PPT-Anxiolytic

action of Sri Lankan Orange Pekoe grade of black tea Camellia sinensis L in rats TBS Muthunayake 1 WD Ratnasooriya 1 EK Indeesha 1 CDT Ratnasooriya. Anxiolytics. :. Benzodiazepines & others. Tracy A. Womble, . Ph.D. Florida A&M University . College of Pharmacy and Pharmaceutical Sciences. SEDATIVE-HYPNOTICS . History of Sedatives. Alcohol, the oldest known sedative. These are anti-anxiety agents used to control moderate or severe tension. .  . Classification. :. Benzodiazepines (BZP).. Propanediol. . carbamate. .. Azaspirodecanediones. .. 1. CNS depressants. They are the drugs of choice used as:. Kelsey I. . Landaverde. , Stacey L. . Kirkpatrick, . Lisa R. . Goldberg, . Camron D. . Bryant. Laboratory . of Addiction Genetics, Department of Pharmacology and Experimental Therapeutics and Psychiatry, Boston University School of Medicine. Anxiolytic. and Hypnotic drugs. Anxiety is unpleasant state of tension and fear that seems to arise from unknown source.. The symptoms of severe anxiety are similar to those of fear (such as tachycardia, palpitation) and involve sympathetic activation.. mice. Abu Montakim Tareq. 1. , . A.S.M. . Ali Reza. 1,. *, . Talha. Bin . Emran. 2. ,. *. 1 . Department of Pharmacy, International Islamic University Chittagong, . Kumira. , Chittagong-4318, Bangladesh; . of black tea . (Camellia . sinensis. L.) in rats. T.B.S. Muthunayake. 1. , W.D. Ratnasooriya. 1. , E.K. Indeesha. 1. , C.D.T. Ratnasooriya. 1. 1 Department of Zoology, University of Colombo, Colombo 03.. Mucuna pruriens . in Experimental Model of Swiss. Albino Mice. Anjula Sachan, Sarvesh Kumar, Hemant Singh, Pratap Shankar, Dheeraj Kumar, Amod Kumar Sachan, Rakesh Kumar Dixit. The usage of benzodiazepines, the major class of anxiolytic drugs is invariably accompanied by many side-effects like sedation and muscle relaxation leading to incoordination of movements. Search for novel anxiolytic agents have identified flavonoids as potential compounds devoid of these adverse effects. Mucuna pruriens commonly known as cowhage plant has been claimed to possess various beneficial effects like anti-parkinsonian, anti-tumor, neuroprotective, antioxidant, anti-diabetic and antimicrobial activities. Previous studies have reported that Mucuna pruriens contains LDOPA and 5-hydroxy tryptophan (5-HT) as a major constituent with higher concentration in seeds. .