PPT-Viral hemorrhagic fevers (VHFs)

By Assis Prof Nader Alaridah MD PhD Overview Viral hemorrhagic fevers VHFs are a group of illnesses caused by four families of viruses Arenaviridae   Bunyaviridae Filoviridae and . In general the term viral hemorrhagic fever is used to des cribe a severe multisystem syndrome multisystem in that multiple organ systems in the body are affected Characteristically the overall vascular system is damaged and the bodys ability to reg In general infection with these viruses may cause serious illness with fever and damage to blood vessels affecting many organ systems Damage to the blood vessels can disrupt blood flow and cause severe bleeding Although some VHFs are mild illnesses Walter Dehority, M.D., MSc.. Outline. 1.) Introduction. 2.) The Major Players. A.) PFAPA. B.) Hyper IgD Syndrome. C.) Familial Mediterranean Fever Syndrome. D.) TRAP Syndrome. E.) Cyclic Neutropenia. Hemorrhagic stroke vs. ischemic stroke. Intracerebral hemorrhage. Occurs from rupture of cerebral vessels . Can be a result of high blood pressure. Ischemic Stroke. . Caused by the development of a thrombus and/or embolus. --potentially useful as a biological weapon attacking humans. --. presented by . Zilan. . Hu. Professor Dr. Jim Maruniak. Virology MCB 5505, Section . 4658. Introduction. Crimean-Congo . haemorrhagic. --potentially useful as a biological weapon attacking humans. --. presented by . Zilan. . Hu. Professor Dr. Jim Maruniak. Virology MCB 5505, Section . 4658. Introduction. Crimean-Congo . haemorrhagic. --potentially useful as a biological weapon attacking humans. --. presented by . Zilan. . Hu. Professor Dr. Jim Maruniak. Virology MCB 5505, Section . 4658. Introduction. Crimean-Congo . haemorrhagic. 1Diagnostic Capacity and 1Preparedness in the Wake of Recent Ebola and ZikaVirus Outbreaks23Dr Edgar Simulundu1 Prof Aaron S Mweene1Dr Katendi Changula1Dr Mwaka 4Monze2Dr Elizabeth Chizema3Dr Peter Mw Where are cases of viral hemorrhagic fever found Taken together the viruses that cause VHFs are distributed over much of the globe However because each virus is associated with one or more particular virus RNA by RT-PCR Positive Negative Indeterminate Pending Unknown Viral hemorrhagic diseasevirus identified by Culture Positive Negative Indeterminate Pending Unknown Viral hemorrhagic diseasevirus Picture: an Electron Micrograph of the Ebola VirusCourtesy: Centers for Disease Control and Prevention 2009 Special Pathogens BranchDivision of HighConsequence Pathogens and PathologyNational Center 150 Update on Tropical Fever Direct damage to the vascular system or the target organs, in�ammatory mediator induced injury and immune response are some of the mechanisms incriminated in th Page 1 of 2 1/16  Report Immediately: 800.472.2180 or 701.328.2378 Possible Bioterrorism Agents (CDC classified A, B or C Agent) Viral Hemorrhagic Fever  What is Viral Hemorrhagic Fever ? Vi : Guidance for Healthcare Providers Page 1 of 13 VDH/OEPI/DSI Revised February 2019 Virginia Department of Health Viral Hemorrhagic Fever : Guidance for Healthcare Providers Key Medical and Public