PPT-Graph clustering to detect network modules

Sushmita Roy sroybiostatwiscedu Computational Network Biology Biostatistics amp Medical Informatics 826 Computer Sciences 838 httpscompnetbiocoursediscoverywiscedu Nov 1 st 2016 Some material is adapted from lectures from Introduction to Bioinformatics. Adapted from Chapter 3. Of. Lei Tang and . Huan. Liu’s . Book. Slides prepared by . Qiang. Yang, . UST, . HongKong. 1. Chapter 3, Community Detection and Mining in Social Media.  Lei Tang and Huan Liu, Morgan & Claypool, September, 2010. . and Physical Interaction . Datasets. Manikandan Narayanan, Adrian Vetta, Eric E. Schadt, Jun Zhu. PLoS Computational Biology 2010. Presented by: Tal Saiag. Seminar in Algorithmic Challenges in Analyzing Big Data* in Biology and . April 22, 2010. Last Time. GMM Model Adaptation. MAP (Maximum A Posteriori). MLLR (Maximum Likelihood Linear Regression). UMB-. MAP. for speaker recognition. Today. Graph Based Clustering. Minimum Cut. Sparsification for Graph Clustering. Peixiang Zhao. Department of Computer Science. Florida State University. zhao@cs.fsu.edu. Synopsis. Introduction. gSparsify. : Graph motif based sparsification. Cluster significance. Lecture outline. Distance/Similarity between data objects. Data objects as geometric data points. Clustering problems and algorithms . K-means. K-median. K-center. What is clustering?. A . grouping. of data objects such that the objects . Sushmita Roy. sroy@biostat.wisc.edu. Computational Network Biology. Biostatistics & Medical Informatics 826. Computer Sciences 838. https://compnetbiocourse.discovery.wisc.edu. Nov 3. rd. , Nov 10. One of these things is not like the other…. spectral clustering (a la Ng-Jordan-Weiss). data. similarity graph. edges have weights . w. (. i. ,. j. ). e.g.. the . Laplacian. diagonal matrix . D. Normalized . Cluster Analysis. Outline. Introduction to Cluster Analysis. Types of Graph Cluster Analysis. Algorithms for Graph Clustering. k-Spanning Tree. Shared Nearest Neighbor. Betweenness Centrality Based. Highly Connected Components. Unsupervised . learning. Seeks to organize data . into . “reasonable” . groups. Often based . on some similarity (or distance) measure defined over data . elements. Quantitative characterization may include. Lecture outline. Distance/Similarity between data objects. Data objects as geometric data points. Clustering problems and algorithms . K-means. K-median. K-center. What is clustering?. A . grouping. of data objects such that the objects . Distance matrices are graphs .  as useful as any other clustering. Identification of communities in social networks. Webpage clustering for better data management of web data. Outline. Min s-t cut problem. Produces a set of . nested clusters . organized as a hierarchical tree. Can be visualized as a . dendrogram. A tree-like diagram that records the sequences of merges or splits. Strengths of Hierarchical Clustering. What is clustering?. Grouping set of documents into subsets or clusters.. The Goal of clustering algorithm is:. To create clusters that are coherent internally, but clearly different from each other. Sushmita Roy. sroy@biostat.wisc.edu. Computational Network Biology. Biostatistics & Medical Informatics 826. https://compnetbiocourse.discovery.wisc.edu. Nov 1. st. 2018. Goals for today. Finding modules on graphs/Community structure on graphs/Graph clustering.