Program Goals The Incretin System Response to Oral Glucose Injected Incretinbased Agents GLP1 Receptor Agonists Oral Incretinbased Agents DPP4 Inhibitors Main Pathophysiological Defects in T2D ID: 742158
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Injectable Options as Add-Ons to Basal Insulin: Targeting PPG in Type 2 Diabetes PatientsSlide2Slide3
Program GoalsSlide4
The Incretin System: Response to Oral GlucoseSlide5
Injected Incretin-based Agents: GLP-1 Receptor AgonistsSlide6
Oral Incretin-based Agents: DPP-4 Inhibitors Slide7
Main Pathophysiological Defects in T2DSlide8
T2D Anti-Hyperglycemic Therapy: General RecommendationsSlide9Slide10
Approaches to Intensifying Therapy in Patients Not At Goal on Basal InsulinSlide11
Adding Prandial Insulin to Basal Insulin: Key Challenges Slide12
Scientific Rationale for Combining Basal Insulin with a GLP-1 agonistSlide13
DPP- 4 Inhibitors as Add-ons to Basal InsulinSlide14
Pramlintide as Add-on to Basal InsulinSlide15
Twice-daily Exenatide as Add-on to Basal Insulin (Glargine)Slide16
Twice-daily Exenatide as Add-on to Basal Insulin (Glargine): ResultsSlide17
Metformin plus Liraglutide Followed by Add-on of Basal Insulin (Detemir)Slide18
Metformin plus Liraglutide Followed by Add-on of Basal Insulin (Detemir)Slide19
Oral Agents Plus Basal Insulin (Glargine) Followed by Add-on Lixisenatide*Slide20
Oral Agents Plus Basal Insulin (Glargine) Followed by Add-on Lixisenatide* (cont)Slide21Slide22
Other Safety Concerns With GLP-1 Receptor AgonistsSlide23
Lixisenatide* vs Liraglutide: Effect on Postprandial Glucose Levels†Slide24
Comparison of Basal Insulin + Lixisenatide* and Basal-Plus RegimensaSlide25
IDegLira* vs Degludec* or Liraglutide Alone: Effect on HbA1cSlide26
IDegLira* vs Degludec* or Liraglutide Alone: ResultsSlide27Slide28
AbbreviationsSlide29
Abbreviations (cont)Slide30
ReferencesSlide31
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