PPT-Web of Causality: Sepsis Mortality in Philadelphia

Melissa Lester Dr Matt Wray Department of Sociology Temple University Philadelphia PA What is Sepsis Bacteria or fungus enter bloodstream 2 Community or hospital acquired 3 Response by innate immune system to infections. `. Christa A. Schorr RN, MSN, FCCM. Assistant Professor of Medicine. Cooper Medical School of Rowan University. Director of Databases for Quality Improvement and Research. Program Director of Critical Care Clinical Trials . Adult Inpatients. Learning objectives. Recognise that sepsis . i. s a medical emergency. Identify the risk factors, signs and symptoms. Outline the escalation of the septic patient . Define the . initial management actions. Paediatric Inpatients. Learning Objectives. Recognise that sepsis . i. s . a medical emergency. Identify the . risk factors, signs and symptoms. Outline the escalation of the septic . patient. Define the initial A-G management actions. EM Student Lecture Series. CASE STUDY. A 53-year old woman presents complaining of several days of fever, generalized malaise, nausea & vomiting. She has a PMH of diabetes and HTN and takes . Glucophage. ACMQ. Pranavi Sreeramoju, MD, MPH. November 17, 2015. Sepsis. Systemic Inflammatory Response Syndrome (SIRS) . requires . the presence of two of the following four factors:. Temperature < 36.0 C or > 38.0 C. Dr. Vida Hamilton. National Clinical Lead Sepsis. www.hse.ie/sepsis. Sepsis - 2. A dysregulated immune response to infection. Regulated. Innate & Adaptive. Cellular: Dendritic cells, T-cells, B-cells. Early Goal Directed Therapy. and Beyond. Anthony J. Hericks, D.O.. South Dakota. ACP. Scientific Meeting. September 13. th. , . 2013. A clinician, armed with the sepsis bundles, attacks the three heads of severe sepsis: hypotension, hypoperfusion and organ dysfunction. . Objectives. “Sepsis is caused when the body’s . immune system becomes overactive in response to an infection. , causing inflammation which can affect how well other tissues and organs work.”. –National Institute for Health and Care Excellence Guidelines. P Llewellin. Aims. Briefly review the pathophysiology and effects of sepsis. Discuss contemporary definitions of sepsis. Understand the importance of early recognition of sepsis. Review the current management paradigms for sepsis . ©2019 CHA. Objectives. The learner will:. Verbalize understanding of the criteria for severe sepsis and septic shock. Explain the most common sources of infection for sepsis. Explain and demonstrate treatment of severe sepsis and septic shock using the three- and six-hour bundles. CASE STUDY. A 53-year old woman presents complaining of several days of fever, generalized malaise, nausea & vomiting. She has a PMH of diabetes and HTN and takes . Glucophage. and . Lisinopril. Assistant Professor of Medicine. Pulmonary, Allergy, & Critical Care Medicine. Duke University Medical Center. Disclosures. None. Objectives. Define sepsis. Learn basic sepsis pathophysiology. Understand central venous O. National Clinical Lead Sepsis. www.hse.ie/sepsis. Sepsis. ‘Final . common pathway for death from . infection’. National Awareness Survey 2016. 25% Doctors . & . 29% Nurses interviewed. . . Sepsis,. . TNF-α. . Association. . with. . Mortality. . but. . not. . Sepsis. . Severity. . or. . Infection. . Source:. . a. . Systematic. . Review. and. . Meta-analysis. Amal. . A..