PPT-Computational Analysis of Kinesin Mutations Implicated in Hereditary Spastic Paraplegias

Shaolei Teng Department of Biology Howard University Rocky 2019 Hereditary Spastic Paraplegia HSP and Kinesin Mutations HSPs rare genetically neurodegenerative disorders characterized various neurological features including progressive spastic weakness urinary sphincter dysfunction extra pyramidal signs and . Publizieren ist ein essentieller . Bestandteil des. wissenschaftlichen Arbeitens. Publizieren. Publizieren ist ein essentieller Bestandteil beim. wissenschaftlichen Arbeiten. Publizieren ist die „Pflicht“. Publizieren ist ein essentieller . Bestandteil des. wissenschaftlichen Arbeitens. Publizieren. Publizieren ist ein essentieller Bestandteil beim. wissenschaftlichen Arbeiten. Publizieren ist die „Pflicht“. TULIP. Theory. T. otal Hereditary Depravity. . . Man’s nature is corrupt. . No ability to choose good over evil. U. nconditional Election. . . God’s choice – A few saved. . All others excluded from salvation. Polyposis. Syndromes in the Mediterranean Region. Thomas M Attard MD FAAP FACG. Associate Professor, Pediatrics, Gastroenterology, University of Malta, Malta. . Consultant Gastroenterologist Children’s Mercy Hospital, Kansas MO, USA.. UterineCancerMost people develop uterine cancer by chance or as a result of risk factors that occur over the course of a lifetime However up to 10percentof people who are diagnosed with uterine cancer Assist. . Prof.. , PMR. MBBS VI Sem. – 25/04/2019. DEFINITION. C. linical . syndrome . has three important criteria . -. 1. Motor dysfunction.. 2. Non progressive . brain. damage.. 3. Affecting an immature developing brain.. Session I . – How things move inside a cell. 2/7/14. A typical highway road map. http://www.youtube.com/watch?v=wJyUtbn0O5Y. Transport road map of a cell. Watch (Cell Biology). Measure and Quantify (Systems/Quantitative Biology, Physics). Definition. A non-progressive, non-hereditary disorder of movements and posture occurring in a maturing brain. Main features include . Impairment of motor and posture function. Non-progressive and nonhereditary. June2009 www.hkmj.org 217 Case report We report a 38-year-old Chinese man (IV-2) with hereditary spastic paraplegia (HSP). He developed bilateral lower limb weakness in his late twenties and within Prostate cancer is the most common cancer in males . M ost men develop prostate cancer by chance or as a result of risk factors that occur over the course of a lifetime. However, approximately 10 pe Posted on Friday, March 12, 2004 DURHAM, N.C. -- Two seemingly disparate hereditary syndromes actually stem, in some patients, from a uke University Medical Center genejuvenile polyposis -- characteri been thought to reflect the actions of kinesin [ 11, whereas motility in the oppo- site direction has been attributed to dynein [2]. Several predictions emerge from the kinesin/dynein model for bidir Autosomal dominant HSP Spastic gait (SPG) locus OMIM# Clinical Syndrome SPG3A 182600 Atlastin Uncomplicated HSP: symptoms usually begin in childhood (and may be non - progressive); symptoms may a Dr . Laxmi. Kant . Pandey. ROLE OF KINESIN & DYENIN. Retrograde Movement. Anterograde. Movement. KINESIN (. Mechanochemical. enzyme). Kinesin. is the motor . protien. .. So far 14 classes of .