectives. Define elimination as it relates to infectious diseases. Understand the gaps in the current cascade of care for HCV. Identify interventions required to achieve HCV elimination in a defined population. David L. Thomas, MD, MPH. Professor of Medicine. The Johns Hopkins Medical Institutions. Baltimore, Maryland . Financial Relationships With Commercial Entities. Dr Thomas has no relevant financial affiliations to disclose. (Updated 11/12/18).