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First Annual How to Make it Workshop (July 2016) First Annual How to Make it Workshop (July 2016)

First Annual How to Make it Workshop (July 2016) - PowerPoint Presentation

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First Annual How to Make it Workshop (July 2016) - PPT Presentation

Sponsored by CBM 2 and CHANL Agenda DAY 1 Chapman 125 UNC Campus 730 am 800 am Registration 800 am 1200 pm Patterning structures across different length scales General Overview and Introduction ID: 548645

device participants day microfluidic participants device microfluidic day pdms mixing devices lectures information geil casting workshop lithography techniques bob

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Slide1

First Annual How to Make it Workshop (July 2016)

Sponsored byCBM2 and CHANLSlide2

Agenda

DAY 1 (Chapman 125 – UNC Campus)7:30 am – 8:00 am Registration8:00 am – 12:00 pm Patterning structures across different length scales

General Overview and Introduction (

Donley/Soper)

Patterning Microstructures

Non-optical based patterning of structures

Micromilling – Hupert

Laser Ablation – Hupert

Optical Lithography and Etching

Geil Wet etchingDry etching10:00 am -10:15 am BreakPatterning nanostructures – Donley Ion beam millingElectron beam lithographyThin film deposition and Liftoff – Geil E-beam and atomic layer depositionLift-off for patterning thin filmsNoon – 1:30 pm LUNCH1:30 pm – 3:15 pm Replication Techniques – ParkHot EmbossingInjection MoldingNanoimprint Lithography (NIL)PDMS Casting

DAY 2 (Chapman 125 – UNC Campus)

8:00 am – 8:30 am

What is Microfluidics and

Nanofluidics

?

- Soper

Advantages of these platforms

Various substrate materials for micro-/

nanofluidics

8:30 am – 12:00 pm

Device Applications

Witek

Solid-phase extraction

PCR

DNA microarrays

10:00 am – 10:15 am Break

Capillary electrophoresis

- Soper

DNA stretching

- Soper

DNA sequencing

- Soper

12:00 pm – 1:15 pm LUNCH

1:15 pm – 2:15 pm

Metrology

Donley

Profilometry

, SEM, AFM, Contact angle, XPS

2:15 pm – 3:30 pm

Microfluidic Systems for Molecular Analyses

– Murphy

1. Monolithic integration, Modular integration

2. Interconnects, Alignment

for

assembly, Material

3. Examples

– PCR/LDR

assays

for mutation detectionSlide3

First Day Lectures on Prototyping, Lithography and Embossing/Imprinting

Dr. Matt Hupert discusses with the participants information on micromilling and laser ablation as tools for rapidly prototyping microfluidic devices.

Dr. Bob Geil lectures on a variety of techniques, such as photolithography, wet/dry etching and PDMS casting.

Prof. Sunggook Park provides information on replication based techniques for building microfluidic and nanofluidic devices.Slide4

Process Demonstrations: Lithography, FIB, Laser Ablation and Hot Embossing

Dr. Matt Hupert discusses with the participants information on micromilling and laser ablation as tools for rapidly prototyping microfluidic devices.Dr. Bob Geil lectures on a variety of techniques, such as photolithography, wet/dry etching and PDMS casting.Prof. Sunggook Park provides information on replication based techniques for building microfluidic and nanofluidic devices.Slide5

Second Day Lectures on Metrology and the Potential Uses of Microfluidics

Dr. Maggie Witek discusses the various uses of microfluidic devices for bioanalytical applications, such as PCR, and mutation detection.Prof. Michael Murphy shares with the participants information related to integrating devices together to build functional systems.Workshop participants enjoying the hearty lectures on Days 1 and 2 of the Workshop.Slide6

Agenda

DAY 1 and DAY 2Process Demonstrations (3:45 pm – 5:30 pm)Photolithography (Bob)

Rapid Prototyping (Varshni)

FIB milling (Amar)

Hot Embossing (Swathi)

 DAY 3 (235 Chapman Hall – UNC Campus)

8:30 am Work in teams of 2 and carry out the following steps (Team):

1. Build a microfluidic deviceUsing molding tool and PDMS casting to build a device with/without a herringbone mixer to mix water with a dye solution

 

2. Perform metrology on device

Optical Microscopy of structures 3. Device assemblyPlasma treatment of PDMS deviceAssemble to glass microscope slide Fluidic mixing of a dye solution and waterOptical microscopy12:00 pm – 1:00 pm LUNCHPresentations – Each team will present slides addressing these pointsWhat are the advantages and disadvantages of using PDMS for microfluidics?Metrology of device. Why was the PDMS treated with O2 plasma prior to assembly?Effects of herringbone mixer on mixing time.Without the herringbone, what induces the mixing?Slide7

Day 3: Hands on – Making a Microfluidic Device for Mixing

Dr. Witek (right) discussing concept of mixing fluidic device with workshop participants.

Drs. Donley and Witek (right) talking to participants on how to use the device that was just made.

Participants using their microfluidic device for the mixing of two reagents and watching the evolution of the mixing with a microscope.

Participants are working on casting PDMS against an SU8 relief that was made the previous day in the lithography process demonstration.Slide8

Day 3: Hands on – Making a Microfluidic Device for Mixing

Participants engaged in deep discussion about microfluidics.

Dr. Bob Geil discusses the process of casting PDMS against SU-8 reliefs and then assembling the device by plasma treating the PDMS and

conformally sealing to a glass slide.Dr. Bob Geil talking to Prof. David Kaufman about building microfluidic devices.

Workshop participants carefully going over their data on the performance of their microfluidic device.Slide9

TOTAL NUMBER OF PARTICIPANTS - 15Slide10

Workshop Feedback

Summary of participant comments:Participants wanted more information in advance.Schedule should be posted and advertised when people register.Schedule should be e-mailed to participants before they arrive.Information on food to be served should be e-mailed.2. Lectures need to be broken into smaller chunks.3. Some lectures were too long (Park and Murphy), others too detailed.4. Participants were looking for more variety in the types of applications presented on day 2.5. Breaks were too long. Shorter breaks could lead to getting out earlier.6. Some speakers were too quiet (audience members were likely sitting in back where some ventilation makes it hard to hear).

7. A smaller classroom might have been a better venue for such a small audience.8. Flash drive with content was a good idea.9. Guests would appreciate wi-fi access.

10. Parking situation was a bit unclear.11. Fewer people should be allowed in the cleanroom at once to reduce wait times.Some attendees struggled with the 8:00am start time, and didn’t make it until later. A start time of 8:30 or 9:00am might mean that more attendees get to see everything. A later starting time would also make things easier on the organizers.