reduced CBF under anesthesia CBF matches CMR no CBF CBF ltltlt CMR Thrombus Embolus cerebral hypoperfusion CBF reduced CBF lt CMR no CBF CBF ltltltlt CMR cerebral ID: 1042546
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1. awake CBF(CBF matches CMR) reduced CBF under anesthesia(CBF matches CMR)no CBF(CBF <<< CMR)ThrombusEmboluscerebral hypoperfusion, CBF reduced(CBF < CMR)no CBF(CBF <<<< CMR)cerebralischemiacerebral hypoperfusion, CBF reduced(CBF << CMR)cerebralischemiageneral anesthetic administrationcerebral vasoconstrictionreduced but adequate CBF(neurovascular coupling)brainCMRCBFbrainCMRCBFlargerCMR-CBF discrepancysmallerCMR-CBF discrepancythrombusembolusclampingthrombusembolusclampingCMRnormalCMRreducedSupplementary Figure 1: The discrepancy between cerebral metabolic rate and cerebral blood flow caused by cerebral ischemia in awake and anesthetized subjects.CBF, cerebral blood flow; CMR, cerebral metabolic rate