PPT-DNA-guided genome editing using the

Natronobacterium gregoryi Argonaute Feng Gao Xiao Z Shen Feng Jiang Yongqiang Wu amp Chunyu Han Gene E diting Tools Overview httpsenwikipediaorgwikiGenomeediting In order to do a targeted genome editing we need to make a double stranded breaks at specific sites within genome. Sequence Differences in the. Human . Transcriptome. Mingyao. Li. , Isabel . X. Wang. , . Yun. Li, . Alan . Bruzel. , . Allison L. Richards. ,. Jonathan M. . Toung. , . Vivian G. . Cheung. Mahnaz. . Of Which People, By Which People, For Which People?. Charis Thompson. Chancellor’s Professor . UC Berkeley / London School . of Economics. Washington, DC, December 2015. Consensus on Human . Germline. Fyodor D. Urnov, PhD. Project Leader and Senior Scientist, Sangamo BioSciences, Inc.. NAS International . Summit on Human Gene . Editing. December 3, 2015. Genome Editing . Is. In the Clinic. Fyodor D. Urnov, PhD. Alliance for Regenerative Medicine. NAS Public Meeting – February 11, 2016. 2. 2. ARM’s Role in the Sector. As the leading global advocate for the regenerative medicine and advanced therapies sector, ARM enables acceleration of research, development, investment and commercialization of transformational treatments and cures for patients worldwide.. Genome: the total number of genes in an individual.. Human Genome- approx. 20,000 genes on the 46 human chromosomes.. Human Genome Project (HGP). Ongoing effort to completely map and sequence our genome.. (before and after 2015). Second International Summit on Human Genome Editing . The University of Hong Kong . November 27-29 2018 . India specific Actions . And Advisory Options Related Human Genome Editing. DNA damage DNA gets damaged a lot ! DNA damage DNA gets damaged a lot! >200,000 events/human cell/day DNA damage Occurs 2 ways 1) spontaneously 2) mutagens : damage DNA Transposons Discovered by Barbara McClintock Extreme Photos – put yourself in a photo that seems impossible. Use your imagination. Use these example to help you out. Obscure Images – Think of something out of the ordinary seem real – In reality you are just combining 2 images.. Filipa Lopes. . “Plants for Life” International PhD Program – 2017. (course “Plant Biotechnology for Sustainability and Global Economy”). . What. . is. . plant. . breeding. ?. Is the art and science of changing certain traits of plants over time in order to introduce desired characteristics. Hardison. . Genomics 2_2. 1/7/15. 1. Y Chromosome. 3 billion bp = 3 Gb. Chr1 247 Mb. Chr12 132 Mb. Chr22 50 Mb. A human . genome (. male). The . genome. is . all the DNA. in a cell.. All the DNA on all the chromosomes. 12 – 13 November 2019, Singapore. www.gfbr.global.  .  .  .  . The GFBR. Funded by Bill & Melinda Gates Foundation, UK Medical Research Council, US National Institutes of Health, and . Wellcome. successfully applied to directly produce low-copy integrated transgenic lines in C. eleganss10]. High copy integrated arrays are prone to be silenced, yet low-copy transgenes permit relatively stable Ethics, governance and policy aspects of human genome editing research . . Maneesha S Inamdar. JNCASR, Bangalore. GFBR. 12-13 Nov 2019. Singapore. Maneesha S Inamdar. Professor and Chair. Molecular Biology and Genetic Unit. the. . Brazilian. . regulatory. framework: . can. . we. face . genome. . editing. ?. José Ricardo Jensen, DVM, Former Head, CEUAIB (IACUC - Instituto Butantan). Ricardo Palacios, Clinical R&D Manager - Division of Clinical Trials and Pharmacovigilance .