PPT-Statistical Genomics Zhiwu Zhang

Washington State University Lecture 26 Bayesian theory Outline Concept development for genomic selection Bayesian theorem Bayesian transformation Bayesian likelihood Bayesian alphabet for genomic selection. Bioinformatics and Genomics. Applications:. Personalized cancer medicines. Disease determination . Pathway Analysis. Biomarker Discovery . An Interesting Point. “One . article estimated that the output from genomics may soon dwarf data heavyweights such as . NGS analysis. Ravi Madduri. madduri@anl.gov. Joint work with Paul . Davé. , Lukasz . Lacinski. , Alex Rodriguez, . Dinanath. . Sulakhe. , Ryan Chard and Ian Foster. Globus Genomics is developed, operated, and supported by researchers, developers, and . CHAPTER 338Worldwide Scientific Capacity for DevelopmentInadequate Governance Contributes to Failure of Diffusion ofGlobal Governance to Promote Global Public GoodsNeed for Global Governance for Genom Overview and Capabilities: . . High Throughput Sequencing Facility (HTSG). Functional Genomics M. ammalian Genotyping Core (MGC). Corbin Jones. Faculty Director. Piotr . Meiczkowski . Technologies . What is Structural Genomics ?. Is the process of high-. throughtput. determination of 3-D structures of Biological macromolecules. What is the Goal of Structural Genomics ?. Provision of enough structural templates to facilitate homology modeling of most proteins.. Genomics and Society Nature (2014) “ …disorders not readily explained by standard tests can sometimes be diagnosed through genome sequencing and analysis.” The Origin of “Genomics& . Carl Pray. 1. Can advances in biology transform Asian agriculture? Challenges are large. Food production . Productivity growth . Crises – . Biological -Africa Swine Fever, corn stalk borer, fall armyworm, wheat rust. What . is . Functional. . Genomics?. RNA . Transcription/Gene. . Expression. Measuring Gene. . Expression. Microarrays. High-throughput. . Sequencing. Transcriptional. . Regulation. Transcription. Dongjun Chung. 7/13/2015. Table of Contents. Logistic regression in statistical genetics.. Negative Binomial . regression in statistical genomics.. Logistic Regression:. Statistical Genetics. The Story begins with…. . . Shawneequa L. Callier, JD, MA . Associate Professor. Clinical Research and Leadership. School of Medicine and Health Sciences. George Washington University. Special Volunteer. Center for Research on Genomics . Bella Starling. Director of Public . Programmes. , CMFT. Wellcome. Trust Engagement Fellow. About me. Career. Scientist (neuroscience, genetics, stem cells). Science writer. Biomedical ethics. Public engagement, . Ian Green. Clinical Engagement and Education Business Manager. Strategy. Work undertaken by Genome One (part of the . Garvan. Institute). Work underway. Completion date . –. 17. th. , March 2017. Ravi Madduri. madduri@anl.gov. Joint work with Paul . Davé. , Lukasz . Lacinski. , Alex Rodriguez, . Dinanath. . Sulakhe. , Ryan Chard and Ian Foster. Globus Genomics is developed, operated, and supported by researchers, developers, and . Elected member: International Statistical Institute. US Chair: International Statistical Literacy Project. 17 July 2014 ICOTS-9. www.StatLit.org/pdf/2014-Schield-ICOTS-Slides.pdf. ODYSSEY: A Journey to .