PDF-TURQUOISE II: Genotype 1a SVR12 Based on Prior Treatment Source: Poord

Author : stefany-barnette | Published Date : 2015-11-21

TURQUOISE II Genotype 1b SVR12 Based on Prior Treatment Source Poordad F et al N Engl J Med 2014370197382 1000 1000 857 1000 1000 1000 1000 1000 0 20 40 60 80 100

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TURQUOISE II: Genotype 1a SVR12 Based on Prior Treatment Source: Poord: Transcript


TURQUOISE II Genotype 1b SVR12 Based on Prior Treatment Source Poordad F et al N Engl J Med 2014370197382 1000 1000 857 1000 1000 1000 1000 1000 0 20 40 60 80 100 No Prior Treatment P. Learning AZ uses objective quantitative and subjective qualitative Leveling Criteria to measure text complexity aa aa TURQUOISE-II. Phase 3. . Treatment. Naïve and Treatment . Experienced. Poordad. F, et al. N . Engl. J Med. 2014;370:1973-82.. Compensated Cirrhosis. Source: . Poordad. F, et al. N . Engl. J Med. 2014;370:1973-82.. Co-formulated . ombitasvir. (OBV)/. paritaprevir. (PTV)/. rironavir. (r) :. 25/150/100 mg QD = 2 tablets. Dasabuvir. (DSV) : 250 mg bid. Objective. SVR. 12. (HCV RNA < 25 IU/ml). TURQUOISE-III . OBV/PTV/r + . DSV . + RBV. OBV/PTV/r + . DSV . + RBV. Randomisation*. 1 : . 1. Open-label. 18-70 years. HCV genotype 1. HCV RNA ≥ 10,000 IU/ml. Naïve or pre-treated with PEG-IFN + RBV. HIV infection, on ATV/. 400/100/100 mg QD. N = 501. N = 440. W8. SOF/VEL 400/100 mg QD. >. 18 years. Chronic HCV infection. Genotype 1, 2, 3, 4, 5 or 6. Treatment-naïve or . IFN-experienced. Compensated cirrhosis **. allowed . Randomisation. Open-label. W8. * Liver biopsy or . Fibroscan. . > 12.5 . kPa. or . Fibrotest. . . >. 0.75 + APRI . > 2. Objective. Primary endpoint: SVR. 12 . (HCV RNA < 15 IU/mL), full analysis set . Open label. ≥ . 18 years. HCV genotype 4, 5 or 6. BMI ≥ 18 kg/m. 2. Treatment-naïve or treatment-experienced with IFN or PEG-IFN . +.  RBV or SOF + RBV . +.  PEG-IFN. No cirrhosis **. Creatinine clearance ≥ 50 mL/min. -. 0938 in GT 1-4. QUANTUM. Phase . 2b. Treatment. . Naïve . Lalezari. JP, et al. EASL. 2013; Abstract 845. . Source: . Lalezari. JP, et al. EASL. 2013; Abstract 845. . Sofosbuvir, Ribavirin, & GS-0938 in . in Genotype 3. ASTRAL-3. Phase 3. . Treatment. . Naïve & Experienced. Foster GR, . et al. . N . Engl. J Med. . 2015. ;373:2608-17.. *Published in tandem with ASTRAL-2 Trial. Source: Foster GR, . Interim Analysis of a French Multicenter Compassionate Use Program. Christophe Hézode,. 1. Victor De Ledinghen,. 2. Helene Fontaine,. 3. Fabien Zoulim,. 4. Pascal Lebray,. 5. Nathalie Boyer,. 6. Markov Models of Haplotype Diversity. Justin Kennedy. Dissertation . Defense for . the Degree of Doctorate in Philosophy. Computer Science & Engineering Department. University of Connecticut. 1. Outline. 20. th. International AIDS Conference. • . Melbourne, Australia . • . 21 July . 2014. Mark S. Sulkowski. , Joseph J. Eron, David Wyles, Roger Trinh, Jay Lalezari, Jihad Slim, Joseph Gathe, Peter J. Ruane, Chia Wang, Richard Elion,. Dr. Sonalika’s Eye Clinic provide the best Eye infection treatment, Conjunctivitis treatment in pune, Hadapsar, Amanora, Magarpatta, Mundhwa, Kharadi Rd, Viman Nagar, Wagholi, and Wadgaon Sheri Dr. Sonalika’s Eye Clinic provide the best Conjunctivitis (Pink Eye) treatment in Pune, Hadapsar, Amanora, Magarpatta, Mundhwa, Kharadi Rd, Viman Nagar, Wagholi, and Wadgaon Sheri

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