Prolotherapy an injectionbased regenerative therapy and guided physical therapy PT are safe evidencebased modalities but have not been compared S tudy question Among adults with tennis elbow what is the effect of prolotherapy PT and the two combined on diseasespecific q ID: 779227
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Slide1
The Research Question
Lateral epicondylosis (tennis elbow) is common, debilitating and often refractory to routine care.
Prolotherapy
, an injection-based “regenerative” therapy, and guided physical therapy (PT) are safe, evidence-based modalities, but have not been compared.
S
tudy question
:
Among
adults with tennis elbow, what is the effect of prolotherapy, PT and the two combined on disease-specific quality of life as assessed by a validated questionnaire?
Slide2Research Design and Method
Design: 12 month
randomized controlled trial
(N=120).
Participants: Adults with chronic tennis elbow.
Intervention: Participants were allocated to:
4
monthly sessions
of prolotherapy with hypertonic dextrose, OR…
4 weekly sessions of PT, OR…
Prolotherapy and PT combined.
Assessment: Patient-Rated
Tennis Elbow Evaluation (PRTEE) questionnaire. The outcomes assessor was blinded to group.
Slide3What the Research Found
120 participants
Adherence
to treatment and 12-month questionnaire adherence were
high: 93
% and 88% respectively.
All
groups reported PRTEE score improvements of approximately 28 points on this 100-point
scale.
Meets clinical importance standard.
T
here
was not a difference between
groups at 12 months;
combined care did not improve outcomes
.
Participants in all groups were
satisfied.
T
here
were no adverse events.
Slide4What this means for Clinical Practice
Prolotherapy,
PT and combined therapy resulted in safe, significant, substantial and sustained improvement of PRTEE-based elbow pain and function by 52 weeks.
Clinicians
can feel comfortable recommending prolotherapy and supervised PT to patients who are refractory to other non-surgical care
.
Combination therapy did not add improvement to either therapy alone.