PPT-1 Syphilis Treponema pallidum

2 Learning Objectives Upon completion of this content the learner will be able to Describe the epidemiology of syphilis in the US Describe the pathogenesis of T pallidum Discuss the clinical manifestations of syphilis. Treponema pallidum. . 2. Learning Objectives. Upon completion of this content, the learner will be able to. Describe the epidemiology of syphilis in the U.S.. Describe the pathogenesis of . T. . pallidum. . 2. Learning Objectives. Upon completion of this content, the learner will be able to. Describe the epidemiology of syphilis in the U.S.. Describe the pathogenesis of . T. . pallidum. .. Discuss the clinical manifestations of syphilis.. Origins of Syphilis. First . unambiguous case of syphilis recorded in 1495. From New World. The Faster Times. “Travel’s With “. Lapham’s. Quarterly”: Christopher Columbus Will Trade Cotton For Gold, 1493” (http://thefastertimes.com/slowtravel/2009/11/05/travels-with-laphams-quarterly-christopher-columbus-will-trade-cotton-for-gold-1493/). Existen por lo menos tres subespecies conocidas: . T. pallidum . pallidum. , causante de la sífilis; . T. pallidum pertenue. , causante de la frambesia (también llamada buba o pián); y . T. pallidum endemicum. National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention Division of STD Prevention CS246943APage 2 of 2 Using latex condoms the right way https//wwwcdcgovcondomeffectiveness/male-condom-use syphilisTHE FACTS149disease STD149Anyone can get syphilis149Many people who have syphilis don146t know it You can have syphilis even if you don146t notice any symptoms149The 31rst symptom is a painles Gram- negative, spirochete with fine spirals and pointed or round ends.. ~ 10 micrometers long and0.1-0.2 micrometers wide.. Not been successfully cultivated in artificial media.. T.pallidum. - endemic syphilis. “The Great Imitator”. 20. affects approximately . 32,000. people each year in the U.S.. 14. How is Syphilis Spread?. Direct contact with a syphilis sore (chancre) during vaginal, anal, or oral sex.. What is Syphilis?. Caused by the bacterium . Treponema. pallidum. Time between infection and start of first symptom is 10-90 days . Diagnosed by . Dark field microscopy of material taken from a lesion or lymph node . Workshop for the Training of HCW. [Enter date, location of workshop]. Learning Objectives. By the end of . this module, . participants should:. Understand of the global epidemiology of syphilis and congenital syphilis. Ulrich von Hutten, 1488-1523. The French Pox or Gallus . Morbicus. = venereal Syphilis? . Syphilis. is a sexually transmitted infection caused by the spirochete bacterium . Treponema. . pallidum. , Associate professor. DEPT OF PATHOLOGY, SKHMC, Kulasekharam. TREPONEMA. Spirochetes . The spirochetes (from . Speira. , meaning coil and . chaite. , meaning hair) are elongated, motile, slender, . helically coiled, flexible organisms with one or more . Immunityinsyphilis301TABLEIHumantreponemesTreponemalstrainsT.pallidum(Nicholspathogenic)Nichols(non-pathogenic)Kazan2Kazan4Kazan5Kazan8TrefringensT.minutumT.ambiguaT.microdentiumBiologicaloriginsC.S.F Gonorrhoea. .. Prokofyeva. Nina, MD. PhD. Department of Dermatology and Venereology of Odessa National Medical University. More than 1 million sexually transmitted infections (STIs) are acquired every day .