Dimension Reduction PCA, tSNE, UMAP, Integration

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Dimension Reduction PCA, tSNE, UMAP, Integration v2024-02 Simon Andrews simon.andrewsbabraham.ac.uk Where are we heading? Each dot is a cell Groups of dots are similar cells Separation of groups could be interesting biology Too much data!

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01
Dimension Reduction PCA, tSNE, UMAP, Integration v2024-02

Simon Andrews
simon.andrews@babraham.ac.uk<br>
02
Where are we heading? Each dot is a cell

Groups of dots are similar cells

Separation of groups could be interesting biology<br>
03
Too much data! 5000 cells and 2500 measured genes
Realistically only 2 dimensions we can plot (x,y)<br>