PDF-(DOWNLOAD)-Bottle of Lies: The Inside Story of the Generic Drug Boom

From an awardwinning journalist an explosive narrative investigation of the generic drug boom that reveals fraud and lifethreatening dangers on a global scaleThe Jungle for pharmaceuticalsMany have hailed the widespread use of generic drugs as one of the most important publichealth developments of the twentyfirst century Today almost 90 percent of our pharmaceutical market is comprised of generics the majority of which are manufactured overseas We have been reassured by our doctors our pharmacists and our regulators that generic drugs are identical to their brandname counterparts just less expensive But is this really trueKatherine Ebans Bottle of Lies exposes the deceit behind genericdrug manufacturingand the attendant risks for global health Drawing on exclusive accounts from whistleblowers and regulators as well as thousands of pages of confidential FDA documents Eban reveals an industry where fraud is rampant companies routinely falsify data and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit confident in their ability to fool inspectors Meanwhile patients unwittingly consume medicine with unpredictable and dangerous effectsThe story of generic drugs is truly global It connects middle America to China India subSaharan Africa and Brazil and represents the ultimate litmus test of globalization what are the risks of moving drug manufacturing offshore and are they worth the savings A decadelong investigation with international sweep highstakes brinkmanship and big money at its core Bottle of Lies reveals how the worlds greatest publichealth innovation has become one of its most astonishing swindles A NEW YORK TIMES BESTSELLER New York Times 100 Notable Books of 2019New York Public Library Best Books of 2019 Kirkus Reviews Best Health and Science Books of 2019Science Friday Best Books of 2019 . 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From an award-winning Fortune reporter, an explosive narrative investigation of the generic drug boom that reveals the life-threatening dangers posed by globalization—The Jungle for pharmaceuticalsThe widespread use of generic drugs has been hailed as one of the most important public health developments of the twentieth century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our pharmacists, our doctors, and our regulators that the generic and brand-name drugs are identical, generics just cheaper. But is this really true?Katherine Eban’s Bottle of Lies exposes the widespread deceit behind generic drug manufacturing—creating terrifying risks for global health. Drawing on exclusive accounts from whistleblowers, inspectors, and regulators, as well as thousands of pages of confidential internal FDA documents, Eban reveals an industry where fraud is rampant, companies falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit. Meanwhile, patients unwittingly consume adulterated medicine with unpredictable and even life-threatening effects. The story of generic drugs is truly global: it connects middle America to sub-Saharan Africa, China, India, and Brazil, and encompasses every market banking on the promise of a low-cost cure. Given that tens of millions of patients take drugs of dubious quality approved with fake data, the generics industry is the ultimate litmus test of globalization: what is the risk of moving drug manufacturing offshore, and is it worth the savings?       An investigation with international sweep, exotic settings, molecular mayhem, and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.   1 of 6 This bulletin focuses on the prescribing of branded generic drugs in primary care. It looks at the possible provides some principles to apply if considering branded generics during formulary r patent brand-name medicines. Low-cost generic drugs—Food and Drug Administration (FDA)-approved, interchangeable versions of the same products made by different manufacturers—were considered Oil containment booms are temporary floatation barriers that contain an oil or chemical spill within a water area. 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