JEOPARDY 100 200 300 400 100 200 300 400 400 400 400 300 300 300 200 200 200 100 100 100 Cure Dictionary Gene Therapy Immune based Therapy Kick and Kill ID: 255351
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HIV Cure Research
JEOPARDY!Slide2
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Cure Dictionary
Gene Therapy
Immune based Therapy
Kick and Kill
Stem Cell
R
esearchSlide3
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What receptor does HIV need to bind and enter a cell?Slide4
Very small numbers of HIV infected cells persist below detectable levels while off treatment
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Someone who can keep nearly undetectable levels of virus without antiretroviral therapy for less than 10 years
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This cell type makes up the majority of the HIV reservoir
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Drugs that prompt resting cells to start producing virus are called?
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Researchers pursuing a kick and kill strategy have this aim?
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A cell in the latent state may need _______ rounds of stimulation to start purging virusSlide10
The largest class of latency reversing agents currently being pursued
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Remove the CCR5 receptor from immune cells
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A challenge of gene therapy
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Scientist study THIS group to determine new pathways to achieve viral load control
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Pluripotent stem cells are generated from a biopsy of THIS organ
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A person who has two deleted gene copies of CCR5 is called ____?Slide16
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The process of killing a host or native immune systemSlide17
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A person must have what ancestry in order to be homozygous for CCR5?Slide18
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An extremely rare but potential side effect for stem cell transplantation with a recipient who has cancer and a donor who is CCR5 negative.Slide19
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This strategy can/will be used in combination. Perhaps providing the “kill” in a kick and kill strategySlide20
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This substance binds to a wide variety of HIV strainsSlide21
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hat does the term “
fiebig stage” refer? Slide22
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This immune based strategy turns off the pathway that dampens the immune system. Slide23
The Mississippi child was off treatment for ___ months
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These four topic areas are challenges for finding a cure to HIV.
FINAL JEOPARDY