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Out With the Old and In With the New, Again? Out With the Old and In With the New, Again?

Out With the Old and In With the New, Again? - PowerPoint Presentation

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Out With the Old and In With the New, Again? - PPT Presentation

Out With the Old In With the New Current Standard of Care NEUTRINO and FISSION SOF RBV pegIFN for Treatmentnaive Patients NEUTRINO and FISSION SOF RBV pegIFN for Treatmentnaive Patients ID: 357018

rbv hcv patients treatment hcv rbv treatment patients infection cont weeks references sof pegifn ion 450 ombitasvir naive dasabuvir

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Presentation Transcript

Slide1

Out With the Old and In With the New, Again?Slide2

Out With the Old, In With the NewSlide3

Current Standard of CareSlide4

NEUTRINO and FISSION

SOF + RBV ± pegIFN for Treatment-naive PatientsSlide5

NEUTRINO and FISSION

SOF + RBV ± pegIFN for Treatment-naive PatientsSlide6

FUSION

SOF + RBV ± pegIFN in Treatment-experienced Patients With G2,3 HCVSlide7

VALENCESOF + RBV for 12 Weeks or 24 Weeks in G2 or G3 HCV Infection Slide8

QUEST 1 and 2Q80K Variant Adversely Affects SVR12 of SMV-based TherapySlide9

COSMOS

SOF + SIM ± RBV for G1 HCV-infected Patients by Fibrosis StageSlide10

2014

AASLD HCV Treatment GuidelinesSlide11

ION-1On the Road to IFN-free Therapy for G1 HCV InfectionSlide12

ION-3

8 Weeks or 12 Weeks of SOF/LDV for Treatment-naive G1 HCV InfectionSlide13

ION-2SOF/LDV in G1 HCV-infected Patients Failing PegIFN/RBV ± DAASlide14

HALLMARK-DUALPhase 3 Trial of the All-oral Regimen DCV + ASV for G1b HCV InfectionSlide15

SAPPHIRE IABT-450/r/Ombitasvir + Dasabuvir (3D) + RBV for G1 HCV InfectionSlide16

SAPPHIRE IIABT-450/r/Ombitasvir + Dasabuvir + RBV (3D) G1 HCVSlide17

TURQUOISE IIABT-450/r/Ombitasvir + Dasabuvir (3D) + RBV in CirrhosisSlide18

The Past And Future of HCV TherapySlide19

AbbreviationsSlide20

Abbreviations (cont)Slide21

Abbreviations (cont)Slide22

ReferencesSlide23

References (cont)Slide24

References (cont)Slide25

References (cont)

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