Anke Rohwer Andrew Booth Lisa Pfadenhauer Louise Brereton Ansgar Gerhardus Kati Mozygemba Wija Oortwijn Marcia Tummers Gert Jan van der Wilt Eva Rehfuess ID: 815376
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Slide1
Building a logic model of reinforced models of palliative care
Anke Rohwer, Andrew Booth, Lisa Pfadenhauer, Louise Brereton, Ansgar Gerhardus, Kati Mozygemba, Wija Oortwijn, Marcia Tummers, Gert Jan van der Wilt, Eva Rehfuess
The INTEGRATE-HTA project is co-funded by the European Union under the Seventh Framework Programme (Grant Agreement No.
306141)
Slide2The logic of
logic models
Slide3The
Logic of Logic ModellingComplexity of health technologies and systems
Strong assumptions about the structure, content and objectives of a health technology as well as its implementation
Negligence
of system within which the intervention is intended to act and the potential interplay and co-evolution
Describes
components
of complex interventions and relationships between them
Makes underlying theories of change and assumptions about causal pathways explicit
Describes interactions between the intervention and the system within which it is implemented
Logic Models
“…
a graphic description of a system … designed to identify important elements and relationships within that system”
.
Added value of using logic models in systematic reviews
Scoping the review
Refining review question
Deciding on lumping or splitting a review topic
Identifying intervention components
Defining and conducting the review
Identifying relevant study inclusion/exclusion criteria
Guiding the literature search strategy
Explaining the rationale behind surrogate outcomes used in the review
Justifying need for subgroup analyses (e.g. age, sex/gender, socioeconomic status)
Making the review relevant to policy and practice
Structuring reporting of results
Interpreting results based on intervention theory and systems thinking
Illustrating how harms and feasibility are connected with interventions
Interpreting results based on intervention theory and systems thinking
(Anderson et al, 2011)
Slide5Method of development
of logic models: four step process(i) systematic searches for published examples of logic models(ii) searches for existing guidance on the use of logic models in primary research, SRs and HTAs(iii) development of two draft templates for system-based and process-orientated logic models and (iv) application of these templates in three SRs and one HTA of different complex health technologies.
Slide6Logic models
in HTA and Systematic ReviewsHTA/SR research
question
Check
literature
for
published
logic models
Adoption of published
logic model
Adaptation
of logic
model
De
novo
logic
modelType of
logic model
Subtype of logic modelA-priori logic modelIterative logic model
Staged
logic
model
Process-based
logic
model
System-
based
logic
model
Slide7Three types of logic model
Label
Meaning
Type
A priori logic model
A logic model that is specified as close to the inception of an HTA or SR as scoping the literature and/or stakeholder consultation permit and that remains unchanged during the HTA/SR process.
Iterative logic model
A logic model that is subject to continual modification and revision throughout the course of an HTA or SR.
Staged logic model
A type of iterative logic model that pre-specifies points at which major data inputs are anticipated to prompt a subsequent version of the logic model, thereby increasing transparency and
minimising
problems with version control.
Slide8Subtype: System-based
logic model
Slide9Subtype: Process-oriented
logic model
Slide10Populating the
logic model template
SAP and expert input
Discussion
within
team
Literature
review
Logic models
in the INTEGRATE-HTA Process
Slide12INTEGRATE-HTA model
Slide13Ideal application of
Logic Models in INTEGRATE-HTA: Staged system-based logic model
Based on the agreed HTA question and a combination of team discussions, literature and SAPs.
Initial Logic Model
1
Based on an analysis of context and implementation, patient preferences and moderators of treatment.
Iteration 1
2
Based on the results of the effectiveness review and economic assessment, as well as insights generated through the socio-cultural, ethical and legal assessments.
Iteration 2
3
Based on any additional findings generated through an assessment of context and implementation.
Final Logic Model
4
Slide14System-based logic model of reinforced and non-reinforced home-based palliative
care (Brereton et al. 2015)
Slide15Discussion
Added valueGetting team on same pageIntegrating various types of evidence/knowledgeStructuring subsequent SR/HTA processGraphical means of communicationStrenghts and limitations:parallel development of methods and application in demonstration HTAEmpirical testing in various SREach type and subtype of logic models has its specific strengths and limitations
Slide16Conflict of Interest
The authors have no conflicts of interest to declare
<DISCLAIMER: The sole responsibility for the content of this presentation lies with the authors. It does not necessarily reflect the opinion of the European Union. The European Commission is not responsible for any use that may be made of the information contained therein.>
Slide17References
Anderson LM, Petticrew M, Rehfuess E, Armstrong R, Ueffing E, Baker P, et al. Using logic models to capture complexity in SRs. Research Synthesis Methods. 2011;2(1):33-42.Rohwer, A., Booth, A., Pfadenhauer, L., Brereton, L., Gerhardus, A., Mozygemba, K., Oortwijn, W., Tummers, M., Van Der Wilt, G.J., Rehfuess, E. (2015) Guidance on the use of logic
models
in
health
technology assessments of complex interventions [Online].
Available from: http://www.integrate-hta.eu/downloads/