Dr Karim Berkouk Deputy Head of Unit DG for Research and Innovation Health Directorate European Commission Ageing population Increased disease burden chronic diseases Health amp care sector unsustainable ID: 734609
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Slide1
An overview of the EC’s research initiatives for healthcare
Dr Karim Berkouk,Deputy Head of UnitDG for Research and InnovationHealth DirectorateEuropean Commission Slide2
Ageing population
Increased disease burden: chronic diseasesHealth & care sector unsustainable: under pressure to reformHealth industry under pressure for innovative solution
Health main challengesSlide3
Early
origins of lung diseases: prenatal nutritional deficiencies or maternal smoking; severe early infections; genetic and epigenetic factors related to the natural and anthropogenic environmentLifestyle and lung health: nutrition, active and passive smoking, physical inactivity, social inequitiesEnvironment: ozone and particulate matters , occupational exposure, indoor air quality and nanomaterials Early diagnosis, vaccines and treatments (especially for resistant pathogens) lung infectionsAgeing population: comorbidities, increased disease and economic burden
Respiratory Diseases (RD) main
challenges
From the European
Respiratory
roadmap
. Recommendations for the future of respiratory medicine. European Respiratory Society. 2011. Slide4
The EU meansSlide5
FP 7 - State of Play
Health researchKey figures5,5 b€ invested to date1053 projects12 520 participations3 615 organisations 123 countries
First outcomes
(on
363
closed projects)
12 269
publications
3,1
average
SJR* publication
228 patent applications 31 spin-offs created
* SCImago Journal RankingSlide6
basic research
translational research COPD Pneumonia Asthma TuberculosisCollaborative research: 236
Frontier Research: 32
SME: 9
Training & Mobility: 14
€
290
Million on
Respiratory Diseases
(in million Euro)Slide7
Large
cohort studies in asthma and COPD by studying specific genetic markers and related phenotypes e.g.:longitudinal, population based studies: MeDALL, COPACETIC, EVA, ESCAPE birth cohort studies: CHICOS Drug development, personalised medicine & TechnologyPrognostic & PM: AirPROM, U-BIOPREDTechnology for home care (HOMECARE) and bio-artificial lung (Ambulung )
Respiratory infections
(e.g
.
TB ;
antimicrobial
resistance)Coordinating research in RD in Europe (EARIP)
FP7 Overview 2007-2013 Slide8
€ 16.8 million
http://www.proactivecopd.com
Aim: to
develop new tools that will enable patients, their doctors and clinical researchers
to accurately assess the improvement or deterioration
of
COPD.
Tools tested on more
than 600 COPD
patients:
A
user friendly electronic tool will help patients to assess on a day-to-day basis the activities in which they engage and the symptoms associated to these activities.
Another
tool
will be used during hospital visits to assess the patients' physical activity and experience of the disease.
Physical
Activity as a Crucial Patient Reported Outcome in
COPD (
PROactive
)Slide9
Horizon 2020
PerspectivesSlide10
Three
prioritiesExcellent scienceIndustrial leadershipSocietal challenges
European Research Council
Future and Emerging Technologies
Marie
Skłodowska
-Curie actions
Research infrastructures
Leadership in enabling and industrial technologies
Access to risk finance
Innovation in SMEs
Health, demographic change and wellbeing
Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the
Bioeconomy
Secure, clean and efficient energy
Smart, green and integrated transport
Climate action, environment, resource efficiency and raw materials
Inclusive, innovative and reflective societies
Secure societies
Science with and for society
Spreading excellence and widening participation
Budget:
about €79 BillionSlide11
Advancing active and healthy ageing
Integrated, sustainable, citizen-centred care
Improving health information, data exploitation and providing an evidence base for health policies and regulation
Innovative treatments and technologies
Improving diagnosis
Effective health promotion, disease prevention,
preparedness and screening
Understanding health, ageing & disease
WP 2014/2015: €
1,2
billion
Funding: € 7.5 Billion
Health, Demographic change and
wellbeingSlide12
Understanding health, ageing and disease: determinants, risk factors and pathways
Comparing the effectiveness of existing healthcare interventions in the elderlyNew therapies for chronic non-communicable diseases Health promotion and disease prevention: translating ‘omics’ into stratified approaches Evaluating existing screening and prevention programmesAdvancing bioinformatics to meet biomedical and clinical needs Topics 2014 relevant for RDSlide13
Understanding common mechanisms of diseases and their relevance in
co-morbiditiesHealth promotion and disease prevention (environment and health based interventions)Development of new diagnostic tools and technologies: in vivo medical imaging technologiesTools and technologies for advanced therapies Establishing effectiveness of health care interventions in the paediatric populationPiloting personalised medicine in health and care systemsTopics 2015 relevant for RDSlide14
Strategic Initiatives
Innovative Medicines Initiative 2 www.imi.europa.eu
European & Developing Countries Clinical Trials Partnership (EDCTP2)
www.edctp.org
Active and Assisted Living 2
www.aal-europe.eu
European Innovation Partnership on Active and Healthy Ageing
https://webgate.ec.europa.eu/eipahaSlide15
International
cooperation: how?Identify and define sharedstrategic goalsAgree to approach jointly andshare tasks (and costs)Let each agency use its own funding mechanisms/timingAgree to share data / standards
Alignment – Flexibility
– Commitment
Example: Global Alliance for Chronic Diseases (GACD)