National Social Life Health and Aging Project NSHAP Katie ODoherty Outline 01 NSHAP Background 02 Interviewer Administered Biomeasures 03 SelfAdministered Biomeasures NSHAP Background ID: 1001166
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1. Biomeasure Collection for theNational Social Life, Health,and Aging Project (NSHAP)Katie O’Doherty
2. Outline01NSHAP Background02Interviewer Administered Biomeasures 03Self-Administered Biomeasures
3. NSHAP BackgroundNational Social Life, Health and Aging Project (NSHAP)Longitudinal study of social life and healthNational area probability sample of older adultsInterviewed approximately every five years.2005Round 12010Round 22015Round 32021Round 4
4. NSHAP BackgroundData collection designTraditional Approach: In-Person InterviewRounds 1 - 4Conducted by field interviewer at respondent’s homeSurvey + minimally invasive biomeasures2-hour interview$100 incentive
5. NSHAP BackgroundNew Approach: Remote interviewAdded in Round 4 for half of sample1 hour survey: web, phone or paper-and-pencilAt end of survey, invited to receive BioBox (self-collected biomeasures)BioBox mailed to respondentInterviewer provides support and prompting$100 incentive
6. Biomeasures collected*SensesSmellTasteTouchVisionBodyWeightWaist HeightBlood pressureActivityChair stand10-foot walkAccelerometerBioSamplesSalivaBloodVaginal sample*Not all measures are collected in every roundNSHAP Background
7. Interviewer Administered Biomeasures
8. Interviewer administered biomeasuresCollected biomeasures as part of in-person interview since round 1Prioritized selecting minimally invasive biomeasures that could be collected by an interviewer in the homeBiomeasures selected in relation to the specific aims and research questions
9. Interviewer administered biomeasuresOperational considerationsAdapt to in-home collectionRespondent and Interviewer burdenOperational feasibility Cooperation rates and data qualityHuman subjects and consentDevelop step-by-step protocols
10. In Person biomeasure cooperation ratesBiomeasureRound 1Round 2Round 3 Weight98%98%98%Waist97%98%97%Height99%98%99%Blood Pressure98%98%98%10 Foot Walk94%96%98%Chair Stands94%94%98%Smell98%96%96%Taste96%n/an/aDistance vision96%n/an/aSaliva89%95%91%Vaginal Swabs68%73%n/aBlood Spots85%92%92%Accelerometern/a78%84%
11. Self-Administered Biomeasures
12. Remote data collection backgroundNew to R4: NSHAP Remote Data Collection Protocol
13. BioBox overviewNSHAP BioBoxBioBookletBioBoxSpecimen storageSupply Box
14. BioBooklet overviewSimple step-by-step instructionsRecord answersOrganized and color coded to help them find the supplies in the BioBoxBioBooklet
15. Biobox: interviewer support and promptingBiobox Follow-Up CallsShipping NotificationBrief check-in to notify respondents when to expect bioboxArrival CallWalk-through biobox and answer initial questionsFollow-Up CallEncourage completion, troubleshoot, and confirm return shippingPromptingPrompt on unreturned bioboxes
16. BioBox Lab Pilot and Field PretestsBioBox lab pilot (n=60)Design of the BioBoxBioBooklet instructions Assessed what workedSmall field pretest: phone questionnaire + BioBox (n=48)Integration of questionnaire + BioBoxConsent process and languageMailing and return protocolsInterviewer follow-up call content and processBiobox development
17. BioBox Field Pretests ContinuedLarge field pretest: web/phone/PAPI questionnaire + BioBox (n=415)ScalabilityExperimentImpact of BioBox length: short (1 hr) vs. long (1 ½ hrs)Impact of including biosamples and bloodBiobox development
18. Biobox results from large pretestBlood (n=323)No Blood (n=303)Percent ConsentedPercent ConsentedShortNo Biosample72%71%ShortBiosample66%67%LongBiosample57%70%Pretest Experiment: Consent to Receive BioBox
19. Biobox results from large pretest Blood (n=205)No Blood (n=210)Percent ReturnedPercent ReturnedShortNo Biosample84%89%ShortBiosample79%87%LongBiosample67%75%Pretest Experiment: Return BioBox
20. Round 4 biobox resultsCurrently in Round 4Selected short BioBox (1 hr) with some biosamplesWeb/phone/PAPI questionnaire + BioBox (n=1884)EligiblityBioBoxTasso (blood collection device)
21. Round 4 biobox resultsBioBox %(n=1579)Tasso %(n=305)Consented82%92%Refused18%8%*Round 4 remote data collection is still ongoingBioBox preliminary consent rate from R4*
22. Round 4 biobox resultsBioBox % (n=1300)Tasso %(n=280)Returned84%93%Did not Return16%7%*Round 4 remote data collection is still ongoingBioBox preliminary return rate from R4*
23. FutureNext steps after Round 4 is completeAnalyze who consents and returns the BioBox vs. those that do not consent and/or return the BioBoxCompare biomeasure data collected by interviewer vs. respondent self-collection
24. acknowledgementsThe National Social Life, Health and Aging Project is supported by the National Institute on Aging and the National Institutes of Health (R01AG021487; R37AG030481; R01AG033903; R01AG043538, R01AG048511). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.NSHAP is directed by Linda J. Waite, Principal InvestigatorNSHAP Co-Investigators: Kathleen A. Cagney, Benjamin Cornwell, William Dale, Louise Hawkley, Elbert Huang, Megan Huisingh-Sheetz, Diane Lauderdale, Edward Laumann, Martha McClintock, Colm O'Muircheartaigh, Jayant Pinto, and L. Philip Schumm.McClintock Survey Biomeasure Laboratory (University of Chicago), Sera Burke (SBDWorks Inc.), and Terri Coughlin (Classic Color Inc.) responsible for BioBooklet designNORC is responsible for data collection design, data collection, and delivery
25. Thank you.Katie O’DohertyPrincipal Research DirectorOdoherty-Katie@norc.org